SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 4rhp UBIQUINONE
BIOSYNTHESIS PROTEIN
COQ9, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 LEU A 145
ALA A 135
GLY A 124
ALA A 125
LEU A  99
 None
 1.01A 1nr6A-4rhpA:
undetectable		 1nr6A-4rhpA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4rhp UBIQUINONE
BIOSYNTHESIS PROTEIN
COQ9, MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 LEU A 147
VAL A 160
LEU A 161
ARG A 191
 None
 1.12A 2oiqA-4rhpA:
undetectable		 2oiqA-4rhpA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 4rhp UBIQUINONE
BIOSYNTHESIS PROTEIN
COQ9, MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 LEU A 193
LEU A 204
THR A 254
ARG A 244
 None
None
None
PEF  A 401 (-3.9A)
 1.11A 6ew0F-4rhpA:
undetectable		 6ew0F-4rhpA:
16.02