SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4r4k UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 THR A  51
PHE A  50
PHE A  43
LEU A 135
 None
None
ACT  A 202 ( 4.9A)
PEU  A 204 ( 4.0A)
 1.13A 1qcaA-4r4kA:
undetectable		 1qcaA-4r4kA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 4r4k UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 5 PHE A  46
PHE A  43
PHE A 114
VAL A 149
 None
ACT  A 202 ( 4.9A)
ACT  A 202 ( 4.4A)
None
 1.23A 2lh6A-4r4kA:
undetectable		 2lh6A-4r4kA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 4r4k UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 5 LEU A 161
GLN A 168
LEU A 166
GLU A 165
 None
 0.95A 3h5gA-4r4kA:
undetectable
3h5gB-4r4kA:
undetectable		 3h5gA-4r4kA:
12.99
3h5gB-4r4kA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4r4k UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 6 LEU A 161
GLN A 168
LEU A 166
GLU A 165
 None
 1.04A 3h5gB-4r4kA:
undetectable
3h5gC-4r4kA:
undetectable		 3h5gB-4r4kA:
12.99
3h5gC-4r4kA:
12.99