SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2270
SER A2274
VAL A2314
LEU A2317
ALA A2323
 None
 1.10A 1fo4A-4rlvA:
undetectable		 1fo4A-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2336
THR A2381
VAL A2380
LEU A2383
ALA A2389
 None
 1.36A 1fo4A-4rlvA:
undetectable		 1fo4A-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 ALA A2455
HIS A2436
LEU A2444
ALA A2439
LEU A2483
 None
None
SO4  A2906 (-4.3A)
None
None
 1.31A 1mjlA-4rlvA:
undetectable
1mjlB-4rlvA:
undetectable		 1mjlA-4rlvA:
8.96
1mjlB-4rlvA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 4 THR A2381
LEU A2384
VAL A2348
LEU A2351
 None
 0.95A 1mz9D-4rlvA:
undetectable		 1mz9D-4rlvA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG A2539
TYR A2573
LYS A2572
 None
 1.02A 1uujB-4rlvA:
undetectable		 1uujB-4rlvA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 8 SER A2646
ALA A2636
ALA A2669
LEU A2666
 None
 0.72A 2bxmA-4rlvA:
undetectable		 2bxmA-4rlvA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 PRO A2269
LEU A2285
ARG A2288
 None
 0.61A 3aqiB-4rlvA:
undetectable		 3aqiB-4rlvA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 PRO A2302
LEU A2318
ARG A2321
 None
 0.54A 3aqiB-4rlvA:
undetectable		 3aqiB-4rlvA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 8 ALA A2294
THR A2262
ILE A2267
THR A2268
 None
 0.93A 3bpxA-4rlvA:
undetectable
3bpxB-4rlvA:
undetectable		 3bpxA-4rlvA:
9.47
3bpxB-4rlvA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 8 HIS A2773
GLY A2739
ASN A2740
TYR A2738
 None
 1.29A 3ccfA-4rlvA:
undetectable		 3ccfA-4rlvA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 4 LEU A2567
PRO A2566
LEU A2582
ARG A2586
 None
 1.49A 3hcoA-4rlvA:
undetectable		 3hcoA-4rlvA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 12 GLY A2685
ALA A2686
ILE A2688
ILE A2657
LEU A2681
 None
 1.06A 3ogqB-4rlvA:
undetectable		 3ogqB-4rlvA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 5 LEU A2336
SER A2334
ARG A2328
LEU A2351
 None
 1.36A 3onnA-4rlvA:
undetectable		 3onnA-4rlvA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 12 ALA A2588
ALA A2587
LEU A2576
THR A2565
LEU A2567
 None
 1.06A 3p2kA-4rlvA:
undetectable		 3p2kA-4rlvA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 12 ASN A2066
ILE A2057
LEU A2051
ALA A2071
VAL A2047
 None
 1.00A 3rukA-4rlvA:
undetectable		 3rukA-4rlvA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2270
SER A2274
VAL A2314
LEU A2317
ALA A2323
 None
 1.13A 3unaA-4rlvA:
undetectable		 3unaA-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2270
SER A2274
VAL A2314
LEU A2317
ALA A2323
 None
 1.09A 3unaB-4rlvA:
undetectable		 3unaB-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2270
SER A2274
VAL A2314
LEU A2317
ALA A2323
 None
 1.12A 3uncA-4rlvA:
undetectable		 3uncA-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2336
THR A2381
VAL A2380
LEU A2383
ALA A2389
 None
 1.37A 3uncA-4rlvA:
undetectable		 3uncA-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2270
SER A2274
VAL A2314
LEU A2317
ALA A2323
 None
 1.11A 3uncB-4rlvA:
undetectable		 3uncB-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A2336
THR A2381
VAL A2380
LEU A2383
ALA A2389
 None
 1.37A 3uncB-4rlvA:
undetectable		 3uncB-4rlvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 LEU A2385
LYS A2382
THR A2381
 None
 0.57A 4lj0A-4rlvA:
undetectable		 4lj0A-4rlvA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 CYH A2375
ALA A2368
LEU A2384
VAL A2413
LEU A2417
 None
 1.16A 4p65C-4rlvA:
undetectable
4p65D-4rlvA:
undetectable
4p65J-4rlvA:
undetectable
4p65L-4rlvA:
undetectable		 4p65C-4rlvA:
5.32
4p65D-4rlvA:
4.73
4p65J-4rlvA:
4.73
4p65L-4rlvA:
4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 LEU A2171
ALA A2195
LEU A2211
VAL A2248
LEU A2252
 None
 1.14A 4p65C-4rlvA:
undetectable
4p65D-4rlvA:
undetectable
4p65J-4rlvA:
undetectable
4p65L-4rlvA:
undetectable		 4p65C-4rlvA:
5.32
4p65D-4rlvA:
4.73
4p65J-4rlvA:
4.73
4p65L-4rlvA:
4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 7 THR A2659
ALA A2626
THR A2625
ALA A2624
 None
 0.90A 4qw0K-4rlvA:
undetectable		 4qw0K-4rlvA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 7 THR A2659
ALA A2626
THR A2625
ALA A2624
 None
 0.90A 4qw0Y-4rlvA:
undetectable		 4qw0Y-4rlvA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 4 ILE A2427
ASN A2461
ILE A1588
VAL A2437
 None
 1.21A 4uy87-4rlvA:
undetectable		 4uy87-4rlvA:
2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 LEU A2251
LEU A2252
LEU A2212
ALA A2195
LEU A2196
 None
 0.98A 4wg0H-4rlvA:
undetectable
4wg0I-4rlvA:
undetectable
4wg0J-4rlvA:
undetectable		 4wg0H-4rlvA:
1.21
4wg0I-4rlvA:
1.21
4wg0J-4rlvA:
1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 LEU A2251
LEU A2252
LEU A2212
ALA A2195
LEU A2196
 None
 0.96A 4wg0J-4rlvA:
undetectable
4wg0K-4rlvA:
undetectable
4wg0L-4rlvA:
undetectable		 4wg0J-4rlvA:
1.21
4wg0K-4rlvA:
1.21
4wg0L-4rlvA:
1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 ALA A2195
LEU A2196
LEU A2212
LEU A2251
LEU A2252
 None
 0.95A 4wg0I-4rlvA:
undetectable
4wg0J-4rlvA:
undetectable
4wg0K-4rlvA:
undetectable		 4wg0I-4rlvA:
1.21
4wg0J-4rlvA:
1.21
4wg0K-4rlvA:
1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 5 SER A2274
ALA A2273
MET A1607
LEU A2270
 None
 0.97A 5dzkb-4rlvA:
undetectable
5dzkp-4rlvA:
undetectable		 5dzkb-4rlvA:
13.96
5dzkp-4rlvA:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 5 SER A2274
ALA A2273
MET A1607
LEU A2270
 None
 1.04A 5dzkc-4rlvA:
undetectable
5dzkq-4rlvA:
undetectable		 5dzkc-4rlvA:
13.96
5dzkq-4rlvA:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 5 SER A2274
ALA A2273
MET A1607
LEU A2270
 None
 1.03A 5dzkf-4rlvA:
undetectable
5dzkt-4rlvA:
undetectable		 5dzkf-4rlvA:
13.96
5dzkt-4rlvA:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 8 LEU A2182
LEU A2149
THR A2132
TYR A2135
 None
 0.99A 5hbsA-4rlvA:
undetectable		 5hbsA-4rlvA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 9 ALA A2769
GLN A2770
PRO A2787
LEU A2813
ILE A2777
 None
 1.24A 5i73A-4rlvA:
undetectable		 5i73A-4rlvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 11 ASP A2204
THR A2205
VAL A2226
MET A2225
LEU A2211
 None
 1.47A 5jkwA-4rlvA:
undetectable		 5jkwA-4rlvA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		5 / 5 PRO A2194
ALA A2195
ALA A2168
ILE A2198
LEU A1614
 None
 1.12A 5jncD-4rlvA:
undetectable		 5jncD-4rlvA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 CYH A2406
LYS A2407
HIS A2443
 None
SO4  A2908 (-2.5A)
None
 1.11A 5js5A-4rlvA:
undetectable		 5js5A-4rlvA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 7 LEU A2319
LEU A2303
ALA A2306
ALA A2307
 None
 0.88A 6a7jA-4rlvA:
undetectable		 6a7jA-4rlvA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 6 GLY A2629
THR A2659
GLN A2661
TYR A2630
 None
 1.28A 6ag0A-4rlvA:
undetectable		 6ag0A-4rlvA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG A2506
LYS A1584
ARG A2539
 None
 1.20A 6az3C-4rlvA:
undetectable
6az3L-4rlvA:
undetectable
6az3M-4rlvA:
undetectable		 6az3C-4rlvA:
7.03
6az3L-4rlvA:
6.66
6az3M-4rlvA:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 6 LEU A2483
ALA A2488
THR A2433
ASN A2461
 None
 0.86A 6f88A-4rlvA:
undetectable		 6f88A-4rlvA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4rlv ANKYRIN-1, ANKYRIN-2
(Homo
sapiens;
Mus
musculus) 		4 / 6 LEU A2483
ALA A2488
THR A2433
ASN A2461
 None
 0.89A 6f88B-4rlvA:
undetectable		 6f88B-4rlvA:
6.21