SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 8 LEU A 477
ASP A 468
LEU A 464
LEU A 467
 None
 1.02A 1e7cA-4rd9A:
2.8		 1e7cA-4rd9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 ILE A 456
LEU A 453
VAL A 449
ALA A 442
 None
 0.99A 1mz9A-4rd9A:
1.9		 1mz9A-4rd9A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 9 LEU A 399
PHE A 395
LEU A 473
ARG A 478
LEU A 477
 None
 1.25A 2bxeA-4rd9A:
2.5		 2bxeA-4rd9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 LYS A 314
LEU A 311
ALA A 313
 None
 0.73A 4ikiA-4rd9A:
undetectable		 4ikiA-4rd9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 11 ARG A 414
LEU A 413
SER A 463
LEU A 410
LEU A 464
 None
 1.39A 4or0A-4rd9A:
2.6		 4or0A-4rd9A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 SER A 339
ARG A 347
LEU A 350
ASP A 346
 None
 1.49A 4xdtA-4rd9A:
undetectable		 4xdtA-4rd9A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 MET A 445
GLN A 444
ARG A 446
 None
 0.93A 5ewzB-4rd9A:
6.3		 5ewzB-4rd9A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4rd9 AMYLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 MET A 445
GLN A 444
ARG A 446
 None
 1.06A 5m36A-4rd9A:
7.0		 5m36A-4rd9A:
25.94