SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		3 / 3 GLN A 327
HIS A 326
ARG A 125
 None
 0.90A 4qyqA-4rdqA:
0.0		 4qyqA-4rdqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		3 / 3 GLN A 327
HIS A 326
ARG A 125
 None
 0.84A 4qyqB-4rdqA:
undetectable		 4qyqB-4rdqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		3 / 3 SER A  47
TYR A  43
ASP A 270
 None
 0.71A 4rp8C-4rdqA:
2.8		 4rp8C-4rdqA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		3 / 3 ARG A 125
GLN A 327
GLU A 117
 None
 0.87A 4tvtA-4rdqA:
undetectable		 4tvtA-4rdqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		4 / 5 THR A 348
ALA A 350
THR A 351
TYR A 354
 None
 0.97A 5ecmA-4rdqA:
undetectable		 5ecmA-4rdqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		4 / 6 THR A 348
ALA A 350
THR A 351
TYR A 354
 None
 0.98A 5ecoA-4rdqA:
undetectable		 5ecoA-4rdqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 4rdq BESTROPHIN-1
(Gallus
gallus) 		3 / 3 THR A 307
ALA A 146
ASN A 308
 GOL  A 501 (-4.8A)
GOL  A 501 (-3.2A)
GOL  A 501 (-4.6A)
 0.57A 5ersA-4rdqA:
undetectable		 5ersA-4rdqA:
23.24