SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4r7q SENSOR HISTIDINE
KINASE
(Vibrio
cholerae) 		5 / 12 ILE A  44
LEU A 234
ALA A 191
PHE A 199
SER A 197
 None
None
None
None
SO4  A 302 (-2.4A)
 1.46A 3apwB-4r7qA:
undetectable		 3apwB-4r7qA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r7q SENSOR HISTIDINE
KINASE
(Vibrio
cholerae) 		3 / 3 GLY A 136
SER A 135
TRP A 131
 None
 0.79A 4e7cD-4r7qA:
undetectable		 4e7cD-4r7qA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 4r7q SENSOR HISTIDINE
KINASE
(Vibrio
cholerae) 		4 / 7 SER A 135
PRO A 114
TYR A  86
PHE A 117
 None
 1.20A 5l1fC-4r7qA:
undetectable		 5l1fC-4r7qA:
14.55