SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4r0b GLYCODELIN
(Homo
sapiens) 		4 / 5 THR A 112
THR A 111
GLU A  91
THR A  93
 None
 1.41A 1d4fB-4r0bA:
undetectable		 1d4fB-4r0bA:
16.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		5 / 9 LEU A  39
LEU A  58
GLU A  62
LYS A  69
GLN A 120
 None
 1.10A 1gx8A-4r0bA:
21.5		 1gx8A-4r0bA:
41.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		6 / 11 LEU A  39
VAL A  41
ILE A  56
GLU A  62
LYS A  69
GLN A 120
 None
 0.86A 1gx9A-4r0bA:
21.6		 1gx9A-4r0bA:
41.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 4r0b GLYCODELIN
(Homo
sapiens) 		4 / 5 ILE A 137
ALA A  25
MET A 133
PHE A 140
 None
 0.99A 4dc3B-4r0bA:
undetectable		 4dc3B-4r0bA:
18.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		6 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
ILE A  84
LEU A 103
 None
 0.62A 4y0pA-4r0bA:
21.4		 4y0pA-4r0bA:
41.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		7 / 12 VAL A  41
LEU A  46
LEU A  54
ILE A  56
LEU A  58
GLU A  62
ILE A  84
 None
 0.71A 4y0rA-4r0bA:
21.5		 4y0rA-4r0bA:
41.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		5 / 12 VAL A  41
LEU A  54
LEU A  58
GLU A  62
LYS A  69
 None
 0.78A 4y0rA-4r0bA:
21.5		 4y0rA-4r0bA:
41.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4r0b GLYCODELIN
(Homo
sapiens) 		5 / 12 ASP A 109
ALA A  89
PRO A  38
THR A  34
GLU A  28
 None
 1.33A 5hfjC-4r0bA:
undetectable		 5hfjC-4r0bA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4r0b GLYCODELIN
(Homo
sapiens) 		5 / 12 ASP A 109
ALA A  89
PRO A  38
SER A 116
GLU A  28
 None
 1.23A 5hfjD-4r0bA:
undetectable		 5hfjD-4r0bA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		4 / 5 LEU A  15
LEU A 122
THR A  93
ARG A 138
 None
 1.03A 6ew0F-4r0bA:
undetectable		 6ew0F-4r0bA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 4r0b GLYCODELIN
(Homo
sapiens) 		4 / 6 LEU A  15
LEU A 122
THR A  93
ARG A 138
 None
 1.03A 6ew0G-4r0bA:
undetectable		 6ew0G-4r0bA:
21.09