SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		4 / 4 THR A 166
LEU A 165
VAL A 158
LEU A 157
 None
 0.94A 1mz9D-4r94A:
undetectable		 1mz9D-4r94A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		3 / 3 ASN A  32
ALA A 177
ASN A 150
 None
 0.67A 1n4fA-4r94A:
undetectable		 1n4fA-4r94A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		3 / 3 SER A  70
ASP A  91
CYH A 128
 None
 0.99A 2br4E-4r94A:
undetectable		 2br4E-4r94A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		4 / 7 LEU A  56
GLU A  53
TRP A 156
SER A  92
 None
 1.42A 3dzgA-4r94A:
undetectable		 3dzgA-4r94A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		4 / 6 LEU A  56
GLU A  53
TRP A 156
SER A  92
 None
 1.44A 3i9jB-4r94A:
undetectable		 3i9jB-4r94A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 12 LEU A  37
ILE A  42
CYH A 161
GLU A 169
LEU A 173
 None
 1.23A 3ko0G-4r94A:
0.5
3ko0H-4r94A:
0.6
3ko0I-4r94A:
0.7
3ko0J-4r94A:
0.7		 3ko0G-4r94A:
16.86
3ko0H-4r94A:
16.86
3ko0I-4r94A:
16.86
3ko0J-4r94A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 12 LEU A  37
ILE A  42
CYH A 161
GLU A 169
LEU A 173
 None
 1.19A 3ko0K-4r94A:
0.7
3ko0L-4r94A:
undetectable
3ko0S-4r94A:
undetectable
3ko0T-4r94A:
0.7		 3ko0K-4r94A:
16.86
3ko0L-4r94A:
16.86
3ko0S-4r94A:
16.86
3ko0T-4r94A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 12 LEU A  37
ILE A  42
CYH A 161
GLU A 169
LEU A 173
 None
 1.20A 3ko0M-4r94A:
undetectable
3ko0N-4r94A:
undetectable
3ko0O-4r94A:
undetectable
3ko0P-4r94A:
undetectable		 3ko0M-4r94A:
16.86
3ko0N-4r94A:
16.86
3ko0O-4r94A:
16.86
3ko0P-4r94A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 12 GLU A 169
LEU A 173
LEU A  37
ILE A  42
CYH A 161
 None
 1.24A 3ko0M-4r94A:
undetectable
3ko0N-4r94A:
undetectable
3ko0O-4r94A:
undetectable
3ko0P-4r94A:
undetectable		 3ko0M-4r94A:
16.86
3ko0N-4r94A:
16.86
3ko0O-4r94A:
16.86
3ko0P-4r94A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		4 / 6 LEU A  56
GLU A  53
TRP A 156
SER A  92
 None
 1.41A 3ropA-4r94A:
undetectable		 3ropA-4r94A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 12 LEU A 165
LEU A 173
LEU A 157
GLN A  86
ILE A  42
 None
 1.14A 4a7aB-4r94A:
undetectable		 4a7aB-4r94A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 9 ILE A 132
GLY A 133
PHE A 137
VAL A 101
GLN A 141
 None
 1.40A 4acaB-4r94A:
undetectable
4acaC-4r94A:
undetectable		 4acaB-4r94A:
18.80
4acaC-4r94A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		4 / 8 ARG A 146
GLU A 181
GLU A 178
ARG A 174
 None
 1.17A 4bqfB-4r94A:
undetectable		 4bqfB-4r94A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 11 GLY A 125
GLY A 121
GLY A 225
HIS A 118
GLN A 117
 None
 1.02A 4l8fB-4r94A:
undetectable		 4l8fB-4r94A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4r94 NON-STRUCTURAL
PROTEIN NS1
(Rodent
protoparvovirus
1) 		5 / 11 GLY A 125
GLY A 121
GLY A 225
HIS A 118
GLN A 117
 None
 0.94A 4l8fD-4r94A:
undetectable		 4l8fD-4r94A:
21.56