SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 THR A 477
GLY A 465
ASP A 461
TYR A 467
 None
 0.96A 1bu5A-4r1dA:
3.7		 1bu5A-4r1dA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 THR A 477
GLY A 465
ASP A 461
TYR A 467
 None
 0.92A 1bu5B-4r1dA:
3.5		 1bu5B-4r1dA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 137
ASN A  61
GLY A 117
VAL A 304
 None
 0.87A 1dbbH-4r1dA:
undetectable
1dbbL-4r1dA:
undetectable		 1dbbH-4r1dA:
17.02
1dbbL-4r1dA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 453
LEU A 341
ARG A 357
ILE A 478
GLY A 465
 None
 1.24A 1g50B-4r1dA:
undetectable		 1g50B-4r1dA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 GLU A 453
LEU A 341
ARG A 357
ILE A 478
GLY A 465
 None
 1.24A 1g50C-4r1dA:
undetectable		 1g50C-4r1dA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 539
GLY A 280
VAL A 261
PHE A  53
 None
 1.05A 1gsfA-4r1dA:
undetectable		 1gsfA-4r1dA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 539
GLY A 280
VAL A 261
PHE A  53
 None
 1.05A 1gsfB-4r1dA:
undetectable		 1gsfB-4r1dA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 539
GLY A 280
VAL A 261
PHE A  53
 None
 1.05A 1gsfD-4r1dA:
undetectable		 1gsfD-4r1dA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 SER B 215
THR B 216
GLU A 104
GLY B  64
 None
 1.16A 1icrA-4r1dB:
undetectable
1icrB-4r1dB:
undetectable		 1icrA-4r1dB:
21.19
1icrB-4r1dB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 104
GLY B  64
SER B 215
THR B 216
 None
 1.15A 1icrA-4r1dA:
undetectable
1icrB-4r1dA:
undetectable		 1icrA-4r1dA:
16.76
1icrB-4r1dA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 SER B 215
THR B 216
GLU A 104
GLY B  64
 None
 1.15A 1icuA-4r1dB:
undetectable
1icuB-4r1dB:
undetectable		 1icuA-4r1dB:
21.19
1icuB-4r1dB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 104
GLY B  64
SER B 215
THR B 216
 None
 1.15A 1icuA-4r1dA:
undetectable
1icuB-4r1dA:
undetectable		 1icuA-4r1dA:
16.76
1icuB-4r1dA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 SER B 215
THR B 216
GLU A 104
GLY B  64
 None
 1.16A 1icvC-4r1dB:
undetectable
1icvD-4r1dB:
undetectable		 1icvC-4r1dB:
21.19
1icvD-4r1dB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 104
GLY B  64
SER B 215
THR B 216
 None
 1.16A 1icvC-4r1dA:
undetectable
1icvD-4r1dA:
undetectable		 1icvC-4r1dA:
16.76
1icvD-4r1dA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		4 / 5 GLU A 104
GLY B  64
SER B 215
THR B 216
 None
 1.17A 1kqbA-4r1dA:
undetectable
1kqbB-4r1dA:
undetectable		 1kqbA-4r1dA:
16.87
1kqbB-4r1dA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		4 / 6 SER B 215
THR B 216
GLU A 104
GLY B  64
 None
 1.16A 1kqbC-4r1dB:
undetectable
1kqbD-4r1dB:
undetectable		 1kqbC-4r1dB:
21.01
1kqbD-4r1dB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		4 / 6 GLU A 104
GLY B  64
SER B 215
THR B 216
 None
 1.16A 1kqbC-4r1dA:
undetectable
1kqbD-4r1dA:
undetectable		 1kqbC-4r1dA:
16.87
1kqbD-4r1dA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 169
ALA A 166
ASP A 170
GLU A 171
 None
 1.48A 1lqtA-4r1dA:
2.4
1lqtB-4r1dA:
undetectable		 1lqtA-4r1dA:
22.30
1lqtB-4r1dA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 169
ALA A 166
ASP A 170
GLU A 171
 None
 1.50A 1lquA-4r1dA:
undetectable
1lquB-4r1dA:
undetectable		 1lquA-4r1dA:
22.30
1lquB-4r1dA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 309
GLY A 307
GLN A 385
MET A 389
LEU B 220
 None
 1.21A 1p93C-4r1dA:
undetectable		 1p93C-4r1dA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.26A 1uw6A-4r1dA:
undetectable
1uw6B-4r1dA:
undetectable		 1uw6A-4r1dA:
17.54
1uw6B-4r1dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.24A 1uw6D-4r1dA:
undetectable
1uw6E-4r1dA:
undetectable		 1uw6D-4r1dA:
17.54
1uw6E-4r1dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.23A 1uw6G-4r1dA:
undetectable
1uw6H-4r1dA:
undetectable		 1uw6G-4r1dA:
17.54
1uw6H-4r1dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.23A 1uw6P-4r1dA:
undetectable
1uw6Q-4r1dA:
undetectable		 1uw6P-4r1dA:
17.54
1uw6Q-4r1dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TRP A 445
TYR A 467
TRP A 375
THR A 374
 None
 1.23A 1uw6P-4r1dA:
undetectable
1uw6T-4r1dA:
undetectable		 1uw6P-4r1dA:
17.54
1uw6T-4r1dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 502
GLU A 182
HIS A 519
 None
 0.88A 1xwfA-4r1dA:
undetectable		 1xwfA-4r1dA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 502
GLU A 182
HIS A 519
 None
 0.85A 1xwfB-4r1dA:
undetectable		 1xwfB-4r1dA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 502
GLU A 182
HIS A 519
 None
 0.86A 1xwfC-4r1dA:
undetectable		 1xwfC-4r1dA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 502
GLU A 182
HIS A 519
 None
 0.88A 1xwfD-4r1dA:
undetectable		 1xwfD-4r1dA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 PRO A  99
GLY A 307
ASN A 309
GLY A 311
 None
 0.81A 1zlqA-4r1dA:
undetectable		 1zlqA-4r1dA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 197
TYR A 200
ARG A 196
TYR A 428
 None
 1.02A 2ajvH-4r1dA:
undetectable
2ajvL-4r1dA:
undetectable		 2ajvH-4r1dA:
16.58
2ajvL-4r1dA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 441
SER A 494
ARG A 336
GLN A 506
 None
 1.27A 2c8aA-4r1dA:
undetectable		 2c8aA-4r1dA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  49
VAL A 277
HIS A 424
ALA A 207
VAL A 274
 None
 1.26A 2g70A-4r1dA:
undetectable		 2g70A-4r1dA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  49
VAL A 277
HIS A 424
ALA A 207
VAL A 274
 None
 1.25A 2g70B-4r1dA:
undetectable		 2g70B-4r1dA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  49
VAL A 277
HIS A 424
ALA A 207
VAL A 274
 None
 1.25A 2g72B-4r1dA:
undetectable		 2g72B-4r1dA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 255
PHE A  53
TYR A 539
ALA A 544
PRO A 146
 None
 1.23A 2igtC-4r1dA:
undetectable		 2igtC-4r1dA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 SER A 124
GLY A 149
ASP A 114
ASP A 120
 None
 1.00A 2oxtB-4r1dA:
undetectable		 2oxtB-4r1dA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 THR A 556
ILE A 189
LEU A 155
LEU A 194
ILE A 158
 None
 1.38A 3a50B-4r1dA:
undetectable		 3a50B-4r1dA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 150
VAL A 204
ILE A 251
LEU A 549
ILE A 553
 None
 1.14A 3ijdB-4r1dA:
undetectable		 3ijdB-4r1dA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		5 / 12 GLU A 104
GLY B  64
ASP A 388
GLY B 217
SER B 215
 None
 1.23A 3k13A-4r1dA:
undetectable		 3k13A-4r1dA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		5 / 12 GLU A 104
GLY B  64
ASP A 388
GLY B 217
SER B 215
 None
 1.25A 3k13B-4r1dA:
undetectable		 3k13B-4r1dA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		5 / 12 GLU A 104
GLY B  64
ASP A 388
GLY B 217
SER B 215
 None
 1.26A 3k13C-4r1dA:
undetectable		 3k13C-4r1dA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 532
TYR A 533
GLY A 432
ASP A 497
 None
 1.32A 3kl3A-4r1dA:
undetectable		 3kl3A-4r1dA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 GLY B  64
GLN A 110
GLU A 104
LEU B  62
ILE B  67
 None
 1.20A 3kvrA-4r1dB:
undetectable		 3kvrA-4r1dB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 GLY B  64
GLN A 110
GLU A 104
LEU B  62
ILE B  67
 None
 1.29A 3kvrB-4r1dB:
undetectable		 3kvrB-4r1dB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 279
TYR A 423
ALA A 262
GLY A 286
SER A 329
 None
 1.02A 3ln1A-4r1dA:
undetectable		 3ln1A-4r1dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 279
TYR A 423
ALA A 262
GLY A 286
SER A 329
 None
 1.01A 3ln1B-4r1dA:
undetectable		 3ln1B-4r1dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 279
TYR A 423
ALA A 262
GLY A 286
SER A 329
 None
 1.01A 3ln1C-4r1dA:
undetectable		 3ln1C-4r1dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 GLU A 334
TYR A 431
ARG A 336
ASP A 490
 None
 0.92A 3mjrD-4r1dA:
2.4		 3mjrD-4r1dA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 144
VAL A 139
GLY A  59
GLY A 208
 None
 0.81A 3n9jB-4r1dA:
undetectable		 3n9jB-4r1dA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 GLY B  64
GLN A 110
GLU A 104
LEU B  62
ILE B  67
 None
 1.26A 3nbqA-4r1dB:
undetectable		 3nbqA-4r1dB:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 431
ASP A 497
ASP A 541
 None
 1.00A 3ou7B-4r1dA:
undetectable		 3ou7B-4r1dA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 147
ILE A  52
VAL A 230
ARG A 134
TYR A 234
 None
None
None
CA  A 601 ( 4.6A)
None
 1.35A 3p6gA-4r1dA:
undetectable		 3p6gA-4r1dA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  52
VAL A 230
ARG A 134
TYR A 234
 None
None
CA  A 601 ( 4.6A)
None
 1.01A 3p6hA-4r1dA:
undetectable		 3p6hA-4r1dA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 503
ILE A 444
ASP A 442
ARG A 441
ASP A 490
 None
 1.50A 3phaA-4r1dA:
undetectable		 3phaA-4r1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ASP A 461
GLY A 377
ILE A 369
ILE A 444
ILE A 478
 None
 1.12A 3s56B-4r1dA:
undetectable		 3s56B-4r1dA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 535
ASP A 497
GLY A  56
SER A 256
SER A 142
 None
 1.22A 3sueD-4r1dA:
undetectable		 3sueD-4r1dA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 512
GLN A 183
SER A 504
GLU A 181
ALA A 429
 None
 1.41A 3t7sC-4r1dA:
undetectable		 3t7sC-4r1dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 503
ILE A 444
ASP A 442
ARG A 441
ASP A 490
 None
 1.47A 3w37A-4r1dA:
undetectable		 3w37A-4r1dA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 555
ILE A 226
VAL A 230
LEU A 231
PHE A 233
 None
 1.10A 3w67B-4r1dA:
2.3		 3w67B-4r1dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 503
ILE A 444
ASP A 442
ARG A 441
ASP A 490
 None
 1.48A 3welA-4r1dA:
undetectable		 3welA-4r1dA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.28A 3wipD-4r1dA:
undetectable
3wipE-4r1dA:
undetectable		 3wipD-4r1dA:
18.94
3wipE-4r1dA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A  72
VAL A 139
TRP A 211
 None
 1.50A 3zq8A-4r1dA:
undetectable
3zq8B-4r1dA:
undetectable		 3zq8A-4r1dA:
3.56
3zq8B-4r1dA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 211
VAL A 139
TRP A  72
 None
 1.46A 3zq8A-4r1dA:
undetectable
3zq8B-4r1dA:
undetectable		 3zq8A-4r1dA:
3.56
3zq8B-4r1dA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 346
ARG A 441
ILE A 444
LEU A 349
 None
 1.01A 4acbC-4r1dA:
2.7		 4acbC-4r1dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 531
GLY A 432
ASP A 497
GLY A 495
 None
 0.89A 4koeA-4r1dA:
undetectable
4koeB-4r1dA:
undetectable
4koeC-4r1dA:
3.8		 4koeA-4r1dA:
20.96
4koeB-4r1dA:
20.96
4koeC-4r1dA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 531
GLY A 432
ASP A 497
GLY A 495
 None
 0.93A 4koeA-4r1dA:
undetectable
4koeB-4r1dA:
undetectable
4koeD-4r1dA:
3.7		 4koeA-4r1dA:
20.96
4koeB-4r1dA:
20.96
4koeD-4r1dA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 VAL B 261
ALA B 262
GLY A  89
SER B 264
GLY B 270
 None
 1.29A 4mmdA-4r1dB:
undetectable		 4mmdA-4r1dB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASP B 128
TYR B 130
TRP B  88
 None
 1.13A 4p7nA-4r1dB:
undetectable		 4p7nA-4r1dB:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_C_PARC500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 SER A 439
THR A 502
SER A 494
GLU A 182
GLY A 432
 None
 1.44A 4qb9C-4r1dA:
undetectable		 4qb9C-4r1dA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 SER A 439
THR A 502
SER A 494
GLU A 182
GLY A 432
 None
 1.43A 4qb9E-4r1dA:
undetectable		 4qb9E-4r1dA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 THR A 289
GLY A 496
GLY A 495
ASP A 442
 None
 0.79A 4qvvK-4r1dA:
undetectable
4qvvL-4r1dA:
undetectable		 4qvvK-4r1dA:
18.37
4qvvL-4r1dA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 THR A 289
GLY A 496
GLY A 495
ASP A 442
 None
 0.79A 4qvvY-4r1dA:
undetectable
4qvvZ-4r1dA:
undetectable		 4qvvY-4r1dA:
18.37
4qvvZ-4r1dA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 156
LEU A 155
GLU A 237
PHE A 233
LEU A 126
 CA  A 601 (-2.3A)
None
None
None
None
 1.11A 4retA-4r1dA:
2.0		 4retA-4r1dA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 180
GLN A 179
TYR A 533
ASN A 528
 None
 1.08A 4ws0A-4r1dA:
3.0		 4ws0A-4r1dA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 432
ASP A 497
GLY A 495
ARG A 531
 None
 0.99A 4z53A-4r1dA:
2.0
4z53B-4r1dA:
2.2		 4z53A-4r1dA:
21.39
4z53B-4r1dA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 370
GLY A 286
TYR A 366
GLY A 416
 None
 0.94A 5ayfA-4r1dA:
undetectable		 5ayfA-4r1dA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 GLU A 453
LEU A 341
ARG A 357
ILE A 478
GLY A 465
 None
 1.24A 5dxbB-4r1dA:
undetectable		 5dxbB-4r1dA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 453
LEU A 341
ARG A 357
ILE A 478
GLY A 465
 None
 1.19A 5gs4A-4r1dA:
undetectable		 5gs4A-4r1dA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PRO A  55
GLY A 137
ASP A 115
MET A 140
ALA A 143
 None
 1.00A 5h5fA-4r1dA:
1.8		 5h5fA-4r1dA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 279
LEU A 418
TYR A 423
ALA A 262
GLY A 286
 None
 1.00A 5jw1B-4r1dA:
undetectable		 5jw1B-4r1dA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA407_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 503
THR A 502
GLN A 506
ARG A 518
 None
 1.27A 5k9dA-4r1dA:
undetectable		 5k9dA-4r1dA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 279
VAL A 281
TYR A 533
HIS A 519
 None
 1.50A 5kkzA-4r1dA:
undetectable
5kkzG-4r1dA:
undetectable		 5kkzA-4r1dA:
21.47
5kkzG-4r1dA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.30A 5kxiA-4r1dA:
undetectable
5kxiB-4r1dA:
undetectable		 5kxiA-4r1dA:
19.79
5kxiB-4r1dA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 467
TRP A 375
THR A 374
TRP A 445
 None
 1.32A 5kxiD-4r1dA:
undetectable
5kxiE-4r1dA:
undetectable		 5kxiD-4r1dA:
19.79
5kxiE-4r1dA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 SER A 256
THR A 289
SER A 287
THR A 499
 None
 0.98A 5l4eA-4r1dA:
undetectable
5l4eB-4r1dA:
undetectable
5l4eC-4r1dA:
undetectable
5l4eD-4r1dA:
0.6
5l4eE-4r1dA:
0.6		 5l4eA-4r1dA:
19.55
5l4eB-4r1dA:
19.55
5l4eC-4r1dA:
19.55
5l4eD-4r1dA:
19.55
5l4eE-4r1dA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 4r1d UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		4 / 7 GLY B  59
PHE B 196
ARG A  63
ASN B  57
 None
 0.92A 5n5dB-4r1dB:
undetectable		 5n5dB-4r1dB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOC_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 TRP B 142
VAL B 193
ARG B 150
TRP B  63
 None
 1.47A 5uocA-4r1dB:
0.0
5uocB-4r1dB:
0.0		 5uocA-4r1dB:
22.69
5uocB-4r1dB:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 147
ASN A 145
GLY A 135
VAL A 204
CYH A 206
 None
 1.19A 6czmD-4r1dA:
undetectable
6czmE-4r1dA:
undetectable		 6czmD-4r1dA:
21.56
6czmE-4r1dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 VAL A 147
ASN A 145
GLY A 135
VAL A 204
CYH A 206
 None
 1.17A 6czmE-4r1dA:
undetectable
6czmF-4r1dA:
undetectable		 6czmE-4r1dA:
21.56
6czmF-4r1dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4r1d UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ASP B  34
HIS B 205
GLU B 204
ASP B  53
 None
 1.28A 6mn4B-4r1dB:
undetectable		 6mn4B-4r1dB:
22.25