SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rjk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 VAL A  81
LEU A  96
GLY A 111
ALA A 110
SER A 170
 None
 0.99A 1eqhA-4rjkA:
undetectable		 1eqhA-4rjkA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 VAL A  81
LEU A  96
GLY A 111
ALA A 110
SER A 170
 None
 0.95A 1eqhB-4rjkA:
undetectable		 1eqhB-4rjkA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 10 VAL A 388
ARG A 385
VAL A 545
VAL A 448
LEU A 384
 None
 1.12A 1fe2A-4rjkA:
undetectable		 1fe2A-4rjkA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 8 PHE A 171
ILE A 148
LEU A 109
VAL A 152
 None
 0.91A 1fslB-4rjkA:
undetectable		 1fslB-4rjkA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.73A 1ictD-4rjkA:
undetectable		 1ictD-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.25A 1kifA-4rjkA:
undetectable		 1kifA-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.26A 1kifB-4rjkA:
undetectable		 1kifB-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.26A 1kifC-4rjkA:
undetectable		 1kifC-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.26A 1kifD-4rjkA:
undetectable		 1kifD-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.26A 1kifE-4rjkA:
undetectable		 1kifE-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.26A 1kifF-4rjkA:
undetectable		 1kifF-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.25A 1kifG-4rjkA:
undetectable		 1kifG-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.25A 1kifH-4rjkA:
undetectable		 1kifH-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.58A 1sn5C-4rjkA:
undetectable		 1sn5C-4rjkA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.63A 1tyrB-4rjkA:
undetectable		 1tyrB-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 ALA A 196
GLY A 194
ALA A 200
ILE A 329
HIS A 335
 None
 1.10A 1ve3A-4rjkA:
undetectable		 1ve3A-4rjkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 ALA A 196
GLY A 194
ALA A 200
ILE A 329
HIS A 335
 None
 1.14A 1ve3B-4rjkA:
2.2		 1ve3B-4rjkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.32A 1ve9A-4rjkA:
undetectable		 1ve9A-4rjkA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 TYR A 287
TYR A 319
ILE A 305
GLY A 219
 None
 1.30A 2du8J-4rjkA:
undetectable		 2du8J-4rjkA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 213
PHE A 345
LEU A 353
PHE A 261
 None
 1.05A 2eimP-4rjkA:
undetectable
2eimW-4rjkA:
undetectable		 2eimP-4rjkA:
18.58
2eimW-4rjkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 ILE A  36
GLY A  35
GLY A  88
ILE A  56
ALA A  64
 None
 0.99A 2fk8A-4rjkA:
undetectable		 2fk8A-4rjkA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		3 / 3 ASN A 386
ILE A 380
MET A 405
 None
 0.77A 2h42C-4rjkA:
undetectable		 2h42C-4rjkA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 GLY A 103
GLY A  79
GLY A 165
HIS A  32
VAL A  71
 None
 0.82A 2oxtD-4rjkA:
undetectable		 2oxtD-4rjkA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 8 PRO A  78
SER A 160
VAL A  30
GLY A  29
 None
PG4  A 603 ( 4.9A)
None
None
 0.82A 2qd3A-4rjkA:
undetectable		 2qd3A-4rjkA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		3 / 3 VAL A 145
ASP A 144
GLU A 178
 None
 0.59A 2qeuA-4rjkA:
undetectable		 2qeuA-4rjkA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		3 / 3 VAL A 145
ASP A 144
GLU A 178
 None
 0.60A 2qeuC-4rjkA:
undetectable		 2qeuC-4rjkA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  98
LEU A  97
TYR A 481
PHE A  66
VAL A 428
 None
None
TPP  A 601 (-4.2A)
None
None
 1.20A 2vaxB-4rjkA:
0.0		 2vaxB-4rjkA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  98
LEU A  97
TYR A 481
PHE A  66
VAL A 428
 None
None
TPP  A 601 (-4.2A)
None
None
 1.24A 2vaxD-4rjkA:
0.2		 2vaxD-4rjkA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  98
LEU A  97
TYR A 481
PHE A  66
VAL A 428
 None
None
TPP  A 601 (-4.2A)
None
None
 1.21A 2vaxH-4rjkA:
0.2		 2vaxH-4rjkA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  98
LEU A  97
TYR A 481
PHE A  66
VAL A 428
 None
None
TPP  A 601 (-4.2A)
None
None
 1.19A 2vaxI-4rjkA:
0.2		 2vaxI-4rjkA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  98
LEU A  97
TYR A 481
PHE A  66
VAL A 428
 None
None
TPP  A 601 (-4.2A)
None
None
 1.21A 2vaxK-4rjkA:
undetectable		 2vaxK-4rjkA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 213
PHE A 345
LEU A 353
PHE A 261
 None
 1.03A 3asnP-4rjkA:
undetectable
3asnW-4rjkA:
undetectable		 3asnP-4rjkA:
18.58
3asnW-4rjkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 213
PHE A 345
LEU A 353
PHE A 261
 None
 1.04A 3asoP-4rjkA:
undetectable
3asoW-4rjkA:
undetectable		 3asoP-4rjkA:
18.58
3asoW-4rjkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 6 VAL A  71
LEU A 417
MET A 418
ILE A  56
 None
 0.80A 3gcsA-4rjkA:
undetectable		 3gcsA-4rjkA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 VAL A  21
VAL A  80
LEU A 109
GLY A  29
LEU A  25
 None
 1.17A 3pghA-4rjkA:
undetectable		 3pghA-4rjkA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 10 VAL A 445
GLY A 435
ALA A 436
ALA A  70
THR A 395
 None
 1.01A 3ucjA-4rjkA:
undetectable		 3ucjA-4rjkA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 10 VAL A 445
GLY A 435
ALA A 436
ALA A  70
THR A 395
 None
 1.01A 3ucjB-4rjkA:
undetectable		 3ucjB-4rjkA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 PHE A 168
LEU A 126
GLY A  86
VAL A  83
 None
 1.08A 3wrkD-4rjkA:
undetectable		 3wrkD-4rjkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A 356
GLN A 358
PHE A 261
LEU A 275
 None
 0.97A 3x2qP-4rjkA:
undetectable
3x2qW-4rjkA:
undetectable		 3x2qP-4rjkA:
18.58
3x2qW-4rjkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 MET A 483
ASN A 269
ASP A 273
GLY A 265
GLN A 424
 TPP  A 601 (-4.0A)
None
None
None
None
 1.38A 4djeB-4rjkA:
undetectable		 4djeB-4rjkA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.60A 4ik7B-4rjkA:
undetectable		 4ik7B-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		3 / 3 GLY A 222
GLU A 244
THR A 245
 None
 0.59A 4kouA-4rjkA:
undetectable		 4kouA-4rjkA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 VAL A 152
LEU A  25
VAL A  30
PHE A 156
 None
 1.00A 4lb0B-4rjkA:
undetectable		 4lb0B-4rjkA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 10 VAL A  81
LEU A  96
GLY A 111
ALA A 110
SER A 170
 None
 1.05A 4ph9A-4rjkA:
undetectable		 4ph9A-4rjkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 10 VAL A  81
LEU A  96
GLY A 111
ALA A 110
SER A 170
 None
 1.05A 4ph9B-4rjkA:
undetectable		 4ph9B-4rjkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 GLY A  86
GLY A  88
GLY A 111
ALA A 110
ILE A 114
 None
 1.00A 4rtmA-4rjkA:
undetectable		 4rtmA-4rjkA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 GLY A 265
ARG A 407
SER A 420
GLU A 102
TYR A 287
 None
 1.03A 5czyA-4rjkA:
undetectable		 5czyA-4rjkA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 ALA A 346
PRO A 214
GLY A 219
LEU A 235
 None
 1.02A 5eslA-4rjkA:
undetectable		 5eslA-4rjkA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 6 VAL A 152
VAL A  30
ILE A  56
PHE A  34
 None
 0.87A 5jw1B-4rjkA:
undetectable		 5jw1B-4rjkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 GLN A 247
GLY A 422
ILE A 398
GLN A 487
 None
 1.00A 5vlmC-4rjkA:
undetectable		 5vlmC-4rjkA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 8 GLN A 247
GLY A 422
ILE A 398
GLN A 487
 None
 0.93A 5vlmD-4rjkA:
undetectable		 5vlmD-4rjkA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 LEU A 213
PHE A 345
LEU A 353
PHE A 261
 None
 1.04A 5x19C-4rjkA:
undetectable
5x19J-4rjkA:
undetectable		 5x19C-4rjkA:
18.58
5x19J-4rjkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 5 PRO A  37
GLY A  38
THR A  84
LYS A  40
 None
 1.19A 5x23A-4rjkA:
undetectable		 5x23A-4rjkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 6 PHE A 132
PRO A 134
THR A 136
LYS A 137
 None
 0.99A 5x24A-4rjkA:
undetectable		 5x24A-4rjkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 LEU A 126
GLY A  86
VAL A  44
ILE A  41
ASP A  42
 None
 1.30A 6bxnB-4rjkA:
undetectable		 6bxnB-4rjkA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 9 VAL A 428
GLY A 427
ILE A 135
LEU A  96
ASP A 104
 None
 1.47A 6c2mC-4rjkA:
undetectable		 6c2mC-4rjkA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 LEU A  96
PHE A 156
VAL A 152
VAL A  30
ALA A  64
 None
 1.03A 6djzA-4rjkA:
undetectable		 6djzA-4rjkA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4rjk ACETOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 LEU A  96
PHE A 156
VAL A 152
VAL A  30
ALA A  64
 None
 1.10A 6djzC-4rjkA:
undetectable		 6djzC-4rjkA:
17.64