SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TV8_B_SAMB2501_0 (MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A)	4rb0	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY) (Magnetospirillum gryphiswaldense)	4 / 7	TYR A 80 THR A 17 GLU A 6 VAL A 39	None	1.14A	1tv8B-4rb0A: undetectable	1tv8B-4rb0A: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O0M_A_ACTA146_0 (HIT FAMILY PROTEIN)	4rb0	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY) (Magnetospirillum gryphiswaldense)	4 / 4	ASP A 35 GLU A 37 GLU A 38 ARG A 41	None	1.02A	3o0mA-4rb0A: undetectable	3o0mA-4rb0A: 26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4rb0	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY) (Magnetospirillum gryphiswaldense)	4 / 4	ILE A 5 SER A 3 ASP A 11 ASP A 89	None	1.44A	4krhB-4rb0A: undetectable	4krhB-4rb0A: 18.01

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TV8_B_SAMB2501_0","MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A","4rb0","DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY)","Magnetospirillum gryphiswaldense",4,"TYR A  80;THR A  17;GLU A   6;VAL A  39","None","1.14A","1tv8B-4rb0A:undetectable","1tv8B-4rb0A:18.24"],["3O0M_A_ACTA146_0","HIT FAMILY PROTEIN","4rb0","DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY)","Magnetospirillum gryphiswaldense",4,"ASP A  35;GLU A  37;GLU A  38;ARG A  41","None","1.02A","3o0mA-4rb0A:undetectable","3o0mA-4rb0A:26.16"],["4KRH_B_SAMB900_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4rb0","DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OF SIDEROPHORE BIOSYNTHESIS AND TRANSPORT(FUR FAMILY)","Magnetospirillum gryphiswaldense",4,"ILE A   5;SER A   3;ASP A  11;ASP A  89","None","1.44A","4krhB-4rb0A:undetectable","4krhB-4rb0A:18.01"]]