SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4rlc OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 7 SER A   5
PHE A  36
ASN A 159
HIS A  76
 None
 1.08A 4ws0A-4rlcA:
undetectable		 4ws0A-4rlcA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 4rlc OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		5 / 10 ASP A 134
ALA A  10
PHE A  11
SER A 132
GLY A 155
 None
C8E  A 202 ( 4.1A)
None
None
None
 1.21A 4xp1A-4rlcA:
undetectable		 4xp1A-4rlcA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4rlc OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  34
GLU A   9
ILE A  74
ASP A  72
 C8E  A 207 ( 4.3A)
None
None
None
 1.05A 5vlmD-4rlcA:
undetectable		 5vlmD-4rlcA:
22.44