SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WU8_C_ADNC502_1 (HYPOTHETICAL PROTEIN PH0463)	4rl9	CARBAPENEM-ASSOCIATE D RESISTANCE PROTEIN (Acinetobacter baumannii)	4 / 7	ASN A 78 ASN A 49 ARG A 22 VAL A 219	None	1.29A	1wu8A-4rl9A: undetectable 1wu8C-4rl9A: undetectable	1wu8A-4rl9A: 19.20 1wu8C-4rl9A: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROD_D_NCAD302_0 (NICOTINAMIDE N-METHYLTRANSFERASE)	4rl9	CARBAPENEM-ASSOCIATE D RESISTANCE PROTEIN (Acinetobacter baumannii)	4 / 7	TYR A 48 ASP A 71 ASP A 52 TYR A 30	None	1.14A	3rodD-4rl9A: undetectable	3rodD-4rl9A: 20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	4rl9	CARBAPENEM-ASSOCIATE D RESISTANCE PROTEIN (Acinetobacter baumannii)	4 / 7	TYR A 173 LEU A 104 ASN A 72 TYR A 48	None	1.34A	4f8yC-4rl9A: undetectable 4f8yD-4rl9A: undetectable	4f8yC-4rl9A: 23.08 4f8yD-4rl9A: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_H_377H401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	4rl9	CARBAPENEM-ASSOCIATE D RESISTANCE PROTEIN (Acinetobacter baumannii)	4 / 6	ASN A 74 GLU A 24 GLU A 169 TYR A 151	None	1.46A	4twdG-4rl9A: undetectable 4twdH-4rl9A: undetectable	4twdG-4rl9A: 22.05 4twdH-4rl9A: 22.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WU8_C_ADNC502_1","HYPOTHETICAL PROTEIN PH0463;HYPOTHETICAL PROTEIN PH0463","4rl9","CARBAPENEM-ASSOCIATED RESISTANCE PROTEIN","Acinetobacter baumannii",4,"ASN A  78;ASN A  49;ARG A  22;VAL A 219","None","1.29A","1wu8A-4rl9A:undetectable;1wu8C-4rl9A:undetectable","1wu8A-4rl9A:19.20;1wu8C-4rl9A:19.20"],["3ROD_D_NCAD302_0","NICOTINAMIDE N-METHYLTRANSFERASE","4rl9","CARBAPENEM-ASSOCIATED RESISTANCE PROTEIN","Acinetobacter baumannii",4,"TYR A  48;ASP A  71;ASP A  52;TYR A  30","None","1.14A","3rodD-4rl9A:undetectable","3rodD-4rl9A:20.46"],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","4rl9","CARBAPENEM-ASSOCIATED RESISTANCE PROTEIN","Acinetobacter baumannii",4,"TYR A 173;LEU A 104;ASN A  72;TYR A  48","None","1.34A","4f8yC-4rl9A:undetectable;4f8yD-4rl9A:undetectable","4f8yC-4rl9A:23.08;4f8yD-4rl9A:23.08"],["4TWD_H_377H401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","4rl9","CARBAPENEM-ASSOCIATED RESISTANCE PROTEIN","Acinetobacter baumannii",4,"ASN A  74;GLU A  24;GLU A 169;TYR A 151","None","1.46A","4twdG-4rl9A:undetectable;4twdH-4rl9A:undetectable","4twdG-4rl9A:22.05;4twdH-4rl9A:22.05"]]