SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4r2m UNIVERSAL STRESS
PROTEIN F
(Salmonella
enterica) 		5 / 10 PHE A  37
ILE A  76
ILE A  21
SER A  22
LEU A  81
 None
 1.26A 3o1cA-4r2mA:
undetectable		 3o1cA-4r2mA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 4r2m UNIVERSAL STRESS
PROTEIN F
(Salmonella
enterica) 		5 / 12 ALA A 136
VAL A 111
LEU A   6
VAL A 142
VAL A 140
 None
 0.72A 6dh0B-4r2mA:
undetectable		 6dh0B-4r2mA:
19.75