SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_A_BEZA352_0 (D-AMINO-ACID OXIDASE)	4rgi	UNCHARACTERIZED PROTEIN (Yersinia pestis)	4 / 6	LEU A 23 TYR A 35 ILE A 25 GLY A 58	None	0.81A	2du8A-4rgiA: undetectable	2du8A-4rgiA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_B_BEZB1352_0 (D-AMINO-ACID OXIDASE)	4rgi	UNCHARACTERIZED PROTEIN (Yersinia pestis)	4 / 6	LEU A 23 TYR A 35 ILE A 25 GLY A 58	None	0.84A	2du8B-4rgiA: undetectable	2du8B-4rgiA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_O_TFPO201_1 (PROTEIN S100-A4)	4rgi	UNCHARACTERIZED PROTEIN (Yersinia pestis)	4 / 8	GLY A 70 PHE A 56 GLY A 31 PHE A 27	None	0.87A	3ko0O-4rgiA: undetectable 3ko0Q-4rgiA: undetectable	3ko0O-4rgiA: 20.59 3ko0Q-4rgiA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA503_1 (CYTOCHROME P450 2C9)	4rgi	UNCHARACTERIZED PROTEIN (Yersinia pestis)	5 / 12	ILE A 60 GLN A 44 ASN A 45 PRO A 18 PRO A 39	None None None None GOL A 104 (-4.6A)	1.27A	5xxiA-4rgiA: undetectable	5xxiA-4rgiA: 11.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DU8_A_BEZA352_0","D-AMINO-ACID OXIDASE","4rgi","UNCHARACTERIZED PROTEIN","Yersinia pestis",4,"LEU A  23;TYR A  35;ILE A  25;GLY A  58","None","0.81A","2du8A-4rgiA:undetectable","2du8A-4rgiA:12.39"],["2DU8_B_BEZB1352_0","D-AMINO-ACID OXIDASE","4rgi","UNCHARACTERIZED PROTEIN","Yersinia pestis",4,"LEU A  23;TYR A  35;ILE A  25;GLY A  58","None","0.84A","2du8B-4rgiA:undetectable","2du8B-4rgiA:12.39"],["3KO0_O_TFPO201_1","PROTEIN S100-A4;PROTEIN S100-A4","4rgi","UNCHARACTERIZED PROTEIN","Yersinia pestis",4,"GLY A  70;PHE A  56;GLY A  31;PHE A  27","None","0.87A","3ko0O-4rgiA:undetectable;3ko0Q-4rgiA:undetectable","3ko0O-4rgiA:20.59;3ko0Q-4rgiA:20.59"],["5XXI_A_LSNA503_1","CYTOCHROME P450 2C9","4rgi","UNCHARACTERIZED PROTEIN","Yersinia pestis",5,"ILE A  60;GLN A  44;ASN A  45;PRO A  18;PRO A  39","None;None;None;None;GOL A 104 (-4.6A)","1.27A","5xxiA-4rgiA:undetectable","5xxiA-4rgiA:11.44"]]