SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4reu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 4reu FERRITIN
(Escherichia
coli) 		4 / 5 ASP A 155
GLU A  37
LEU A  43
LEU A 158
 None
 0.96A 1np1A-4reuA:
undetectable		 1np1A-4reuA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4reu FERRITIN
(Escherichia
coli) 		4 / 6 LEU A  23
MET A  27
LEU A  43
GLU A  94
 SO4  A 203 ( 4.9A)
None
None
FE  A 202 (-1.9A)
 1.25A 2kuhA-4reuA:
undetectable		 2kuhA-4reuA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4reu FERRITIN
(Escherichia
coli) 		3 / 3 GLU A  49
HIS A  46
THR A 163
 None
 0.84A 3hkuA-4reuA:
undetectable		 3hkuA-4reuA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 4reu FERRITIN
(Escherichia
coli) 		4 / 4 HIS A 128
GLU A  94
HIS A  46
LEU A 161
 None
FE  A 202 (-1.9A)
None
None
 1.40A 4m2rA-4reuA:
undetectable		 4m2rA-4reuA:
17.69