SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 ASP A 242
TYR A 293
LEU A 300
ASP A 302
 None
 1.08A 1rmtD-4r9vA:
2.6		 1rmtD-4r9vA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 7 LEU A 123
ASP A 229
THR A 199
TYR A 227
 None
 1.16A 1v55C-4r9vA:
undetectable
1v55N-4r9vA:
undetectable
1v55P-4r9vA:
undetectable		 1v55C-4r9vA:
21.52
1v55N-4r9vA:
20.53
1v55P-4r9vA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 6 ALA A 441
PHE A 353
ILE A 378
VAL A 377
 None
 0.94A 2cizA-4r9vA:
undetectable		 2cizA-4r9vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
PRO A 124
TYR A 276
TYR A 286
PHE A 288
 None
 1.12A 2h21B-4r9vA:
undetectable		 2h21B-4r9vA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
PRO A 124
TYR A 276
TYR A 286
PHE A 288
 None
 1.14A 2h21C-4r9vA:
undetectable		 2h21C-4r9vA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		3 / 3 ASN A 204
ILE A 209
MET A 177
 None
 0.80A 2h42C-4r9vA:
undetectable		 2h42C-4r9vA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 363
ILE A 467
SER A 464
ALA A 473
ILE A 443
 None
 1.15A 2nnhA-4r9vA:
undetectable		 2nnhA-4r9vA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		3 / 3 SER A 147
HIS A 131
ASP A 285
 None
 0.80A 2wa2B-4r9vA:
3.1		 2wa2B-4r9vA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 LEU A 123
ASP A 229
THR A 199
TYR A 227
 None
 1.15A 3asoC-4r9vA:
undetectable
3asoN-4r9vA:
undetectable
3asoP-4r9vA:
undetectable		 3asoC-4r9vA:
21.52
3asoN-4r9vA:
20.53
3asoP-4r9vA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 7 VAL A 202
LEU A 226
TYR A 286
LEU A 237
 None
 0.78A 3qeoB-4r9vA:
undetectable		 3qeoB-4r9vA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.03A 3qxyA-4r9vA:
undetectable		 3qxyA-4r9vA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.07A 3rc0A-4r9vA:
undetectable		 3rc0A-4r9vA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 GLY A 230
LEU A 300
TYR A 276
TYR A 286
PHE A 288
 None
 1.06A 3rc0B-4r9vA:
undetectable		 3rc0B-4r9vA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 5 GLY A 363
TRP A 361
ALA A 362
PHE A 495
 None
 1.24A 3wqwA-4r9vA:
undetectable		 3wqwA-4r9vA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 4 LEU A 412
ILE A 378
GLY A 413
PHE A 415
 None
 1.11A 4dc3A-4r9vA:
5.6		 4dc3A-4r9vA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 ASP A 229
THR A 199
TYR A 227
LEU A 123
 None
 1.13A 5b1bA-4r9vA:
undetectable
5b1bC-4r9vA:
undetectable
5b1bP-4r9vA:
undetectable		 5b1bA-4r9vA:
20.53
5b1bC-4r9vA:
21.52
5b1bP-4r9vA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 8 ASP A 229
THR A 199
TYR A 227
LEU A 123
 None
 1.14A 5b3sA-4r9vA:
undetectable
5b3sC-4r9vA:
undetectable
5b3sP-4r9vA:
undetectable		 5b3sA-4r9vA:
20.53
5b3sC-4r9vA:
21.52
5b3sP-4r9vA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 VAL A 178
THR A 197
ILE A 210
GLN A 211
PHE A 195
 None
 1.32A 5hgcA-4r9vA:
undetectable		 5hgcA-4r9vA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 12 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.39A 5iqbD-4r9vA:
undetectable		 5iqbD-4r9vA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 11 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.41A 5iqdD-4r9vA:
0.0		 5iqdD-4r9vA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		6 / 12 VAL A 375
ASN A 379
ILE A 378
ALA A 381
GLY A 413
ILE A 410
 None
 1.45A 5j2tC-4r9vA:
5.6		 5j2tC-4r9vA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 6 ILE A 443
ILE A 382
LEU A 390
PHE A 458
 None
 0.89A 5vkqA-4r9vA:
undetectable
5vkqB-4r9vA:
undetectable		 5vkqA-4r9vA:
12.50
5vkqB-4r9vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		4 / 6 ILE A 443
ILE A 382
LEU A 390
PHE A 458
 None
 0.86A 5vkqA-4r9vA:
undetectable
5vkqD-4r9vA:
undetectable		 5vkqA-4r9vA:
12.50
5vkqD-4r9vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 4r9v SIALYLTRANSFERASE
0160
(Photobacterium
damselae) 		5 / 10 SER A 225
TYR A 196
GLU A 194
SER A 222
TYR A 139
 None
 1.42A 6c5uD-4r9vA:
0.0		 6c5uD-4r9vA:
20.94