SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 146
TYR A 122
VAL A  13
ASN A 149
VAL A 148
 None
 1.28A 3g0bA-4r0nA:
undetectable		 3g0bA-4r0nA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 146
TYR A 122
VAL A  13
ASN A 149
VAL A 148
 None
 1.28A 3g0bB-4r0nA:
undetectable		 3g0bB-4r0nA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 146
TYR A 122
VAL A  13
ASN A 149
VAL A 148
 None
 1.29A 3g0bC-4r0nA:
undetectable		 3g0bC-4r0nA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 146
TYR A 122
VAL A  13
ASN A 149
VAL A 148
 None
 1.31A 3g0bD-4r0nA:
undetectable		 3g0bD-4r0nA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A  99
VAL A  33
ILE A  85
ARG A  50
LEU A  89
 None
 1.39A 3oxzA-4r0nA:
undetectable		 3oxzA-4r0nA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		3 / 3 SER A 123
ALA A 117
VAL A 116
 None
 0.43A 5xiwC-4r0nA:
undetectable		 5xiwC-4r0nA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 GLY A   8
HIS A  17
SER A 126
SER A 127
 None
SO4  A 201 (-4.1A)
SO4  A 201 (-4.7A)
SO4  A 201 (-2.9A)
 0.26A 6jmjA-4r0nA:
24.4		 6jmjA-4r0nA:
41.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 7 GLY A   8
PHE A  10
HIS A  17
SER A 126
SER A 127
 None
None
SO4  A 201 (-4.1A)
SO4  A 201 (-4.7A)
SO4  A 201 (-2.9A)
 0.27A 6jnhA-4r0nA:
24.5		 6jnhA-4r0nA:
41.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 7 PHE A  10
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
SO4  A 201 (-4.1A)
SO4  A 201 (-3.8A)
SO4  A 201 (-4.7A)
SO4  A 201 (-2.9A)
 0.67A 6jnhA-4r0nA:
24.5		 6jnhA-4r0nA:
41.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 6 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
SO4  A 201 (-4.1A)
SO4  A 201 (-3.8A)
SO4  A 201 (-4.7A)
SO4  A 201 (-2.9A)
 0.65A 6jogA-4r0nA:
24.4		 6jogA-4r0nA:
41.72