SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 GLY A  58
SER A  65
LEU A 230
GLY A 231
GLY A 232
 None
 0.89A 1uakA-4r72A:
undetectable		 1uakA-4r72A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		6 / 11 PHE A 295
ILE A 291
GLY A 227
ILE A 104
LEU A 230
PHE A  88
 None
 1.44A 1z11A-4r72A:
undetectable		 1z11A-4r72A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 PHE A 109
GLY A 200
TYR A 170
LEU A 107
LEU A 136
 None
 1.20A 1zgyA-4r72A:
undetectable		 1zgyA-4r72A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 7 PHE A 295
TYR A 293
THR A 153
GLY A 105
 None
 0.94A 2a1mA-4r72A:
undetectable		 2a1mA-4r72A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 THR A 197
ALA A 193
ALA A 215
GLY A 200
ALA A 189
 None
 1.00A 2f16K-4r72A:
undetectable
2f16L-4r72A:
undetectable		 2f16K-4r72A:
21.08
2f16L-4r72A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 THR A 197
ALA A 193
ALA A 215
GLY A 200
ALA A 189
 None
 1.00A 2f16Y-4r72A:
undetectable
2f16Z-4r72A:
undetectable		 2f16Y-4r72A:
21.08
2f16Z-4r72A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 ILE A 104
TYR A 228
ILE A 106
LEU A 288
LEU A 285
 None
None
None
GOL  A 404 (-3.9A)
None
 1.47A 3f78A-4r72A:
undetectable		 3f78A-4r72A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 ILE A 104
TYR A 228
ILE A 106
LEU A 288
LYS A  87
 None
None
None
GOL  A 404 (-3.9A)
None
 1.02A 3f78A-4r72A:
undetectable		 3f78A-4r72A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 ILE A 104
TYR A 228
ILE A 106
LEU A 288
LYS A  87
 None
None
None
GOL  A 404 (-3.9A)
None
 1.02A 3f78B-4r72A:
undetectable		 3f78B-4r72A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.25A 3fhjA-4r72A:
undetectable		 3fhjA-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.24A 3fhjB-4r72A:
undetectable		 3fhjB-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.25A 3fhjC-4r72A:
undetectable		 3fhjC-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.27A 3fhjE-4r72A:
undetectable		 3fhjE-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.24A 3fi0A-4r72A:
undetectable		 3fi0A-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.23A 3fi0C-4r72A:
undetectable		 3fi0C-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.17A 3fi0D-4r72A:
undetectable		 3fi0D-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.22A 3fi0F-4r72A:
undetectable		 3fi0F-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.28A 3fi0H-4r72A:
undetectable		 3fi0H-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.23A 3fi0J-4r72A:
undetectable		 3fi0J-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.22A 3fi0K-4r72A:
undetectable		 3fi0K-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.29A 3fi0L-4r72A:
undetectable		 3fi0L-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.26A 3fi0M-4r72A:
undetectable		 3fi0M-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.24A 3fi0N-4r72A:
undetectable		 3fi0N-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 9 GLN A  83
ASP A 250
VAL A 233
VAL A 102
GLN A 258
 None
 1.30A 3fi0O-4r72A:
undetectable		 3fi0O-4r72A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		3 / 3 SER A 148
GLY A 149
THR A 150
 GOL  A 402 (-2.5A)
GOL  A 402 (-4.0A)
GOL  A 402 (-3.7A)
 0.11A 3k9wA-4r72A:
undetectable		 3k9wA-4r72A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 7 GLY A  59
GLY A 105
PHE A 251
PHE A 248
 None
 0.94A 3ko0M-4r72A:
undetectable
3ko0P-4r72A:
undetectable		 3ko0M-4r72A:
16.67
3ko0P-4r72A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 PHE A 158
THR A 157
GLY A 108
GLY A 227
GLY A 202
 None
 0.87A 3tegA-4r72A:
undetectable		 3tegA-4r72A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 6 ILE A 155
VAL A 312
LEU A 317
ILE A 315
 None
 0.89A 4asdA-4r72A:
undetectable		 4asdA-4r72A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		3 / 3 GLY A  38
SER A  37
TRP A  56
 None
 0.94A 4e7cD-4r72A:
undetectable		 4e7cD-4r72A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 6 THR A 260
GLY A 265
ASN A  17
GLY A  58
 None
 0.88A 4fjpA-4r72A:
6.8		 4fjpA-4r72A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 GLY A 225
PHE A 158
LEU A 288
GLY A 108
LEU A 204
 None
None
GOL  A 404 (-3.9A)
None
None
 0.88A 4n48A-4r72A:
undetectable		 4n48A-4r72A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 GLY A 225
PHE A 158
LEU A 288
GLY A 108
LEU A 204
 None
None
GOL  A 404 (-3.9A)
None
None
 0.88A 4n48B-4r72A:
undetectable		 4n48B-4r72A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 THR A 197
ALA A 193
ALA A 215
GLY A 200
ALA A 189
 None
 1.00A 4qw1Y-4r72A:
undetectable
4qw1Z-4r72A:
undetectable		 4qw1Y-4r72A:
21.08
4qw1Z-4r72A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 GLY A 225
GLU A 224
LEU A 107
ALA A 154
ALA A 167
 None
 1.29A 4wnuD-4r72A:
undetectable		 4wnuD-4r72A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 5 ARG A 240
GLN A  52
PRO A  51
ASP A  54
 None
 1.39A 4z4hA-4r72A:
undetectable		 4z4hA-4r72A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		3 / 3 ALA A  18
GLN A 258
THR A 260
 None
 0.74A 5n0oA-4r72A:
undetectable		 5n0oA-4r72A:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 12 GLY A  58
SER A  65
LEU A 230
GLY A 231
GLY A 232
 None
 0.90A 5wyqB-4r72A:
undetectable		 5wyqB-4r72A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		5 / 10 ILE A 186
TRP A 262
ALA A 282
LEU A 268
ALA A 267
 GOL  A 401 (-4.6A)
None
None
None
None
 1.49A 5zjiB-4r72A:
undetectable		 5zjiB-4r72A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 5 GLU A 229
ASP A 206
HIS A 205
THR A 150
 None
None
None
GOL  A 402 (-3.7A)
 1.44A 6b58A-4r72A:
undetectable		 6b58A-4r72A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Actinobacillus
pleuropneumoniae) 		4 / 6 TRP A 262
ALA A 282
LEU A 268
ALA A 267
 None
 1.00A 6fosB-4r72A:
undetectable		 6fosB-4r72A:
13.83