SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4rgn 14G8 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 124
PRO B 154
THR B 123
PRO B 125
 None
 1.33A 1dsdC-4rgnB:
undetectable		 1dsdC-4rgnB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4rgn 14G8 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR B 124
PRO B 154
THR B 123
PRO B 125
 None
 1.33A 1dsdC-4rgnB:
undetectable		 1dsdC-4rgnB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4rgn 14G8 HEAVY CHAIN
(Mus
musculus) 		4 / 6 VAL B  96
TYR B  93
VAL B  37
TRP B 110
 None
 0.97A 5jwaH-4rgnB:
undetectable		 5jwaH-4rgnB:
17.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 4rgn 14G8 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR B  59
GLY B  65
THR B  68
 None
 0.12A 6cjkB-4rgnB:
25.2		 6cjkB-4rgnB:
56.00