SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 GLU A 202
ALA A 204
SER A 239
 None
 0.58A 1errB-4r9zA:
undetectable		 1errB-4r9zA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 6 VAL A   8
SER A 152
LEU A 191
PHE A 156
 None
 1.28A 2f8dA-4r9zA:
undetectable		 2f8dA-4r9zA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 7 ALA A 103
LEU A  44
ALA A  47
PHE A 107
 None
 0.92A 2vcvA-4r9zA:
undetectable		 2vcvA-4r9zA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 SER A  58
SER A 105
HIS A 219
 None
 0.81A 3mzeA-4r9zA:
2.2		 3mzeA-4r9zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 ALA A 103
PHE A  22
ALA A  47
THR A  50
 None
 1.05A 3t3sE-4r9zA:
undetectable		 3t3sE-4r9zA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 LEU A 191
ALA A 189
LEU A  44
LEU A  45
GLY A  37
 None
 1.22A 3uudA-4r9zA:
undetectable		 3uudA-4r9zA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 ARG A  89
GLN A  81
GLU A  82
 None
 0.81A 4tvtA-4r9zA:
undetectable		 4tvtA-4r9zA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 9 ALA A  43
ALA A  41
ALA A 193
ALA A 103
SER A 105
 None
 1.32A 4twdA-4r9zA:
undetectable
4twdB-4r9zA:
undetectable
4twdC-4r9zA:
undetectable
4twdD-4r9zA:
undetectable
4twdE-4r9zA:
undetectable		 4twdA-4r9zA:
20.48
4twdB-4r9zA:
20.48
4twdC-4r9zA:
20.48
4twdD-4r9zA:
20.48
4twdE-4r9zA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 LEU A  12
GLY A  37
LEU A  35
LEU A 191
SER A 152
 None
 1.12A 4wnuA-4r9zA:
undetectable		 4wnuA-4r9zA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 6 ASP A   7
PRO A 177
TYR A 194
LEU A 191
 None
 1.33A 5bmvB-4r9zA:
undetectable		 5bmvB-4r9zA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 SER A  40
GLN A  25
GLN A  26
GLY A  36
GLN A  95
 None
 1.46A 5oj0A-4r9zA:
undetectable		 5oj0A-4r9zA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4r9z UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 TRP A 175
ARG A 159
GLU A 157
GLU A 130
 None
 1.25A 6mn4C-4r9zA:
undetectable		 6mn4C-4r9zA:
20.91