SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 4r30 LAFORIN
(Homo
sapiens) 		3 / 3 ALA A 275
VAL A 249
TRP A 280
 BME  A 503 ( 4.5A)
None
None
 0.90A 1c4dC-4r30A:
undetectable
1c4dD-4r30A:
undetectable		 1c4dC-4r30A:
7.80
1c4dD-4r30A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 4r30 LAFORIN
(Homo
sapiens) 		3 / 3 TRP A 280
ALA A 275
VAL A 249
 None
BME  A 503 ( 4.5A)
None
 0.75A 1c4dC-4r30A:
undetectable
1c4dD-4r30A:
undetectable		 1c4dC-4r30A:
7.80
1c4dD-4r30A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 4r30 LAFORIN
(Homo
sapiens) 		3 / 3 PHE A 192
ARG A 171
ASN A 267
 None
None
SO4  A 501 (-4.6A)
 0.87A 1xzxX-4r30A:
undetectable		 1xzxX-4r30A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4r30 LAFORIN
(Homo
sapiens) 		3 / 3 TYR A 208
GLU A 223
THR A 177
 None
 1.03A 2y7hB-4r30A:
undetectable		 2y7hB-4r30A:
16.23