SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 9 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.83A 1bkfA-4r0xA:
18.9		 1bkfA-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.76A 1c9hA-4r0xA:
18.7		 1c9hA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 1c9hA-4r0xA:
18.7		 1c9hA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.82A 1fapA-4r0xA:
19.3		 1fapA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A 122
 None
 0.94A 1fkbA-4r0xA:
19.3		 1fkbA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
TRP A  90
PHE A 130
 None
 0.68A 1fkbA-4r0xA:
19.3		 1fkbA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.68A 1fkbA-4r0xA:
19.3		 1fkbA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
PHE A 130
 None
 0.67A 1fkfA-4r0xA:
18.9		 1fkfA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
PHE A 130
 None
 0.77A 1fkfA-4r0xA:
18.9		 1fkfA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.84A 1fkfA-4r0xA:
18.9		 1fkfA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.81A 1fkfA-4r0xA:
18.9		 1fkfA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
PHE A 130
 None
 0.66A 1fkjA-4r0xA:
18.9		 1fkjA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
PHE A 130
 None
 0.76A 1fkjA-4r0xA:
18.9		 1fkjA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.85A 1fkjA-4r0xA:
18.9		 1fkjA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.82A 1fkjA-4r0xA:
18.9		 1fkjA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
PHE A 130
 None
 0.69A 1fklA-4r0xA:
19.1		 1fklA-4r0xA:
45.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.75A 1fklA-4r0xA:
19.1		 1fklA-4r0xA:
45.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
ASP A  68
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 1pbkA-4r0xA:
18.6		 1pbkA-4r0xA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
GLY A  84
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.66A 1pbkA-4r0xA:
18.6		 1pbkA-4r0xA:
37.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 9 TYR A  57
ASP A  68
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.85A 1q6iA-4r0xA:
17.0		 1q6iA-4r0xA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 10 TYR A  57
ASP A  68
ARG A  73
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.83A 1q6iB-4r0xA:
16.9		 1q6iB-4r0xA:
27.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.73A 1tcoC-4r0xA:
19.2		 1tcoC-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
TYR A 113
PHE A 130
 None
 0.89A 1tcoC-4r0xA:
19.2		 1tcoC-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
ASP A  68
PHE A  77
TYR A 113
ILE A 122
PHE A 130
 None
 0.92A 1tcoC-4r0xA:
19.2		 1tcoC-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.75A 1tcoC-4r0xA:
19.2		 1tcoC-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.76A 1yatA-4r0xA:
20.9		 1yatA-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.83A 1yatA-4r0xA:
20.9		 1yatA-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.82A 1yatA-4r0xA:
20.9		 1yatA-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 1yatA-4r0xA:
20.9		 1yatA-4r0xA:
44.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		3 / 3 ASP A 136
ASP A  51
ASN A  42
 None
 0.73A 2bm9D-4r0xA:
undetectable		 2bm9D-4r0xA:
18.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.76A 2dg3A-4r0xA:
19.1		 2dg3A-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
PHE A 130
 None
 0.66A 2dg4A-4r0xA:
18.6		 2dg4A-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.65A 2dg4A-4r0xA:
18.6		 2dg4A-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
PHE A 130
 None
 0.62A 2dg9A-4r0xA:
18.9		 2dg9A-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.58A 2dg9A-4r0xA:
18.9		 2dg9A-4r0xA:
44.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
PHE A 130
 None
 0.65A 2fkeA-4r0xA:
19.1		 2fkeA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
PHE A 130
 None
 0.75A 2fkeA-4r0xA:
19.1		 2fkeA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.82A 2fkeA-4r0xA:
19.1		 2fkeA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.79A 2fkeA-4r0xA:
19.1		 2fkeA-4r0xA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
GLN A  85
VAL A  86
ILE A  87
TYR A 113
 None
 1.30A 2vcdA-4r0xA:
14.8		 2vcdA-4r0xA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
PHE A  67
VAL A  86
ILE A  87
TRP A  90
 None
 0.83A 2vcdA-4r0xA:
14.8		 2vcdA-4r0xA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
VAL A  86
ILE A  87
TRP A  90
TYR A 113
 None
 0.85A 2vcdA-4r0xA:
14.8		 2vcdA-4r0xA:
30.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  67
ARG A  73
PHE A  77
VAL A  86
TRP A  90
TYR A 113
PHE A 130
 None
 0.79A 2vn1A-4r0xA:
22.2		 2vn1A-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
PHE A  67
ASP A  68
ARG A  73
PHE A  77
TYR A 113
PHE A 130
 None
 0.86A 2vn1A-4r0xA:
22.2		 2vn1A-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
PHE A  67
ASP A  68
PHE A  77
TYR A 113
ILE A 122
PHE A 130
 None
 0.88A 2vn1A-4r0xA:
22.2		 2vn1A-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  67
PHE A  77
VAL A  86
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.76A 2vn1A-4r0xA:
22.2		 2vn1A-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 10 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
PHE A 130
 None
 0.65A 2vn1B-4r0xA:
22.1		 2vn1B-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
ILE A  87
PHE A 130
 None
 0.83A 2vn1B-4r0xA:
22.1		 2vn1B-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.61A 2vn1B-4r0xA:
22.1		 2vn1B-4r0xA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 PHE A  79
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 1.48A 3ihzA-4r0xA:
21.9		 3ihzA-4r0xA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.83A 3ihzA-4r0xA:
21.9		 3ihzA-4r0xA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 10 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.86A 3ihzA-4r0xA:
21.9		 3ihzA-4r0xA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 8 TYR A  57
ASP A  68
PHE A  77
TRP A  90
TYR A 113
ILE A 122
 None
 0.58A 3ihzB-4r0xA:
22.5		 3ihzB-4r0xA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 10 TYR A  57
ASP A  68
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 3kz7A-4r0xA:
19.0		 3kz7A-4r0xA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 10 TYR A  57
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.60A 3kz7A-4r0xA:
19.0		 3kz7A-4r0xA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		10 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.78A 3o5rA-4r0xA:
23.8		 3o5rA-4r0xA:
93.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.72A 3uf8A-4r0xA:
20.1		 3uf8A-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.81A 3uf8A-4r0xA:
20.1		 3uf8A-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.84A 3uf8A-4r0xA:
20.1		 3uf8A-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 3uf8A-4r0xA:
20.1		 3uf8A-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 10 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.78A 3uqaA-4r0xA:
20.0		 3uqaA-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.92A 3uqaA-4r0xA:
20.0		 3uqaA-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 8 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.61A 3uqbA-4r0xA:
19.7		 3uqbA-4r0xA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 8 TYR A  57
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.58A 3uqbA-4r0xA:
19.7		 3uqbA-4r0xA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.78A 3vawA-4r0xA:
19.7		 3vawA-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.88A 3vawA-4r0xA:
19.7		 3vawA-4r0xA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 12 TYR A  57
ASP A  68
PHE A  77
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.67A 4drhA-4r0xA:
21.5		 4drhA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 12 TYR A  57
PHE A  77
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.63A 4drhA-4r0xA:
21.5		 4drhA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		10 / 12 TYR A  57
ASP A  68
PHE A  77
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 4drhD-4r0xA:
21.6		 4drhD-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ARG A  73
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.81A 4driA-4r0xA:
23.9		 4driA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
ARG A  73
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.86A 4driA-4r0xA:
23.9		 4driA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
PHE A  77
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.69A 4driA-4r0xA:
23.9		 4driA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
PHE A  77
GLN A  85
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.59A 4driA-4r0xA:
23.9		 4driA-4r0xA:
85.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.75A 4drjA-4r0xA:
23.2		 4drjA-4r0xA:
68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.66A 4drjA-4r0xA:
23.2		 4drjA-4r0xA:
68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 PHE A  79
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 1.47A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.87A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 PHE A  79
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 1.45A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.86A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 4dz2A-4r0xA:
19.8
4dz2B-4r0xA:
19.8		 4dz2A-4r0xA:
45.83
4dz2B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 PHE A  79
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 1.43A 4dz3A-4r0xA:
19.9		 4dz3A-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.73A 4dz3A-4r0xA:
19.9		 4dz3A-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.84A 4dz3A-4r0xA:
19.9		 4dz3A-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 4dz3A-4r0xA:
19.9		 4dz3A-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 PHE A  79
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 1.41A 4dz3B-4r0xA:
14.7		 4dz3B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ARG A  73
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 4dz3B-4r0xA:
14.7		 4dz3B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
ARG A  73
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.76A 4dz3B-4r0xA:
14.7		 4dz3B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 4dz3B-4r0xA:
14.7		 4dz3B-4r0xA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 TYR A  57
ASP A  68
PHE A  77
ILE A  87
TYR A 113
PHE A 130
 None
 0.82A 4laxA-4r0xA:
23.1		 4laxA-4r0xA:
57.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.66A 4laxA-4r0xA:
23.1		 4laxA-4r0xA:
57.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.84A 4nnrA-4r0xA:
15.8
4nnrB-4r0xA:
15.9		 4nnrA-4r0xA:
40.85
4nnrB-4r0xA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.68A 4nnrA-4r0xA:
15.8
4nnrB-4r0xA:
15.9		 4nnrA-4r0xA:
40.85
4nnrB-4r0xA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 TYR A  57
ASP A  68
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 4nnrB-4r0xA:
15.9		 4nnrB-4r0xA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.70A 4nnrB-4r0xA:
15.9		 4nnrB-4r0xA:
40.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 10 TYR A  57
ASP A  68
ILE A  87
TYR A 113
PHE A 130
 None
 0.77A 4odoA-4r0xA:
11.8		 4odoA-4r0xA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 10 TYR A  57
ASP A  68
ILE A  87
TYR A 113
PHE A 130
 None
 0.74A 4odoB-4r0xA:
11.4		 4odoB-4r0xA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 10 TYR A  57
ASP A  68
ILE A  87
TYR A 113
PHE A 130
 None
 0.73A 4odoC-4r0xA:
11.2		 4odoC-4r0xA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 12 TYR A  57
ASP A  68
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 4odrA-4r0xA:
13.2
4odrB-4r0xA:
13.1		 4odrA-4r0xA:
23.36
4odrB-4r0xA:
23.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 10 TYR A  57
ASP A  68
PHE A  77
VAL A  86
TRP A  90
PHE A 130
 None
 0.68A 4qt2A-4r0xA:
22.1		 4qt2A-4r0xA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.64A 4qt2A-4r0xA:
22.1		 4qt2A-4r0xA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.75A 4qt3A-4r0xA:
20.9		 4qt3A-4r0xA:
49.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 10 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 4qt3A-4r0xA:
20.9		 4qt3A-4r0xA:
49.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 12 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.85A 5b8iC-4r0xA:
18.4		 5b8iC-4r0xA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.88A 5b8iC-4r0xA:
18.4		 5b8iC-4r0xA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 5d75A-4r0xA:
19.1		 5d75A-4r0xA:
37.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 5d75A-4r0xA:
19.1		 5d75A-4r0xA:
37.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 11 TYR A  57
ASP A  68
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.75A 5gpgA-4r0xA:
19.7		 5gpgA-4r0xA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.64A 5gpgA-4r0xA:
19.7		 5gpgA-4r0xA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.82A 5hkgA-4r0xA:
18.9		 5hkgA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 5hkgA-4r0xA:
18.9		 5hkgA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.68A 5huaA-4r0xA:
21.4		 5huaA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.80A 5huaA-4r0xA:
21.4		 5huaA-4r0xA:
43.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
 None
 0.81A 5hw8A-4r0xA:
17.7
5hw8D-4r0xA:
17.7		 5hw8A-4r0xA:
40.00
5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
 None
 0.86A 5hw8A-4r0xA:
17.7
5hw8D-4r0xA:
17.7		 5hw8A-4r0xA:
40.00
5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.75A 5hw8B-4r0xA:
17.7		 5hw8B-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
TRP A  90
TYR A 113
PHE A 130
 None
 0.79A 5hw8B-4r0xA:
17.7		 5hw8B-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 10 TYR A  57
ASP A  68
ARG A  73
VAL A  86
ILE A  87
TRP A  90
TYR A 113
LEU A 128
PHE A 130
 None
 0.87A 5hw8C-4r0xA:
17.6
5hw8H-4r0xA:
14.6		 5hw8C-4r0xA:
40.00
5hw8H-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.77A 5hw8D-4r0xA:
17.7		 5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
ILE A  87
TYR A 113
PHE A 130
 None
 0.84A 5hw8D-4r0xA:
17.7		 5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
ILE A 122
 None
 0.85A 5hw8D-4r0xA:
17.7		 5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 11 TYR A  57
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.71A 5hw8D-4r0xA:
17.7		 5hw8D-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.72A 5hw8E-4r0xA:
17.7		 5hw8E-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
ILE A 122
 None
 1.06A 5hw8E-4r0xA:
17.7		 5hw8E-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 11 TYR A  57
ASP A  68
ARG A  73
PHE A  77
PHE A 130
 None
 0.80A 5hw8E-4r0xA:
17.7		 5hw8E-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		6 / 12 TYR A  57
ASP A  68
PHE A  77
ILE A  87
TYR A 113
PHE A 130
 None
 0.79A 5hw8B-4r0xA:
17.7
5hw8F-4r0xA:
14.4
5hw8G-4r0xA:
17.5		 5hw8B-4r0xA:
40.00
5hw8F-4r0xA:
40.00
5hw8G-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		7 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.55A 5hw8B-4r0xA:
17.7
5hw8F-4r0xA:
14.4
5hw8G-4r0xA:
17.5		 5hw8B-4r0xA:
40.00
5hw8F-4r0xA:
40.00
5hw8G-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
ASP A  68
PHE A  77
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.82A 5hw8G-4r0xA:
17.5		 5hw8G-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 11 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 5hw8G-4r0xA:
17.5		 5hw8G-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		4 / 8 TYR A  57
ASP A  68
PHE A  77
ILE A 122
 None
 0.89A 5hw8H-4r0xA:
14.6		 5hw8H-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		4 / 8 TYR A  57
ASP A  68
PHE A  77
PHE A 130
 None
 0.60A 5hw8H-4r0xA:
14.6		 5hw8H-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 8 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
 None
 0.57A 5hw8H-4r0xA:
14.6		 5hw8H-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		5 / 8 TYR A  57
PHE A  77
VAL A  86
TRP A  90
PHE A 130
 None
 0.72A 5hw8H-4r0xA:
14.6		 5hw8H-4r0xA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
ARG A  73
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.77A 5hwcA-4r0xA:
19.7		 5hwcA-4r0xA:
47.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		9 / 11 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.72A 5hwcA-4r0xA:
19.7		 5hwcA-4r0xA:
47.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		4 / 8 LEU A 106
THR A  26
ILE A  92
ALA A  89
 None
 0.81A 5te8B-4r0xA:
undetectable		 5te8B-4r0xA:
14.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
PHE A 130
 None
 0.72A 6mkeA-4r0xA:
21.8
6mkeD-4r0xA:
21.8		 6mkeA-4r0xA:
47.50
6mkeD-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TYR A 113
PHE A 130
 None
 0.83A 6mkeA-4r0xA:
21.8
6mkeD-4r0xA:
21.8		 6mkeA-4r0xA:
47.50
6mkeD-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
ASP A  68
PHE A  77
VAL A  86
ILE A  87
TYR A 113
ILE A 122
PHE A 130
 None
 0.86A 6mkeA-4r0xA:
21.8
6mkeD-4r0xA:
21.8		 6mkeA-4r0xA:
47.50
6mkeD-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		8 / 12 TYR A  57
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.73A 6mkeA-4r0xA:
21.8
6mkeD-4r0xA:
21.8		 6mkeA-4r0xA:
47.50
6mkeD-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		10 / 12 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.79A 6mkeB-4r0xA:
22.0
6mkeC-4r0xA:
21.8		 6mkeB-4r0xA:
47.50
6mkeC-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		10 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.76A 6mkeC-4r0xA:
21.8		 6mkeC-4r0xA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4r0x PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens) 		10 / 10 TYR A  57
ASP A  68
ARG A  73
PHE A  77
VAL A  86
ILE A  87
TRP A  90
TYR A 113
ILE A 122
PHE A 130
 None
 0.80A 6mkeD-4r0xA:
21.8		 6mkeD-4r0xA:
47.50