SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rfa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4rfa LMO0740 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ILE A  90
ILE A 174
ILE A  67
LEU A  29
 None
 0.92A 1zgyA-4rfaA:
undetectable		 1zgyA-4rfaA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 4rfa LMO0740 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A 157
ILE A  67
PHE A  68
VAL A  53
 None
 1.44A 4tvtA-4rfaA:
undetectable		 4tvtA-4rfaA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 4rfa LMO0740 PROTEIN
(Listeria
monocytogenes) 		5 / 12 VAL A  53
ILE A  90
ILE A  46
PHE A  35
ILE A 125
 None
 1.11A 5hw8B-4rfaA:
undetectable
5hw8F-4rfaA:
undetectable
5hw8G-4rfaA:
undetectable		 5hw8B-4rfaA:
17.62
5hw8F-4rfaA:
17.62
5hw8G-4rfaA:
17.62