SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 4 ARG A 304
ALA A 303
ALA A  69
GLU A   9
 None
 1.18A 1e7bA-4rm7A:
undetectable		 1e7bA-4rm7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 11 LEU A  91
LEU A  94
GLU A  98
ARG A 110
LEU A  67
 None
 1.01A 1g50A-4rm7A:
3.0		 1g50A-4rm7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		3 / 3 ASP A 176
THR A 174
GLU A 221
 None
 0.83A 1pj7A-4rm7A:
undetectable		 1pj7A-4rm7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 7 ALA A   0
ARG A 296
TYR A   2
PHE A  68
 None
 1.19A 2ajvH-4rm7A:
undetectable
2ajvL-4rm7A:
undetectable		 2ajvH-4rm7A:
18.43
2ajvL-4rm7A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 7 ALA A   0
TYR A 300
ARG A 296
TYR A   2
 None
 1.01A 2ajvH-4rm7A:
undetectable
2ajvL-4rm7A:
undetectable		 2ajvH-4rm7A:
18.43
2ajvL-4rm7A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.16A 2eimJ-4rm7A:
undetectable		 2eimJ-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.20A 2eimW-4rm7A:
undetectable		 2eimW-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 10 LEU A 225
ALA A  99
LEU A 238
ILE A 125
PHE A 184
 None
 1.08A 2w9hA-4rm7A:
undetectable		 2w9hA-4rm7A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 9 TRP A 264
VAL A 281
ILE A 337
ARG A 268
GLY A 267
 None
 1.43A 2xfsB-4rm7A:
0.0		 2xfsB-4rm7A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.26A 3ag1J-4rm7A:
undetectable		 3ag1J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.19A 3ag2J-4rm7A:
undetectable		 3ag2J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.18A 3ag4J-4rm7A:
undetectable		 3ag4J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		3 / 3 PHE A 100
SER A 228
GLN A 234
 None
 0.94A 3smtA-4rm7A:
undetectable		 3smtA-4rm7A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 6 ARG A 266
ILE A 337
VAL A 281
LEU A 285
 None
 1.10A 4em2A-4rm7A:
1.0		 4em2A-4rm7A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 12 ILE A  74
PHE A  46
LEU A  91
GLY A  55
PHE A  51
 None
 1.08A 4ls7A-4rm7A:
undetectable
4ls7B-4rm7A:
undetectable		 4ls7A-4rm7A:
22.60
4ls7B-4rm7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_ACTA502_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 4 LYS A  44
ARG A 118
GLY A 117
ASP A 115
 None
 1.35A 4ryaA-4rm7A:
undetectable		 4ryaA-4rm7A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 12 LEU A  67
TYR A 306
VAL A  71
ILE A  74
LEU A  92
 None
 1.19A 4yvpB-4rm7A:
undetectable		 4yvpB-4rm7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 12 THR A 293
GLU A  75
GLY A 252
ILE A 352
ALA A 250
 None
 1.21A 5kvaA-4rm7A:
undetectable		 5kvaA-4rm7A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 12 THR A 293
GLU A  75
GLY A 252
ILE A 352
ALA A 250
 None
 1.21A 5kvaB-4rm7A:
undetectable		 5kvaB-4rm7A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.29A 5w97J-4rm7A:
undetectable		 5w97J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.22A 5wauJ-4rm7A:
undetectable		 5wauJ-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.25A 5x19J-4rm7A:
undetectable		 5x19J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.25A 5x1bJ-4rm7A:
undetectable		 5x1bJ-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.28A 5x1bW-4rm7A:
undetectable		 5x1bW-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.25A 5x1fW-4rm7A:
undetectable		 5x1fW-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 10 VAL A 330
GLU A 329
ALA A 254
LEU A 292
ASN A 294
 None
 1.06A 5x6yB-4rm7A:
undetectable		 5x6yB-4rm7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.20A 5z86J-4rm7A:
undetectable		 5z86J-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		5 / 12 LEU A  13
LEU A   5
ALA A   0
LEU A  72
LEU A 251
 None
 0.96A 6b0cD-4rm7A:
undetectable		 6b0cD-4rm7A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.24A 6nknJ-4rm7A:
undetectable		 6nknJ-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rm7 ACYL-COA
DEHYDROGENASE
(Slackia
heliotrinireduce
ns) 		4 / 5 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.23A 6nknW-4rm7A:
undetectable		 6nknW-4rm7A:
12.38