SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.43A 1th6A-4rfpA:
20.1		 1th6A-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		5 / 11 LEU A   2
GLY A  32
HIS A  47
TYR A  51
LYS A  60
 None
 1.31A 1y4lB-4rfpA:
20.7		 1y4lB-4rfpA:
49.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.45A 2armA-4rfpA:
20.1		 2armA-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		5 / 10 ILE A  18
GLY A  29
HIS A  47
ASP A  48
PHE A  96
 None
 1.05A 2b17A-4rfpA:
20.0		 2b17A-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		5 / 10 LEU A   2
ILE A  18
GLY A  29
ASP A  48
PHE A  96
 None
 1.15A 2b17A-4rfpA:
20.0		 2b17A-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 6 LEU A   2
HIS A  47
ASP A  48
TYR A  51
 None
 0.72A 2dpzA-4rfpA:
20.3		 2dpzA-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 5 ILE A  18
SER A  22
GLY A  29
HIS A  47
 None
 0.87A 2otfA-4rfpA:
20.2		 2otfA-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 5 LEU A   2
ILE A  18
SER A  22
GLY A  29
 None
 0.64A 2otfA-4rfpA:
20.2		 2otfA-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		5 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.86A 3fo7A-4rfpA:
20.0		 3fo7A-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.45A 3h1xA-4rfpA:
20.1		 3h1xA-4rfpA:
53.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		3 / 3 ARG A  97
ASP A 101
ASP A  98
 None
 0.87A 3jb2A-4rfpA:
undetectable		 3jb2A-4rfpA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		3 / 3 ARG A  97
ASP A 101
ASP A  98
 None
 0.75A 3jb3A-4rfpA:
undetectable		 3jb3A-4rfpA:
7.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		6 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  29
LYS A  30
HIS A  47
 None
 0.75A 3oshA-4rfpA:
18.0		 3oshA-4rfpA:
41.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 4rfp ACIDIC PHOSPHOLIPASE
A2 5
(Trimeresurus
stejnegeri) 		5 / 9 VAL A  46
ALA A  92
PHE A  96
TYR A 103
TYR A  24
 None
None
None
PEG  A 201 ( 4.1A)
None
 1.47A 4lb2B-4rfpA:
undetectable		 4lb2B-4rfpA:
12.55