SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ri2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 GLN A 169
GLU A 159
THR A 162
PHE A 152
PHE A 154
 None
 1.25A 3ag4A-4ri2A:
1.4
3ag4B-4ri2A:
undetectable
3ag4T-4ri2A:
undetectable		 3ag4A-4ri2A:
18.06
3ag4B-4ri2A:
21.95
3ag4T-4ri2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 11 ALA A 195
GLY A  41
GLY A 145
ILE A 197
VAL A  43
 None
None
None
None
BNG  A 302 (-4.2A)
 0.97A 3dcmX-4ri2A:
undetectable		 3dcmX-4ri2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 LEU A 156
PHE A  84
GLY A  47
SER A  51
LEU A  52
 None
BNG  A 301 (-4.9A)
None
None
None
 1.03A 3n8xA-4ri2A:
undetectable		 3n8xA-4ri2A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 LEU A 156
PHE A  84
GLY A  47
SER A  51
LEU A  52
 None
BNG  A 301 (-4.9A)
None
None
None
 1.08A 3n8xB-4ri2A:
undetectable		 3n8xB-4ri2A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 ASP A 207
ASP A  21
GLY A  22
ARG A 146
 None
 0.95A 3s3mA-4ri2A:
undetectable		 3s3mA-4ri2A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 PHE A 191
VAL A 144
GLU A 141
 None
 0.84A 4fvqA-4ri2A:
undetectable		 4fvqA-4ri2A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 GLY A  97
ASP A  98
GLU A  35
VAL A 103
 None
None
BNG  A 301 ( 4.4A)
None
 1.15A 4nkvD-4ri2A:
undetectable		 4nkvD-4ri2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4ri2 PHOTOSYSTEM II 22
KDA PROTEIN,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 THR A 174
ILE A 178
GLU A 182
VAL A 189
LEU A  52
 None
 1.40A 4r3aB-4ri2A:
undetectable		 4r3aB-4ri2A:
21.29