SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.18A 1p7lC-4rftA:
undetectable
1p7lC-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.17A 1p7lD-4rftA:
undetectable
1p7lD-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.16A 1rg9A-4rftA:
undetectable
1rg9A-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.18A 1rg9B-4rftA:
undetectable
1rg9B-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.19A 1rg9C-4rftA:
undetectable
1rg9C-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.17A 1rg9D-4rftA:
undetectable
1rg9D-4rftA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 TRP A 152
THR A  72
TYR A  77
None
1.18A 2a3aA-4rftA:
undetectable
2a3aA-4rftA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 TRP A 152
THR A  72
TYR A  77
None
1.18A 2a3aB-4rftA:
undetectable
2a3aB-4rftA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 TRP A 152
THR A  72
TYR A  77
None
1.18A 2a3bA-4rftA:
undetectable
2a3bA-4rftA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 LEU A  89
PRO A  90
ARG A 202
None
0.59A 2qd4B-4rftA:
undetectable
2qd4B-4rftA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 LEU A  89
PRO A  90
ARG A 202
None
0.41A 2qd5A-4rftA:
undetectable
2qd5A-4rftA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
5 / 12 SER A  61
ILE A 111
ASP A  81
ARG A 182
LEU A 183
None
1.24A 3iv6D-4rftA:
undetectable
3iv6D-4rftA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 ASP A 130
ARG A 176
ARG A 145
None
0.99A 3k37A-4rftA:
undetectable
3k37A-4rftA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 7 ILE A  84
VAL A  85
TYR A 102
GLN A 175
None
1.31A 5kkzM-4rftA:
undetectable
5kkzO-4rftA:
undetectable
5kkzM-4rftA:
20.51
5kkzO-4rftA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 THR A 169
PRO A  86
ASP A  87
None
0.94A 5l8dB-4rftA:
undetectable
5l8dB-4rftA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
3 / 3 THR A 169
PRO A  86
ASP A  87
None
0.94A 5mwuB-4rftA:
undetectable
5mwuB-4rftA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
4 / 8 SER A 211
THR A 169
PHE A  99
ASP A  54
None
1.18A 5t8sB-4rftA:
undetectable
5t8sB-4rftA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)
4rft COAT PROTEIN
(Redspotted
grouper
nervous
necrosis
virus)
5 / 12 ALA A  82
ASP A  81
VAL A 199
GLY A 126
ILE A  63
None
0.78A 6dj1A-4rftA:
undetectable
6dj1A-4rftA:
19.21