SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 4rdj CAPSID
(Norwalk
virus) 		4 / 8 SER A 437
PHE A 439
LEU A 390
LEU A 401
 None
 1.02A 2bfpA-4rdjA:
undetectable		 2bfpA-4rdjA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 4rdj CAPSID
(Norwalk
virus) 		4 / 8 SER A 437
PHE A 439
LEU A 390
LEU A 401
 None
 0.98A 2bfpD-4rdjA:
undetectable		 2bfpD-4rdjA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4rdj CAPSID
(Norwalk
virus) 		3 / 3 CYH A 287
PRO A 322
ASP A 310
 None
 0.99A 3hlwB-4rdjA:
undetectable		 3hlwB-4rdjA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 4rdj CAPSID
(Norwalk
virus) 		4 / 4 ARG A 396
ASP A 374
GLY A 303
THR A 362
 None
 1.09A 3k4vB-4rdjA:
undetectable		 3k4vB-4rdjA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4rdj CAPSID
(Norwalk
virus) 		3 / 3 THR A 336
VAL A 338
GLU A 389
 None
 0.74A 3v4tA-4rdjA:
undetectable
3v4tD-4rdjA:
undetectable		 3v4tA-4rdjA:
20.92
3v4tD-4rdjA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4rdj CAPSID
(Norwalk
virus) 		3 / 3 PRO A 445
VAL A 393
HIS A 334
 None
 0.57A 4pevC-4rdjA:
undetectable		 4pevC-4rdjA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 4rdj CAPSID
(Norwalk
virus) 		3 / 3 CYH A 287
PRO A 322
ASP A 310
 None
 0.91A 4pm5A-4rdjA:
undetectable		 4pm5A-4rdjA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4rdj CAPSID
(Norwalk
virus) 		4 / 6 LEU A 484
ILE A 251
MET A 242
MET A 495
 None
 1.34A 5ljeA-4rdjA:
undetectable		 5ljeA-4rdjA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 4rdj CAPSID
(Norwalk
virus) 		5 / 12 TYR A 409
TYR A 314
GLY A 410
ALA A 416
LEU A 419
 None
 1.23A 5zwrA-4rdjA:
undetectable		 5zwrA-4rdjA:
23.02