SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A 120
VAL A 261
ASN A 242
GLY A 208
 None
 0.93A 1dzmA-4r9nA:
undetectable		 1dzmA-4r9nA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ARG A 121
GLY A 117
THR A 217
ILE A 221
 None
 0.97A 2f9wA-4r9nA:
undetectable
2f9wB-4r9nA:
undetectable		 2f9wA-4r9nA:
22.65
2f9wB-4r9nA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A 115
GLY A 208
ASP A 249
ASP A 240
 None
 1.04A 2oxtB-4r9nA:
undetectable		 2oxtB-4r9nA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 310
LEU A 288
ALA A 277
VAL A 276
THR A 303
 None
 1.24A 2qo6A-4r9nA:
undetectable		 2qo6A-4r9nA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 217
ILE A 221
TYR A 223
GLY A 117
HIS A 152
 None
 1.31A 2y7kA-4r9nA:
undetectable		 2y7kA-4r9nA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 217
ILE A 221
TYR A 223
GLY A 117
HIS A 152
 None
 1.24A 2y7pA-4r9nA:
undetectable		 2y7pA-4r9nA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A  68
ARG A 305
MET A 306
ILE A 300
VAL A 238
 None
 1.13A 2ygnA-4r9nA:
undetectable		 2ygnA-4r9nA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ILE A 141
TYR A 223
MET A 218
THR A 217
 None
 1.49A 3abkN-4r9nA:
undetectable
3abkW-4r9nA:
undetectable		 3abkN-4r9nA:
17.97
3abkW-4r9nA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LEU A 264
ALA A 205
VAL A 275
PRO A 273
 None
 1.00A 3gv1B-4r9nA:
undetectable		 3gv1B-4r9nA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 11 LEU A 171
ASN A 154
SER A 153
LEU A 196
LEU A 264
 None
 1.29A 3ndvA-4r9nA:
undetectable
3ndvB-4r9nA:
undetectable		 3ndvA-4r9nA:
21.95
3ndvB-4r9nA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 11 LEU A 196
LEU A 264
LEU A 171
ASN A 154
SER A 153
 None
 1.29A 3ndvC-4r9nA:
undetectable
3ndvD-4r9nA:
undetectable		 3ndvC-4r9nA:
21.95
3ndvD-4r9nA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ASP A 298
LEU A  74
ALA A 294
LEU A 296
 None
 1.05A 3rozA-4r9nA:
undetectable		 3rozA-4r9nA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 302
ALA A 279
LEU A 112
MET A 204
LEU A 102
 None
 1.18A 3s79A-4r9nA:
undetectable		 3s79A-4r9nA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A 295
GLY A 250
LEU A 264
VAL A 275
ALA A 205
 None
 1.19A 3t7vA-4r9nA:
undetectable		 3t7vA-4r9nA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ASP A 304
THR A  61
LEU A  64
GLU A 308
 None
 1.26A 4a3pA-4r9nA:
undetectable		 4a3pA-4r9nA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A  78
GLU A  76
GLU A  65
LEU A  64
 None
 0.90A 4mj8A-4r9nA:
undetectable		 4mj8A-4r9nA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A 263
GLY A 199
ILE A 137
SER A 168
TYR A 170
 None
 1.04A 4rtmA-4r9nA:
undetectable		 4rtmA-4r9nA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 262
VAL A 261
GLY A 142
VAL A 275
LEU A 269
 None
 1.09A 5ergB-4r9nA:
2.2		 5ergB-4r9nA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 302
ALA A 279
LEU A 112
MET A 204
LEU A 102
 None
 1.20A 5jkvA-4r9nA:
undetectable		 5jkvA-4r9nA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 4r9n LMO0547 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 123
LEU A 278
ALA A  98
THR A 274
 None
 1.03A 6f88A-4r9nA:
undetectable		 6f88A-4r9nA:
14.90