SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E9L_A_GCSA800_1 (YM1 SECRETORY PROTEIN)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 9	GLY A 431 ASP A 127 GLN A 254 ASP A 240 TRP A 291	None	1.26A	1e9lA-4r12A: undetectable	1e9lA-4r12A: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	PHE A 299 TRP A 286 GLU A 289	None	1.01A	1mogA-4r12A: undetectable	1mogA-4r12A: 9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_E_FUAE706_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	THR A 387 SER A 386 TYR A 383 PHE A 257 VAL A 265	None	1.49A	1q23E-4r12A: undetectable	1q23E-4r12A: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UDU_B_CIAB2003_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 12	ILE A 456 ILE A 341 ALA A 284 PHE A 285 LEU A 527	None	1.07A	1uduB-4r12A: undetectable	1uduB-4r12A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_B_DVAB6_0 (GRAMICIDIN D)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	TRP A 291 ALA A 566 VAL A 213	None	0.95A	1w5uA-4r12A: undetectable 1w5uB-4r12A: undetectable	1w5uA-4r12A: 2.43 1w5uB-4r12A: 2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YC2_A_NCAA506_0 (NAD-DEPENDENT DEACETYLASE 2)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 6	ALA A 380 PHE A 390 ILE A 448 ASP A 447	None	0.89A	1yc2A-4r12A: undetectable	1yc2A-4r12A: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YC2_D_NCAD510_0 (NAD-DEPENDENT DEACETYLASE 2)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 5	ALA A 380 PHE A 390 ILE A 448 ASP A 447	None	0.77A	1yc2D-4r12A: undetectable	1yc2D-4r12A: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZGY_A_BRLA503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 5	ILE A 418 ILE A 266 ILE A 448 LEU A 234	None	0.86A	1zgyA-4r12A: undetectable	1zgyA-4r12A: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_A_DVAA6_0 (GRAMICIDIN D)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	ALA A 566 VAL A 213 TRP A 291	None	0.86A	2izqA-4r12A: undetectable 2izqB-4r12A: undetectable	2izqA-4r12A: 2.43 2izqB-4r12A: 2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_A_SAMA500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 6	THR A 419 ASP A 253 ASN A 439 ASP A 436	None	1.27A	2okcA-4r12A: undetectable	2okcA-4r12A: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W9S_E_TOPE1160_1 (DIHYDROFOLATE REDUCTASE TYPE 1 FROM TN4003)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 8	ILE A 346 ALA A 349 ILE A 448 PHE A 257	None	0.83A	2w9sE-4r12A: undetectable	2w9sE-4r12A: 14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BEX_A_PAUA248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	VAL A 440 GLY A 347 ASP A 253 THR A 481 THR A 261	None	1.38A	3bexA-4r12A: undetectable 3bexB-4r12A: undetectable	3bexA-4r12A: 17.59 3bexB-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BEX_C_PAUC248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	VAL A 440 GLY A 347 ASP A 253 THR A 481 THR A 261	None	1.38A	3bexC-4r12A: undetectable 3bexD-4r12A: undetectable	3bexC-4r12A: 17.59 3bexD-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BEX_F_PAUF248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	THR A 481 THR A 261 VAL A 440 GLY A 347 ASP A 253	None	1.38A	3bexE-4r12A: undetectable 3bexF-4r12A: undetectable	3bexE-4r12A: 17.59 3bexF-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BF1_A_PAUA248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	VAL A 440 GLY A 347 ASP A 253 THR A 481 THR A 261	None	1.35A	3bf1A-4r12A: undetectable 3bf1B-4r12A: undetectable	3bf1A-4r12A: 17.59 3bf1B-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BF1_C_PAUC248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	VAL A 440 GLY A 347 ASP A 253 THR A 481 THR A 261	None	1.31A	3bf1C-4r12A: undetectable 3bf1D-4r12A: undetectable	3bf1C-4r12A: 17.59 3bf1D-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BF1_E_PAUE248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	VAL A 440 GLY A 347 ASP A 253 THR A 481 THR A 261	None	1.37A	3bf1E-4r12A: undetectable 3bf1F-4r12A: undetectable	3bf1E-4r12A: 17.59 3bf1F-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BF1_F_PAUF248_0 (TYPE III PANTOTHENATE KINASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	THR A 481 THR A 261 VAL A 440 GLY A 347 ASP A 253	None	1.36A	3bf1E-4r12A: undetectable 3bf1F-4r12A: undetectable	3bf1E-4r12A: 17.59 3bf1F-4r12A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_2 (CYTOCHROME P450 2R1)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	LEU A 262 GLU A 342 ILE A 341	None	0.60A	3czhA-4r12A: undetectable	3czhA-4r12A: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_B_DVAB6_0 (GRAMICIDIN D)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	TRP A 291 ALA A 566 VAL A 213	None	0.93A	3l8lA-4r12A: undetectable 3l8lB-4r12A: undetectable	3l8lA-4r12A: 2.43 3l8lB-4r12A: 2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDR_A_GJZA506_1 (CHOLESTEROL 24-HYDROXYLASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 6	PHE A 455 ILE A 341 THR A 364 THR A 369	None	1.09A	3mdrA-4r12A: undetectable	3mdrA-4r12A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_B_9PLB501_1 (CYTOCHROME P450 2E1)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 6	LEU A 441 ALA A 258 THR A 261 LEU A 360	None	0.89A	3t3zB-4r12A: undetectable	3t3zB-4r12A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFG_B_LEUB289_0 (GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	PHE A 571 SER A 48 SER A 201	None	0.93A	3ufgB-4r12A: undetectable	3ufgB-4r12A: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UG8_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	TYR A 503 GLU A 289 TYR A 293	None	0.75A	3ug8A-4r12A: undetectable	3ug8A-4r12A: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGA_A_ACTA1131_0 (LYSOZYME C)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	ASN A 427 ASP A 435 ASN A 439	None	0.44A	4agaA-4r12A: undetectable	4agaA-4r12A: 12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA503_0 (OXIDOREDUCTASE, FMN-BINDING)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 6	SER A 217 TYR A 298 TRP A 286 PHE A 299	None	1.30A	4awuA-4r12A: undetectable	4awuA-4r12A: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EVR_A_BEZA401_0 (PUTATIVE ABC TRANSPORTER SUBUNIT, SUBSTRATE-BINDING COMPONENT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	LEU A 527 ALA A 270 PHE A 222 SER A 220 PHE A 283	None	1.49A	4evrA-4r12A: undetectable	4evrA-4r12A: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNV_A_QI9A602_0 (CYTOCHROME P450 2D6)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 9	LEU A 398 GLU A 342 SER A 405 VAL A 415 LEU A 234	None	1.16A	4wnvA-4r12A: undetectable	4wnvA-4r12A: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WS0_A_URFA301_1 (URACIL-DNA GLYCOSYLASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 7	GLY A 215 GLN A 216 SER A 504 ASN A 287	None	0.97A	4ws0A-4r12A: undetectable	4ws0A-4r12A: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WS1_A_URFA301_1 (URACIL-DNA GLYCOSYLASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 8	GLY A 215 GLN A 216 SER A 504 ASN A 287	None	0.96A	4ws1A-4r12A: undetectable	4ws1A-4r12A: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_C_REAC602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	ILE A 161 GLY A 111 LEU A 191 PHE A 245 LEU A 65	None	0.99A	5fhzC-4r12A: undetectable	5fhzC-4r12A: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA304_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 4	ARG A 246 THR A 153 GLY A 53 PHE A 52	None	1.43A	5uunA-4r12A: 0.0	5uunA-4r12A: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UXD_A_ZITA501_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E MPHH)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 7	ALA A 243 GLY A 431 TYR A 432 TYR A 429	None	0.94A	5uxdA-4r12A: undetectable	5uxdA-4r12A: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6L_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 9	ALA A 599 ASP A 192 LYS A 57 ILE A 161 PRO A 158	None	1.50A	5z6lA-4r12A: undetectable	5z6lA-4r12A: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 12	PRO A 126 VAL A 114 GLN A 434 PRO A 41 ILE A 161	None	1.41A	6becA-4r12A: undetectable 6becB-4r12A: undetectable 6becC-4r12A: undetectable	6becA-4r12A: 22.90 6becB-4r12A: 22.90 6becC-4r12A: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	3 / 3	PRO A 547 SER A 548 SER A 549	None	0.53A	6bpyA-4r12A: 1.2	6bpyA-4r12A: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	LEU A 205 SER A 201 ASP A 49 SER A 585 GLY A 570	None	1.48A	6dlzA-4r12A: undetectable 6dlzD-4r12A: undetectable	6dlzA-4r12A: 8.53 6dlzD-4r12A: 8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	SER A 585 GLY A 570 LEU A 205 SER A 201 ASP A 49	None	1.49A	6dlzB-4r12A: 2.1 6dlzC-4r12A: undetectable	6dlzB-4r12A: 8.53 6dlzC-4r12A: 8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	LEU A 205 SER A 201 ASP A 49 SER A 585 GLY A 570	None	1.49A	6dm1A-4r12A: undetectable 6dm1D-4r12A: undetectable	6dm1A-4r12A: 8.53 6dm1D-4r12A: 8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	SER A 585 GLY A 570 LEU A 205 SER A 201 ASP A 49	None	1.49A	6dm1B-4r12A: undetectable 6dm1C-4r12A: undetectable	6dm1B-4r12A: 8.53 6dm1C-4r12A: 8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ELI_A_T27A701_1 (REVERSE TRANSCRIPTASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 12	PRO A 212 LEU A 567 PRO A 321 LEU A 511 TYR A 298	None	1.43A	6eliA-4r12A: undetectable	6eliA-4r12A: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_B_SAMB301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 12	ILE A 233 ILE A 375 VAL A 379 ASP A 457 ILE A 459	None	1.06A	6emuB-4r12A: 1.9	6emuB-4r12A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_1 (TYROSINE-PROTEIN KINASE ABL1)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 5	VAL A 100 PHE A 194 MET A 195 GLY A 197	None	1.11A	6hd4A-4r12A: undetectable	6hd4A-4r12A: 9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_1 (TYROSINE-PROTEIN KINASE ABL1)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	4 / 5	VAL A 114 PHE A 194 MET A 195 GLY A 197	None	1.34A	6hd4A-4r12A: undetectable	6hd4A-4r12A: 9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_I_PCFI101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 11	ASP A 150 GLY A 251 SER A 255 ALA A 258 ASN A 146	None	1.41A	6hu9A-4r12A: 1.5 6hu9E-4r12A: undetectable 6hu9I-4r12A: undetectable	6hu9A-4r12A: 22.33 6hu9E-4r12A: 17.30 6hu9I-4r12A: 7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	4r12	PUTATIVE UNCHARACTERIZED PROTEIN (Dictyostelium purpureum)	5 / 10	ASP A 150 GLY A 251 SER A 255 ALA A 258 ASN A 146	None	1.48A	6hu9L-4r12A: undetectable 6hu9P-4r12A: undetectable 6hu9T-4r12A: undetectable	6hu9L-4r12A: 22.33 6hu9P-4r12A: 17.30 6hu9T-4r12A: 7.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E9L_A_GCSA800_1","YM1 SECRETORY PROTEIN","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"GLY A 431;ASP A 127;GLN A 254;ASP A 240;TRP A 291","None","1.26A","1e9lA-4r12A:undetectable","1e9lA-4r12A:20.34"],["1MOG_A_RBFA200_1","DODECIN","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"PHE A 299;TRP A 286;GLU A 289","None","1.01A","1mogA-4r12A:undetectable","1mogA-4r12A:9.34"],["1Q23_E_FUAE706_1","CHLORAMPHENICOL ACETYLTRANSFERASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"THR A 387;SER A 386;TYR A 383;PHE A 257;VAL A 265","None","1.49A","1q23E-4r12A:undetectable","1q23E-4r12A:16.35"],["1UDU_B_CIAB2003_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ILE A 456;ILE A 341;ALA A 284;PHE A 285;LEU A 527","None","1.07A","1uduB-4r12A:undetectable","1uduB-4r12A:19.25"],["1W5U_B_DVAB6_0","GRAMICIDIN D","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"TRP A 291;ALA A 566;VAL A 213","None","0.95A","1w5uA-4r12A:undetectable;1w5uB-4r12A:undetectable","1w5uA-4r12A:2.43;1w5uB-4r12A:2.43"],["1YC2_A_NCAA506_0","NAD-DEPENDENT DEACETYLASE 2","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ALA A 380;PHE A 390;ILE A 448;ASP A 447","None","0.89A","1yc2A-4r12A:undetectable","1yc2A-4r12A:16.50"],["1YC2_D_NCAD510_0","NAD-DEPENDENT DEACETYLASE 2","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ALA A 380;PHE A 390;ILE A 448;ASP A 447","None","0.77A","1yc2D-4r12A:undetectable","1yc2D-4r12A:16.50"],["1ZGY_A_BRLA503_2","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ILE A 418;ILE A 266;ILE A 448;LEU A 234","None","0.86A","1zgyA-4r12A:undetectable","1zgyA-4r12A:19.12"],["2IZQ_A_DVAA6_0","GRAMICIDIN D","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"ALA A 566;VAL A 213;TRP A 291","None","0.86A","2izqA-4r12A:undetectable;2izqB-4r12A:undetectable","2izqA-4r12A:2.43;2izqB-4r12A:2.43"],["2OKC_A_SAMA500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"THR A 419;ASP A 253;ASN A 439;ASP A 436","None","1.27A","2okcA-4r12A:undetectable","2okcA-4r12A:21.57"],["2W9S_E_TOPE1160_1","DIHYDROFOLATE REDUCTASE TYPE 1 FROM TN4003","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ILE A 346;ALA A 349;ILE A 448;PHE A 257","None","0.83A","2w9sE-4r12A:undetectable","2w9sE-4r12A:14.23"],["3BEX_A_PAUA248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"VAL A 440;GLY A 347;ASP A 253;THR A 481;THR A 261","None","1.38A","3bexA-4r12A:undetectable;3bexB-4r12A:undetectable","3bexA-4r12A:17.59;3bexB-4r12A:17.59"],["3BEX_C_PAUC248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"VAL A 440;GLY A 347;ASP A 253;THR A 481;THR A 261","None","1.38A","3bexC-4r12A:undetectable;3bexD-4r12A:undetectable","3bexC-4r12A:17.59;3bexD-4r12A:17.59"],["3BEX_F_PAUF248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"THR A 481;THR A 261;VAL A 440;GLY A 347;ASP A 253","None","1.38A","3bexE-4r12A:undetectable;3bexF-4r12A:undetectable","3bexE-4r12A:17.59;3bexF-4r12A:17.59"],["3BF1_A_PAUA248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"VAL A 440;GLY A 347;ASP A 253;THR A 481;THR A 261","None","1.35A","3bf1A-4r12A:undetectable;3bf1B-4r12A:undetectable","3bf1A-4r12A:17.59;3bf1B-4r12A:17.59"],["3BF1_C_PAUC248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"VAL A 440;GLY A 347;ASP A 253;THR A 481;THR A 261","None","1.31A","3bf1C-4r12A:undetectable;3bf1D-4r12A:undetectable","3bf1C-4r12A:17.59;3bf1D-4r12A:17.59"],["3BF1_E_PAUE248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"VAL A 440;GLY A 347;ASP A 253;THR A 481;THR A 261","None","1.37A","3bf1E-4r12A:undetectable;3bf1F-4r12A:undetectable","3bf1E-4r12A:17.59;3bf1F-4r12A:17.59"],["3BF1_F_PAUF248_0","TYPE III PANTOTHENATE KINASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"THR A 481;THR A 261;VAL A 440;GLY A 347;ASP A 253","None","1.36A","3bf1E-4r12A:undetectable;3bf1F-4r12A:undetectable","3bf1E-4r12A:17.59;3bf1F-4r12A:17.59"],["3CZH_A_D2VA602_2","CYTOCHROME P450 2R1","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"LEU A 262;GLU A 342;ILE A 341","None","0.60A","3czhA-4r12A:undetectable","3czhA-4r12A:21.73"],["3L8L_B_DVAB6_0","GRAMICIDIN D","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"TRP A 291;ALA A 566;VAL A 213","None","0.93A","3l8lA-4r12A:undetectable;3l8lB-4r12A:undetectable","3l8lA-4r12A:2.43;3l8lB-4r12A:2.63"],["3MDR_A_GJZA506_1","CHOLESTEROL 24-HYDROXYLASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"PHE A 455;ILE A 341;THR A 364;THR A 369","None","1.09A","3mdrA-4r12A:undetectable","3mdrA-4r12A:20.00"],["3T3Z_B_9PLB501_1","CYTOCHROME P450 2E1","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"LEU A 441;ALA A 258;THR A 261;LEU A 360","None","0.89A","3t3zB-4r12A:undetectable","3t3zB-4r12A:21.52"],["3UFG_B_LEUB289_0","GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"PHE A 571;SER A  48;SER A 201","None","0.93A","3ufgB-4r12A:undetectable","3ufgB-4r12A:19.66"],["3UG8_A_IMNA2001_2","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"TYR A 503;GLU A 289;TYR A 293","None","0.75A","3ug8A-4r12A:undetectable","3ug8A-4r12A:20.21"],["4AGA_A_ACTA1131_0","LYSOZYME C","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"ASN A 427;ASP A 435;ASN A 439","None","0.44A","4agaA-4r12A:undetectable","4agaA-4r12A:12.82"],["4AWU_A_4CHA503_0","OXIDOREDUCTASE, FMN-BINDING","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"SER A 217;TYR A 298;TRP A 286;PHE A 299","None","1.30A","4awuA-4r12A:undetectable","4awuA-4r12A:20.20"],["4EVR_A_BEZA401_0","PUTATIVE ABC TRANSPORTER SUBUNIT, SUBSTRATE-BINDING COMPONENT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"LEU A 527;ALA A 270;PHE A 222;SER A 220;PHE A 283","None","1.49A","4evrA-4r12A:undetectable","4evrA-4r12A:20.56"],["4WNV_A_QI9A602_0","CYTOCHROME P450 2D6","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"LEU A 398;GLU A 342;SER A 405;VAL A 415;LEU A 234","None","1.16A","4wnvA-4r12A:undetectable","4wnvA-4r12A:20.16"],["4WS0_A_URFA301_1","URACIL-DNA GLYCOSYLASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"GLY A 215;GLN A 216;SER A 504;ASN A 287","None","0.97A","4ws0A-4r12A:undetectable","4ws0A-4r12A:16.50"],["4WS1_A_URFA301_1","URACIL-DNA GLYCOSYLASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"GLY A 215;GLN A 216;SER A 504;ASN A 287","None","0.96A","4ws1A-4r12A:undetectable","4ws1A-4r12A:16.50"],["5FHZ_C_REAC602_1","ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ILE A 161;GLY A 111;LEU A 191;PHE A 245;LEU A  65","None","0.99A","5fhzC-4r12A:undetectable","5fhzC-4r12A:20.68"],["5UUN_A_ACTA304_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ARG A 246;THR A 153;GLY A  53;PHE A  52","None","1.43A","5uunA-4r12A:0.0","5uunA-4r12A:18.86"],["5UXD_A_ZITA501_1","MACROLIDE 2'-PHOSPHOTRANSFERASE MPHH","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"ALA A 243;GLY A 431;TYR A 432;TYR A 429","None","0.94A","5uxdA-4r12A:undetectable","5uxdA-4r12A:15.94"],["5Z6L_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ALA A 599;ASP A 192;LYS A  57;ILE A 161;PRO A 158","None","1.50A","5z6lA-4r12A:undetectable","5z6lA-4r12A:14.76"],["6BEC_C_RBTC601_1","SCAFFOLD PROTEIN D13;SCAFFOLD PROTEIN D13;SCAFFOLD PROTEIN D13","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"PRO A 126;VAL A 114;GLN A 434;PRO A  41;ILE A 161","None","1.41A","6becA-4r12A:undetectable;6becB-4r12A:undetectable;6becC-4r12A:undetectable","6becA-4r12A:22.90;6becB-4r12A:22.90;6becC-4r12A:22.90"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",3,"PRO A 547;SER A 548;SER A 549","None","0.53A","6bpyA-4r12A:1.2","6bpyA-4r12A:19.38"],["6DLZ_A_CYZA1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"LEU A 205;SER A 201;ASP A  49;SER A 585;GLY A 570","None","1.48A","6dlzA-4r12A:undetectable;6dlzD-4r12A:undetectable","6dlzA-4r12A:8.53;6dlzD-4r12A:8.53"],["6DLZ_C_CYZC1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"SER A 585;GLY A 570;LEU A 205;SER A 201;ASP A  49","None","1.49A","6dlzB-4r12A:2.1;6dlzC-4r12A:undetectable","6dlzB-4r12A:8.53;6dlzC-4r12A:8.53"],["6DM1_A_CYZA1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"LEU A 205;SER A 201;ASP A  49;SER A 585;GLY A 570","None","1.49A","6dm1A-4r12A:undetectable;6dm1D-4r12A:undetectable","6dm1A-4r12A:8.53;6dm1D-4r12A:8.53"],["6DM1_C_CYZC1302_0","GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"SER A 585;GLY A 570;LEU A 205;SER A 201;ASP A  49","None","1.49A","6dm1B-4r12A:undetectable;6dm1C-4r12A:undetectable","6dm1B-4r12A:8.53;6dm1C-4r12A:8.53"],["6ELI_A_T27A701_1","REVERSE TRANSCRIPTASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"PRO A 212;LEU A 567;PRO A 321;LEU A 511;TYR A 298","None","1.43A","6eliA-4r12A:undetectable","6eliA-4r12A:8.70"],["6EMU_B_SAMB301_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ILE A 233;ILE A 375;VAL A 379;ASP A 457;ILE A 459","None","1.06A","6emuB-4r12A:1.9","6emuB-4r12A:17.86"],["6HD4_A_STIA604_1","TYROSINE-PROTEIN KINASE ABL1","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"VAL A 100;PHE A 194;MET A 195;GLY A 197","None","1.11A","6hd4A-4r12A:undetectable","6hd4A-4r12A:9.19"],["6HD4_A_STIA604_1","TYROSINE-PROTEIN KINASE ABL1","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",4,"VAL A 114;PHE A 194;MET A 195;GLY A 197","None","1.34A","6hd4A-4r12A:undetectable","6hd4A-4r12A:9.19"],["6HU9_I_PCFI101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ASP A 150;GLY A 251;SER A 255;ALA A 258;ASN A 146","None","1.41A","6hu9A-4r12A:1.5;6hu9E-4r12A:undetectable;6hu9I-4r12A:undetectable","6hu9A-4r12A:22.33;6hu9E-4r12A:17.30;6hu9I-4r12A:7.76"],["6HU9_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","4r12","PUTATIVE UNCHARACTERIZED PROTEIN","Dictyostelium purpureum",5,"ASP A 150;GLY A 251;SER A 255;ALA A 258;ASN A 146","None","1.48A","6hu9L-4r12A:undetectable;6hu9P-4r12A:undetectable;6hu9T-4r12A:undetectable","6hu9L-4r12A:22.33;6hu9P-4r12A:17.30;6hu9T-4r12A:7.76"]]