SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7x ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
SER A 126
GLU A 128
 None
 0.88A 2c8aB-4r7xA:
undetectable		 2c8aB-4r7xA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4r7x ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLY A  53
SER A 133
SER A 126
GLU A 128
 None
 0.87A 2c8aD-4r7xA:
undetectable		 2c8aD-4r7xA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4r7x ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		5 / 9 VAL A   6
LEU A  36
VAL A  44
HIS A 143
ILE A  42
 None
None
None
PO4  A 204 ( 3.9A)
None
 0.74A 5om2A-4r7xA:
undetectable
5om2B-4r7xA:
undetectable		 5om2A-4r7xA:
17.93
5om2B-4r7xA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 4r7x ARRESTIN
DOMAIN-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 6 ILE A  89
TYR A 112
LEU A  36
VAL A  44
 None
PO4  A 206 (-4.7A)
None
None
 1.26A 6f6jA-4r7xA:
undetectable		 6f6jA-4r7xA:
undetectable