SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 7 VAL A 497
TYR A 774
LEU A 457
LEU A 456
None
0.75A 1cqpA-4rbnA:
undetectable
1cqpB-4rbnA:
undetectable
1cqpA-4rbnA:
12.66
1cqpB-4rbnA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 5 LEU A  21
GLU A  46
ALA A  17
LEU A  22
None
1.18A 1eta1-4rbnA:
undetectable
1eta1-4rbnA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 5 LEU A  21
GLU A  46
ALA A  17
LEU A  22
None
1.17A 1eta2-4rbnA:
undetectable
1eta2-4rbnA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 6 TRP A 743
HIS A 425
TYR A 293
GLY A 289
None
1.44A 1mxdA-4rbnA:
undetectable
1mxdA-4rbnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
6 / 12 GLY A 405
ASP A 404
ARG A 369
ASN A 401
HIS A 425
ALA A 426
None
1.35A 2bm9F-4rbnA:
2.6
2bm9F-4rbnA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 LEU A 254
LEU A 258
ILE A 261
LEU A 242
ILE A 245
None
1.12A 2f78A-4rbnA:
undetectable
2f78A-4rbnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 LEU A 254
LEU A 258
ILE A 261
LEU A 242
ILE A 245
None
1.06A 2f78B-4rbnA:
undetectable
2f78B-4rbnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 LEU A 254
LEU A 258
ILE A 261
LEU A 242
ILE A 245
None
1.12A 2f7aA-4rbnA:
undetectable
2f7aA-4rbnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 LEU A 254
LEU A 258
ILE A 261
LEU A 242
ILE A 245
None
1.10A 2f8dA-4rbnA:
1.1
2f8dA-4rbnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 LEU A 254
LEU A 258
ILE A 261
LEU A 242
ILE A 245
None
1.10A 2f8dB-4rbnA:
undetectable
2f8dB-4rbnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 8 TYR A 486
ASP A 455
TYR A 483
HIS A 425
None
1.47A 2ha2A-4rbnA:
4.6
2ha2A-4rbnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 8 TYR A 486
ASP A 455
TYR A 483
HIS A 425
None
1.45A 2ha2B-4rbnA:
4.5
2ha2B-4rbnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 9 PHE A 379
ALA A 380
VAL A 383
GLU A 384
None
0.50A 2vufA-4rbnA:
undetectable
2vufA-4rbnA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 ALA A 232
VAL A 235
GLY A 229
GLY A 313
ILE A 213
None
0.90A 2z0yA-4rbnA:
2.1
2z0yA-4rbnA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 LEU A  55
GLN A  12
THR A  11
THR A  45
None
1.41A 2zj0D-4rbnA:
3.3
2zj0D-4rbnA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 8 ILE A 465
ALA A 462
ASN A 406
ALA A 409
None
0.94A 3hrdA-4rbnA:
undetectable
3hrdB-4rbnA:
undetectable
3hrdA-4rbnA:
20.79
3hrdB-4rbnA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 ILE A 245
PRO A 249
SER A 165
SER A 157
LEU A 242
None
1.49A 3ijxB-4rbnA:
0.0
3ijxD-4rbnA:
0.5
3ijxB-4rbnA:
14.61
3ijxD-4rbnA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 7 TYR A 774
GLU A 121
LEU A 775
ASN A 460
None
1.19A 3k8mA-4rbnA:
undetectable
3k8mA-4rbnA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
1.00A 3keeA-4rbnA:
undetectable
3keeA-4rbnA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.91A 3keeB-4rbnA:
undetectable
3keeB-4rbnA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.90A 3keeC-4rbnA:
undetectable
3keeC-4rbnA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.95A 3keeD-4rbnA:
undetectable
3keeD-4rbnA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 ASN A 516
ALA A 517
ALA A 674
SER A 675
ARG A 647
None
1.47A 3kp6B-4rbnA:
undetectable
3kp6B-4rbnA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.17A 3lxiA-4rbnA:
undetectable
3lxiA-4rbnA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 11 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.19A 3lxiB-4rbnA:
undetectable
3lxiB-4rbnA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 TYR A 746
PRO A 513
TYR A 293
VAL A 466
TYR A 741
None
1.41A 3p4wA-4rbnA:
1.6
3p4wA-4rbnA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 VAL A 144
PRO A 513
ILE A 399
CYH A 421
TYR A 293
None
1.44A 3p6gA-4rbnA:
undetectable
3p6gA-4rbnA:
10.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 ALA A 566
ILE A 519
TYR A 520
ILE A 537
THR A 564
None
0.97A 3prsA-4rbnA:
undetectable
3prsA-4rbnA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 6 LEU A 633
VAL A 596
MET A 565
PHE A 563
None
1.03A 3soaA-4rbnA:
undetectable
3soaA-4rbnA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.94A 3sudA-4rbnA:
undetectable
3sudA-4rbnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.89A 3sudC-4rbnA:
undetectable
3sudC-4rbnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.93A 3sudD-4rbnA:
undetectable
3sudD-4rbnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.91A 3sueA-4rbnA:
undetectable
3sueA-4rbnA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.95A 3sueB-4rbnA:
undetectable
3sueB-4rbnA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.95A 3sueC-4rbnA:
undetectable
3sueC-4rbnA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.88A 3sufA-4rbnA:
undetectable
3sufA-4rbnA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.86A 3sufB-4rbnA:
undetectable
3sufB-4rbnA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 11 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.97A 3sufC-4rbnA:
undetectable
3sufC-4rbnA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
None
0.90A 3sufD-4rbnA:
undetectable
3sufD-4rbnA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 ALA A 462
ILE A 398
GLY A 400
ILE A 423
LEU A 753
None
1.19A 3u7sB-4rbnA:
undetectable
3u7sB-4rbnA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 6 ILE A 510
ILE A 269
MET A 750
TRP A 743
None
1.43A 3welA-4rbnA:
2.4
3welA-4rbnA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.16A 4c9kA-4rbnA:
undetectable
4c9kA-4rbnA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.14A 4c9nB-4rbnA:
undetectable
4c9nB-4rbnA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.17A 4c9pA-4rbnA:
undetectable
4c9pA-4rbnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
None
1.21A 4c9pB-4rbnA:
undetectable
4c9pB-4rbnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 ARG A 773
GLU A 770
PHE A 127
None
0.99A 4kszA-4rbnA:
undetectable
4kszA-4rbnA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 ALA A 591
ILE A 655
VAL A 657
ALA A 709
ALA A 713
None
1.09A 4lbgB-4rbnA:
3.1
4lbgB-4rbnA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 ARG A 369
HIS A 273
SER A 368
None
0.88A 4mjwA-4rbnA:
undetectable
4mjwB-4rbnA:
2.6
4mjwA-4rbnA:
22.51
4mjwB-4rbnA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 SER A 368
ARG A 369
HIS A 273
None
0.91A 4mjwA-4rbnA:
undetectable
4mjwB-4rbnA:
2.5
4mjwA-4rbnA:
22.51
4mjwB-4rbnA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 LYS A 107
LYS A 429
ALA A 488
None
0.97A 4ot2A-4rbnA:
1.4
4ot2A-4rbnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 PRO A 226
LEU A 180
GLN A 312
None
0.67A 4pevB-4rbnA:
4.4
4pevB-4rbnA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 MET A 155
LEU A 258
ALA A 259
PHE A 257
LEU A 170
None
0.97A 4psyA-4rbnA:
undetectable
4psyA-4rbnA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 11 PHE A 665
VAL A 737
GLY A 666
SER A 512
GLY A 514
None
1.23A 4xp4A-4rbnA:
undetectable
4xp4A-4rbnA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 ILE A 465
ALA A 424
ALA A 454
ASN A 406
PHE A 508
None
1.50A 4zo1X-4rbnA:
undetectable
4zo1X-4rbnA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 12 ASP A 404
ILE A 294
GLY A 274
PHE A 276
GLY A 289
None
0.98A 5i73A-4rbnA:
undetectable
5i73A-4rbnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 GLU A 536
PRO A 535
ILE A 534
LEU A 533
None
1.16A 5m45A-4rbnA:
undetectable
5m45A-4rbnA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 GLU A 536
PRO A 535
ILE A 534
LEU A 533
None
1.18A 5m45D-4rbnA:
undetectable
5m45D-4rbnA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 GLU A 536
PRO A 535
ILE A 534
LEU A 533
None
1.14A 5m45G-4rbnA:
undetectable
5m45G-4rbnA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 GLU A 536
PRO A 535
ILE A 534
LEU A 533
None
1.21A 5m45J-4rbnA:
undetectable
5m45J-4rbnA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 TYR A 746
PRO A 513
TYR A 293
VAL A 466
TYR A 741
None
1.41A 5mvnC-4rbnA:
1.7
5mvnC-4rbnA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 10 TYR A 746
PRO A 513
TYR A 293
VAL A 466
TYR A 741
None
1.42A 5mvnD-4rbnA:
undetectable
5mvnD-4rbnA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 TYR A 523
SER A 675
TRP A 726
None
1.06A 5n8jB-4rbnA:
undetectable
5n8jB-4rbnA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
3 / 3 TYR A 523
SER A 675
TRP A 726
None
1.03A 5n8jA-4rbnA:
undetectable
5n8jA-4rbnA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN4_A_SC2A1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 4 HIS A 230
GLY A 229
ARG A 234
THR A 238
None
1.49A 5nn4A-4rbnA:
2.3
5nn4A-4rbnA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
5 / 9 LEU A 246
LEU A 196
ILE A 261
LEU A 254
MET A 181
None
1.19A 5og9A-4rbnA:
undetectable
5og9A-4rbnA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 8 GLN A 142
GLU A 689
ILE A 473
GLN A 487
None
1.05A 5vlmD-4rbnA:
undetectable
5vlmD-4rbnA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_C_ACTC608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 5 TYR A 293
GLN A 290
HIS A 425
TYR A 402
None
1.45A 6b58C-4rbnA:
0.7
6b58C-4rbnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea)
4 / 8 GLN A  12
THR A   9
SER A  52
TYR A  25
None
1.11A 6eqpA-4rbnA:
3.7
6eqpA-4rbnA:
6.26