SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
ARG A  52
GLU A 128
 None
 0.91A 2c8aB-4r7vA:
undetectable		 2c8aB-4r7vA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
SER A 126
GLU A 128
 None
 1.04A 2c8aB-4r7vA:
undetectable		 2c8aB-4r7vA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
ARG A  52
GLU A 128
 None
 0.93A 2c8aD-4r7vA:
undetectable		 2c8aD-4r7vA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
SER A 126
GLU A 128
 None
 1.04A 2c8aD-4r7vA:
undetectable		 2c8aD-4r7vA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A  52
ARG A 135
TRP A 137
 None
 1.15A 4cpzC-4r7vA:
undetectable		 4cpzC-4r7vA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A  52
ARG A 135
TRP A 137
 None
 1.07A 4cpzE-4r7vA:
undetectable		 4cpzE-4r7vA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A  52
ARG A 135
TRP A 137
 None
 1.13A 4cpzF-4r7vA:
undetectable		 4cpzF-4r7vA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A  52
ARG A 135
TRP A 137
 None
 1.09A 4cpzG-4r7vA:
undetectable		 4cpzG-4r7vA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A  52
ARG A 135
TRP A 137
 None
 1.19A 4cpzH-4r7vA:
undetectable		 4cpzH-4r7vA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 ALA A  51
ASP A  14
ARG A  33
GLU A 111
 None
 0.95A 5bs8A-4r7vA:
undetectable
5bs8B-4r7vA:
undetectable
5bs8C-4r7vA:
undetectable		 5bs8A-4r7vA:
15.81
5bs8B-4r7vA:
20.85
5bs8C-4r7vA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4r7v ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		5 / 9 VAL A   6
LEU A  36
VAL A  44
HIS A 143
ILE A  42
 None
 0.86A 5om2A-4r7vA:
undetectable
5om2B-4r7vA:
undetectable		 5om2A-4r7vA:
17.61
5om2B-4r7vA:
8.24