SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ri1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_B_TFPB203_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4ri1	UDP-4-AMINO-4,6-DIDE OXY-N-ACETYL-BETA-L- ALTROSAMINE N-ACETYLTRANSFERASE (Helicobacter pylori)	4 / 6	PHE A 15 VAL A 26 PHE A 52 SER A 41	None None ACT A1302 (-2.7A) None	1.03A	1wrlB-4ri1A: undetectable	1wrlB-4ri1A: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I30_A_SALA1100_1 (SERUM ALBUMIN)	4ri1	UDP-4-AMINO-4,6-DIDE OXY-N-ACETYL-BETA-L- ALTROSAMINE N-ACETYLTRANSFERASE (Helicobacter pylori)	4 / 6	PHE A 115 TYR A 166 GLY A 171 LYS A 170	None	1.34A	2i30A-4ri1A: undetectable	2i30A-4ri1A: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BPH_C_ACTC403_0 (D-ALANINE--D-ALANINE LIGASE)	4ri1	UDP-4-AMINO-4,6-DIDE OXY-N-ACETYL-BETA-L- ALTROSAMINE N-ACETYLTRANSFERASE (Helicobacter pylori)	4 / 4	TYR A 138 GLY A 77 SER A 78 LEU A 91	ACO A1301 (-4.5A) None None None	1.33A	5bphC-4ri1A: undetectable	5bphC-4ri1A: 24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KI6_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	4ri1	UDP-4-AMINO-4,6-DIDE OXY-N-ACETYL-BETA-L- ALTROSAMINE N-ACETYLTRANSFERASE (Helicobacter pylori)	4 / 5	LEU A 91 TYR A 90 LEU A 123 TYR A 143	None	1.44A	5ki6A-4ri1A: undetectable	5ki6A-4ri1A: 12.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_B_TFPB203_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","4ri1","UDP-4-AMINO-4,6-DIDEOXY-N-ACETYL-BETA-L-ALTROSAMINE N-ACETYLTRANSFERASE","Helicobacter pylori",4,"PHE A  15;VAL A  26;PHE A  52;SER A  41","None;None;ACT A1302 (-2.7A);None","1.03A","1wrlB-4ri1A:undetectable","1wrlB-4ri1A:19.78"],["2I30_A_SALA1100_1","SERUM ALBUMIN","4ri1","UDP-4-AMINO-4,6-DIDEOXY-N-ACETYL-BETA-L-ALTROSAMINE N-ACETYLTRANSFERASE","Helicobacter pylori",4,"PHE A 115;TYR A 166;GLY A 171;LYS A 170","None","1.34A","2i30A-4ri1A:undetectable","2i30A-4ri1A:13.97"],["5BPH_C_ACTC403_0","D-ALANINE--D-ALANINE LIGASE","4ri1","UDP-4-AMINO-4,6-DIDEOXY-N-ACETYL-BETA-L-ALTROSAMINE N-ACETYLTRANSFERASE","Helicobacter pylori",4,"TYR A 138;GLY A  77;SER A  78;LEU A  91","ACO A1301 (-4.5A);None;None;None","1.33A","5bphC-4ri1A:undetectable","5bphC-4ri1A:24.28"],["5KI6_A_IPHA901_0","PROTEIN ARGONAUTE-2","4ri1","UDP-4-AMINO-4,6-DIDEOXY-N-ACETYL-BETA-L-ALTROSAMINE N-ACETYLTRANSFERASE","Helicobacter pylori",4,"LEU A  91;TYR A  90;LEU A 123;TYR A 143","None","1.44A","5ki6A-4ri1A:undetectable","5ki6A-4ri1A:12.59"]]