SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 VAL A 460
ILE A 459
PHE A 458
TYR A 448
ILE A 451
 None
 1.07A 1c9hA-4r84A:
undetectable		 1c9hA-4r84A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 ASP A 242
TYR A 293
LEU A 300
ASP A 302
 None
 1.01A 1rmtD-4r84A:
2.6		 1rmtD-4r84A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 6 ALA A 441
PHE A 353
ILE A 378
VAL A 377
 None
 0.90A 2cizA-4r84A:
undetectable		 2cizA-4r84A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
PRO A 124
TYR A 276
TYR A 286
PHE A 288
 None
 1.05A 2h21B-4r84A:
undetectable		 2h21B-4r84A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
PRO A 124
TYR A 276
TYR A 286
PHE A 288
 None
 1.06A 2h21C-4r84A:
undetectable		 2h21C-4r84A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.94A 2obvA-4r84A:
undetectable		 2obvA-4r84A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.92A 2p02A-4r84A:
undetectable		 2p02A-4r84A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 HIS A 279
TYR A 286
LEU A 226
LEU A 250
TYR A 306
 None
 1.50A 2prgB-4r84A:
undetectable		 2prgB-4r84A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		3 / 3 SER A 147
HIS A 131
ASP A 285
 None
 0.81A 2wa2B-4r84A:
3.5		 2wa2B-4r84A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 ASP A  69
PHE A  75
LEU A  42
PHE A  77
ILE A  64
 None
 1.42A 3o94A-4r84A:
5.8		 3o94A-4r84A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 ASP A  69
PHE A  75
LEU A  42
PHE A  77
ILE A  64
 None
 1.48A 3o94B-4r84A:
5.8		 3o94B-4r84A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 ASP A  69
PHE A  75
LEU A  42
PHE A  77
ILE A  64
 None
 1.44A 3o94C-4r84A:
5.8		 3o94C-4r84A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 ASP A  69
PHE A  75
LEU A  42
PHE A  77
ILE A  64
 None
 1.43A 3o94D-4r84A:
5.8		 3o94D-4r84A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.01A 3qxyA-4r84A:
undetectable		 3qxyA-4r84A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 10 PHE A  90
GLY A  61
GLU A  86
VAL A  34
PHE A  77
 None
 1.38A 3r6wA-4r84A:
4.3
3r6wB-4r84A:
1.9		 3r6wA-4r84A:
17.69
3r6wB-4r84A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.05A 3rc0A-4r84A:
undetectable		 3rc0A-4r84A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.03A 3rc0B-4r84A:
undetectable		 3rc0B-4r84A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 1.02A 4kttA-4r84A:
undetectable		 4kttA-4r84A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.99A 4ndnA-4r84A:
undetectable		 4ndnA-4r84A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 7 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.97A 4ndnC-4r84A:
undetectable		 4ndnC-4r84A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 6 ASP A 285
TYR A 286
LEU A 226
HIS A 223
 None
 1.11A 4paeA-4r84A:
undetectable		 4paeA-4r84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		3 / 3 ASN A 104
PHE A  90
TYR A  40
 None
 0.78A 4u15A-4r84A:
undetectable		 4u15A-4r84A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.93A 5a1iA-4r84A:
undetectable		 5a1iA-4r84A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 7 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.93A 5a1iA-4r84A:
undetectable		 5a1iA-4r84A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 VAL A 178
THR A 197
ILE A 210
GLN A 211
PHE A 195
 None
 1.39A 5hgcA-4r84A:
undetectable		 5hgcA-4r84A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 VAL A 460
ILE A 459
PHE A 458
TYR A 448
ILE A 451
 None
 1.07A 5hkgA-4r84A:
undetectable		 5hkgA-4r84A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.44A 5iqdA-4r84A:
0.0		 5iqdA-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.43A 5iqdB-4r84A:
0.0		 5iqdB-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.39A 5iqdD-4r84A:
0.0		 5iqdD-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 5 ALA A 381
VAL A 377
PHE A 353
ILE A 443
 None
None
None
CSF  A 501 (-4.8A)
 0.83A 5of1A-4r84A:
undetectable		 5of1A-4r84A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 5 ALA A 381
VAL A 377
PHE A 353
ILE A 443
 None
None
None
CSF  A 501 (-4.8A)
 0.78A 5of1B-4r84A:
undetectable		 5of1B-4r84A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 TYR A 448
LEU A 485
GLY A 486
VAL A 493
ASP A 492
 None
 1.21A 6bxlA-4r84A:
undetectable		 6bxlA-4r84A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 10 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.39A 6c5uA-4r84A:
0.0		 6c5uA-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 9 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.41A 6c5uB-4r84A:
0.2		 6c5uB-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 10 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.40A 6c5uD-4r84A:
0.0		 6c5uD-4r84A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.94A 6fboA-4r84A:
undetectable		 6fboA-4r84A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.95A 6fcbA-4r84A:
undetectable		 6fcbA-4r84A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.93A 6fcdA-4r84A:
undetectable		 6fcdA-4r84A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4r84 SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 7 HIS A 120
ASP A 119
SER A 426
ASP A 229
 None
None
CSF  A 501 ( 3.8A)
None
 0.94A 6g6rA-4r84A:
undetectable		 6g6rA-4r84A:
21.54