SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 4r1s CINNAMOYL COA
REDUCTASE
(Petunia
x
hybrida) 		4 / 8 GLN A  94
LEU A  66
ARG A  38
SER A  86
 None
NAP  A 401 ( 4.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.8A)
 0.93A 1hk3A-4r1sA:
undetectable		 1hk3A-4r1sA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4r1s CINNAMOYL COA
REDUCTASE
(Petunia
x
hybrida) 		5 / 11 ILE A 107
ILE A  75
ALA A 113
ALA A 111
VAL A 177
 None
 0.95A 2qhfA-4r1sA:
undetectable		 2qhfA-4r1sA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4r1s CINNAMOYL COA
REDUCTASE
(Petunia
x
hybrida) 		4 / 5 VAL A 301
TYR A 221
VAL A 256
ASP A 255
 None
 1.34A 2x45A-4r1sA:
undetectable		 2x45A-4r1sA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4r1s CINNAMOYL COA
REDUCTASE
(Petunia
x
hybrida) 		5 / 12 VAL A  33
LEU A  27
VAL A  37
GLY A  13
ALA A  14
 None
None
None
NAP  A 401 ( 3.9A)
None
 1.08A 3ln1D-4r1sA:
undetectable		 3ln1D-4r1sA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4r1s CINNAMOYL COA
REDUCTASE
(Petunia
x
hybrida) 		4 / 8 SER A 123
ASN A 183
ARG A 243
GLY A 160
 NAP  A 401 ( 3.1A)
None
None
None
 0.90A 4af0A-4r1sA:
undetectable		 4af0A-4r1sA:
21.02