SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ra0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		5 / 10 PHE C 119
SER C 121
LEU C  51
VAL C  53
VAL C 112
 None
 1.50A 3u9fI-4ra0C:
undetectable		 3u9fI-4ra0C:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		5 / 10 PHE C 119
SER C 121
LEU C  51
VAL C  53
VAL C 112
 None
 1.44A 3u9fR-4ra0C:
undetectable		 3u9fR-4ra0C:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		3 / 3 VAL C 112
VAL C  60
GLN C  78
 None
 0.63A 5qgnA-4ra0C:
undetectable		 5qgnA-4ra0C:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		3 / 3 VAL C 112
VAL C  60
GLN C  78
 None
 0.66A 5qh5A-4ra0C:
undetectable		 5qh5A-4ra0C:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		3 / 3 VAL C 112
VAL C  60
GLN C  78
 None
 0.68A 5qh7A-4ra0C:
undetectable		 5qh7A-4ra0C:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4ra0 TYROSINE-PROTEIN
KINASE RECEPTOR UFO
(Homo
sapiens) 		5 / 12 VAL C 216
SER C 152
LEU C 151
VAL C 187
HIS C 186
 None
 1.21A 5ubbA-4ra0C:
undetectable		 5ubbA-4ra0C:
22.17