SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
THR A  91
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 1jdvA-4r2wA:
31.2
1jdvD-4r2wA:
31.1		 1jdvA-4r2wA:
33.85
1jdvD-4r2wA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
THR A  91
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 1jdvB-4r2wA:
31.1
1jdvC-4r2wA:
30.8		 1jdvB-4r2wA:
33.85
1jdvC-4r2wA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
THR A  91
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 1jdvA-4r2wA:
31.2
1jdvD-4r2wA:
31.1		 1jdvA-4r2wA:
33.85
1jdvD-4r2wA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ARG A  27
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
SO4  A 302 (-3.0A)
 1.28A 1jdvE-4r2wA:
31.2
1jdvF-4r2wA:
30.7		 1jdvE-4r2wA:
33.85
1jdvF-4r2wA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 12 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 1jdvE-4r2wA:
31.2
1jdvF-4r2wA:
30.7		 1jdvE-4r2wA:
33.85
1jdvF-4r2wA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.36A 1odiA-4r2wA:
25.0		 1odiA-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.33A 1odiA-4r2wA:
25.0		 1odiA-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.26A 1odiB-4r2wA:
32.6		 1odiB-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.30A 1odiB-4r2wA:
32.6		 1odiB-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.26A 1odiC-4r2wA:
32.7		 1odiC-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.30A 1odiC-4r2wA:
32.7		 1odiC-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.33A 1odiD-4r2wA:
32.5		 1odiD-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.30A 1odiD-4r2wA:
32.5		 1odiD-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.34A 1odiE-4r2wA:
32.7		 1odiE-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.32A 1odiE-4r2wA:
32.7		 1odiE-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.36A 1odiF-4r2wA:
32.4		 1odiF-4r2wA:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.31A 1odiF-4r2wA:
32.4		 1odiF-4r2wA:
32.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 5 LEU A   6
MET A  12
LEU A  13
GLN A  80
 None
 0.90A 1p93D-4r2wA:
undetectable		 1p93D-4r2wA:
22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 9 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.26A 1pk7A-4r2wA:
31.0		 1pk7A-4r2wA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.25A 1pk7C-4r2wA:
31.4		 1pk7C-4r2wA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.26A 1pk9A-4r2wA:
31.0		 1pk9A-4r2wA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 9 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.28A 1pk9B-4r2wA:
31.0		 1pk9B-4r2wA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.34A 1pk9C-4r2wA:
31.4		 1pk9C-4r2wA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.45A 1pw7A-4r2wA:
31.1		 1pw7A-4r2wA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.27A 1pw7A-4r2wA:
31.1		 1pw7A-4r2wA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 9 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.37A 1pw7B-4r2wA:
31.5		 1pw7B-4r2wA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.21A 1rxcB-4r2wA:
43.4		 1rxcB-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.44A 1rxcC-4r2wA:
43.4		 1rxcC-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.33A 1rxcD-4r2wA:
43.4		 1rxcD-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.27A 1rxcE-4r2wA:
43.6		 1rxcE-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.21A 1rxcF-4r2wA:
43.6		 1rxcF-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.22A 1rxcI-4r2wA:
43.6		 1rxcI-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.20A 1rxcK-4r2wA:
43.7		 1rxcK-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.21A 1rxcL-4r2wA:
43.6		 1rxcL-4r2wA:
75.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ARG A  27
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
SO4  A 302 (-3.0A)
 1.28A 1vhwA-4r2wA:
31.6
1vhwD-4r2wA:
31.6		 1vhwA-4r2wA:
27.41
1vhwD-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.40A 1vhwA-4r2wA:
31.6
1vhwD-4r2wA:
31.6		 1vhwA-4r2wA:
27.41
1vhwD-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.37A 1vhwA-4r2wA:
31.6
1vhwD-4r2wA:
31.6		 1vhwA-4r2wA:
27.41
1vhwD-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ARG A  27
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
SO4  A 302 (-3.0A)
 1.28A 1vhwC-4r2wA:
31.7
1vhwE-4r2wA:
31.5		 1vhwC-4r2wA:
27.41
1vhwE-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.46A 1vhwC-4r2wA:
31.7
1vhwE-4r2wA:
31.5		 1vhwC-4r2wA:
27.41
1vhwE-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.28A 1vhwA-4r2wA:
31.6
1vhwD-4r2wA:
31.6		 1vhwA-4r2wA:
27.41
1vhwD-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.44A 1vhwA-4r2wA:
31.6
1vhwD-4r2wA:
31.6		 1vhwA-4r2wA:
27.41
1vhwD-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.28A 1vhwC-4r2wA:
31.7
1vhwE-4r2wA:
31.5		 1vhwC-4r2wA:
27.41
1vhwE-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.40A 1vhwC-4r2wA:
31.7
1vhwE-4r2wA:
31.5		 1vhwC-4r2wA:
27.41
1vhwE-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.36A 1vhwC-4r2wA:
31.7
1vhwE-4r2wA:
31.5		 1vhwC-4r2wA:
27.41
1vhwE-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.29A 1vhwB-4r2wA:
31.6
1vhwF-4r2wA:
31.8		 1vhwB-4r2wA:
27.41
1vhwF-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.37A 1vhwB-4r2wA:
31.6
1vhwF-4r2wA:
31.8		 1vhwB-4r2wA:
27.41
1vhwF-4r2wA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 5 SER A 110
SER A 196
THR A 153
ASN A 191
 None
 1.31A 1yvpA-4r2wA:
2.8		 1yvpA-4r2wA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 6 SER A 110
ALA A 197
SER A 196
THR A 153
 None
 0.82A 1yvpB-4r2wA:
2.8		 1yvpB-4r2wA:
17.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 10 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.43A 1z35A-4r2wA:
31.2		 1z35A-4r2wA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 9 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.34A 1z37A-4r2wA:
31.2		 1z37A-4r2wA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ARG A  27
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
SO4  A 302 (-3.0A)
 1.34A 2ac7A-4r2wA:
30.0
2ac7B-4r2wA:
30.0		 2ac7A-4r2wA:
34.23
2ac7B-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 2ac7A-4r2wA:
30.0
2ac7B-4r2wA:
30.0		 2ac7A-4r2wA:
34.23
2ac7B-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.32A 2ac7A-4r2wA:
30.0
2ac7B-4r2wA:
30.0		 2ac7A-4r2wA:
34.23
2ac7B-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.29A 2ac7A-4r2wA:
30.0
2ac7B-4r2wA:
30.0		 2ac7A-4r2wA:
34.23
2ac7B-4r2wA:
34.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 7 SER A 110
ALA A 197
SER A 196
THR A 153
 None
 0.79A 2i91A-4r2wA:
undetectable		 2i91A-4r2wA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 7 SER A 110
ALA A 197
SER A 196
THR A 153
 None
 0.80A 2i91B-4r2wA:
undetectable		 2i91B-4r2wA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 THR A  71
ALA A  74
GLU A  77
LEU A  78
LEU A   6
 None
 0.86A 2jfaA-4r2wA:
undetectable		 2jfaA-4r2wA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 6 TYR A  53
ALA A  52
LEU A  51
ALA A  16
THR A  17
 None
 1.33A 3b6hA-4r2wA:
undetectable		 3b6hA-4r2wA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 PHE A 159
GLN A 163
ARG A 165
MET A 194
ILE A 225
 None
None
None
GOL  A 303 (-3.5A)
None
 1.20A 3kvrA-4r2wA:
25.8		 3kvrA-4r2wA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 10 THR A  91
GLY A  93
PHE A 159
GLN A 163
ARG A 165
GLU A 193
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
 0.30A 3kvrA-4r2wA:
25.8		 3kvrA-4r2wA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 PHE A 159
GLN A 163
ARG A 165
MET A 194
ILE A 225
 None
None
None
GOL  A 303 (-3.5A)
None
 1.25A 3kvrB-4r2wA:
25.7		 3kvrB-4r2wA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 10 THR A  91
GLY A  93
PHE A 159
GLN A 163
ARG A 165
GLU A 193
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
 0.29A 3kvrB-4r2wA:
25.7		 3kvrB-4r2wA:
27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.24A 3kvvA-4r2wA:
42.9		 3kvvA-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.28A 3kvvB-4r2wA:
42.7		 3kvvB-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.32A 3kvvC-4r2wA:
42.9		 3kvvC-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.32A 3kvvD-4r2wA:
42.7		 3kvvD-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.27A 3kvvE-4r2wA:
42.4		 3kvvE-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.22A 3kvvF-4r2wA:
20.4		 3kvvF-4r2wA:
75.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 9 THR A  91
GLY A  93
GLN A 163
ARG A 165
GLU A 193
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
 0.31A 3nbqA-4r2wA:
25.7		 3nbqA-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.36A 3nbqB-4r2wA:
25.6		 3nbqB-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.28A 3nbqC-4r2wA:
25.5		 3nbqC-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 9 GLN A 163
ARG A 165
MET A 194
ARG A 220
ILE A 225
 None
None
GOL  A 303 (-3.5A)
None
None
 1.16A 3nbqD-4r2wA:
25.7		 3nbqD-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 9 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ARG A 220
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
 0.45A 3nbqD-4r2wA:
25.7		 3nbqD-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 GLY A  90
GLY A  23
LEU A  18
VAL A 242
ALA A 245
 SO4  A 302 (-3.3A)
SO4  A 302 (-3.2A)
None
None
None
 1.24A 3t7vA-4r2wA:
undetectable		 3t7vA-4r2wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.25A 3u40B-4r2wA:
29.7
3u40C-4r2wA:
13.7		 3u40B-4r2wA:
27.69
3u40C-4r2wA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.23A 3u40B-4r2wA:
29.7
3u40C-4r2wA:
13.7		 3u40B-4r2wA:
27.69
3u40C-4r2wA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ARG A  27
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
SO4  A 302 (-3.0A)
 1.29A 3u40D-4r2wA:
29.9
3u40E-4r2wA:
30.3		 3u40D-4r2wA:
27.69
3u40E-4r2wA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.22A 3u40D-4r2wA:
29.9
3u40E-4r2wA:
30.3		 3u40D-4r2wA:
27.69
3u40E-4r2wA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.23A 3u40D-4r2wA:
29.9
3u40E-4r2wA:
30.3		 3u40D-4r2wA:
27.69
3u40E-4r2wA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.27A 3u40D-4r2wA:
29.9
3u40E-4r2wA:
30.3		 3u40D-4r2wA:
27.69
3u40E-4r2wA:
27.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.32A 3uawA-4r2wA:
30.7		 3uawA-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 10 ARG A  88
GLY A  93
GLU A 193
GLU A 195
ILE A  95
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
None
 1.41A 3uayA-4r2wA:
30.5		 3uayA-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 10 ARG A  88
THR A  91
GLY A  93
GLU A 193
MET A 194
GLU A 195
 SO4  A 302 ( 2.8A)
SO4  A 302 ( 3.0A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
 0.31A 3uayA-4r2wA:
30.5		 3uayA-4r2wA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
VAL A 218
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.33A 4d9hA-4r2wA:
30.0		 4d9hA-4r2wA:
30.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 10 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
VAL A 218
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.30A 4da7A-4r2wA:
29.8		 4da7A-4r2wA:
30.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 11 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
VAL A 218
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.36A 4danA-4r2wA:
29.3		 4danA-4r2wA:
30.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 ARG A  27
ARG A  88
GLY A  93
GLU A 193
GLU A 195
 SO4  A 302 (-3.0A)
SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-2.9A)
 1.29A 4danA-4r2wA:
29.3
4danB-4r2wA:
29.6		 4danA-4r2wA:
30.80
4danB-4r2wA:
30.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 12 ARG A  88
GLY A  93
GLU A 193
MET A 194
GLU A 195
VAL A 218
 SO4  A 302 ( 2.8A)
None
GOL  A 303 (-4.9A)
GOL  A 303 (-3.5A)
GOL  A 303 (-2.9A)
None
 1.32A 4danA-4r2wA:
29.3
4danB-4r2wA:
29.6		 4danA-4r2wA:
30.80
4danB-4r2wA:
30.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.28A 4e1vA-4r2wA:
43.0		 4e1vA-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		7 / 7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.27A 4e1vB-4r2wA:
43.4		 4e1vB-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.29A 4e1vC-4r2wA:
43.0		 4e1vC-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.26A 4e1vD-4r2wA:
43.4		 4e1vD-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.24A 4e1vE-4r2wA:
43.5		 4e1vE-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
 None
None
None
GOL  A 303 (-3.5A)
None
None
 0.23A 4e1vF-4r2wA:
43.1		 4e1vF-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.38A 4e1vG-4r2wA:
41.2		 4e1vG-4r2wA:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		8 / 8 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
None
None
None
 0.31A 4e1vH-4r2wA:
42.6		 4e1vH-4r2wA:
75.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		3 / 3 ASP A 114
TRP A 208
SER A 110
 None
 0.94A 4lrhA-4r2wA:
undetectable		 4lrhA-4r2wA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		4 / 6 ASP A  36
ASN A  37
ALA A  52
ASP A  55
 None
 1.19A 4mdaA-4r2wA:
undetectable		 4mdaA-4r2wA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 SER A 196
THR A  91
THR A  92
ALA A 214
THR A  71
 None
SO4  A 302 ( 3.0A)
None
None
None
 1.13A 4qvnV-4r2wA:
undetectable
4qvnb-4r2wA:
undetectable		 4qvnV-4r2wA:
23.02
4qvnb-4r2wA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 SER A 196
THR A  91
THR A  92
ALA A 214
THR A  71
 None
SO4  A 302 ( 3.0A)
None
None
None
 1.12A 4qvnH-4r2wA:
undetectable
4qvnN-4r2wA:
undetectable		 4qvnH-4r2wA:
23.02
4qvnN-4r2wA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 7 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.31A 4txnA-4r2wA:
24.8		 4txnA-4r2wA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 7 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.30A 4txnB-4r2wA:
24.8		 4txnB-4r2wA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 7 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.31A 4txnC-4r2wA:
24.8		 4txnC-4r2wA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 7 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.31A 4txnD-4r2wA:
24.8		 4txnD-4r2wA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 12 GLY A  67
GLU A 195
GLY A  65
GLY A  23
SER A  70
ALA A 116
 None
GOL  A 303 (-2.9A)
None
SO4  A 302 (-3.2A)
None
None
 1.30A 4uciA-4r2wA:
undetectable		 4uciA-4r2wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 12 GLY A  67
GLU A 195
GLY A  65
GLY A  23
SER A  70
ALA A 116
 None
GOL  A 303 (-2.9A)
None
SO4  A 302 (-3.2A)
None
None
 1.30A 4uciB-4r2wA:
undetectable		 4uciB-4r2wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		6 / 12 GLY A  67
GLU A 195
GLY A  65
GLY A  23
SER A  70
ALA A 116
 None
GOL  A 303 (-2.9A)
None
SO4  A 302 (-3.2A)
None
None
 1.26A 4uckA-4r2wA:
undetectable		 4uckA-4r2wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		3 / 3 VAL A 216
VAL A 101
GLN A 222
 None
 0.65A 5qgmA-4r2wA:
undetectable		 5qgmA-4r2wA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 SER A 196
THR A  91
THR A  92
ALA A 214
THR A  71
 None
SO4  A 302 ( 3.0A)
None
None
None
 1.06A 6hwdV-4r2wA:
undetectable
6hwdb-4r2wA:
undetectable		 6hwdV-4r2wA:
20.75
6hwdb-4r2wA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4r2w URIDINE
PHOSPHORYLASE
(Shewanella
oneidensis) 		5 / 12 SER A 196
THR A  91
THR A  92
ALA A 214
THR A  71
 None
SO4  A 302 ( 3.0A)
None
None
None
 1.06A 6hwdH-4r2wA:
undetectable
6hwdN-4r2wA:
undetectable		 6hwdH-4r2wA:
20.75
6hwdN-4r2wA:
17.84