SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_B_SAMB301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	5 / 12	GLU A 144 GLY A 143 ASP A 145 ALA A 146 ALA A 150	None	1.27A	2br4B-4rmpA: undetectable	2br4B-4rmpA: 24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_D_SAMD301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	3 / 3	LYS A 6 ASP A 154 ASP A 100	None	0.98A	2br4D-4rmpA: undetectable	2br4D-4rmpA: 24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FBX_A_ACTA608_0 (PUTATIVE PHOSPHOLIPASE B-LIKE 2)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	3 / 3	GLU A 128 VAL A 130 CYH A 132	None	0.88A	3fbxA-4rmpA: undetectable	3fbxA-4rmpA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_B_EAAB213_1 (GLUTATHIONE S-TRANSFERASE P)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	4 / 7	TYR A 116 VAL A 112 VAL A 156 GLY A 108	None None None CYC A 201 ( 3.8A)	1.13A	3kmoB-4rmpA: undetectable	3kmoB-4rmpA: 26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_B_010B607_0 (HNL ISOENZYME 5)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	5 / 10	ALA A 129 ALA A 125 VAL A 65 LEU A 82 VAL A 66	CYC A 201 ( 3.7A) CYC A 201 (-3.4A) CYC A 201 (-4.1A) None None	1.44A	5eb5B-4rmpA: undetectable	5eb5B-4rmpA: 14.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BR4_B_SAMB301_0","CEPHALOSPORIN HYDROXYLASE CMCI","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",5,"GLU A 144;GLY A 143;ASP A 145;ALA A 146;ALA A 150","None","1.27A","2br4B-4rmpA:undetectable","2br4B-4rmpA:24.48"],["2BR4_D_SAMD301_1","CEPHALOSPORIN HYDROXYLASE CMCI","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",3,"LYS A   6;ASP A 154;ASP A 100","None","0.98A","2br4D-4rmpA:undetectable","2br4D-4rmpA:24.48"],["3FBX_A_ACTA608_0","PUTATIVE PHOSPHOLIPASE B-LIKE 2","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",3,"GLU A 128;VAL A 130;CYH A 132","None","0.88A","3fbxA-4rmpA:undetectable","3fbxA-4rmpA:14.55"],["3KMO_B_EAAB213_1","GLUTATHIONE S-TRANSFERASE P","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",4,"TYR A 116;VAL A 112;VAL A 156;GLY A 108","None;None;None;CYC A 201 ( 3.8A)","1.13A","3kmoB-4rmpA:undetectable","3kmoB-4rmpA:26.51"],["5EB5_B_010B607_0","HNL ISOENZYME 5","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",5,"ALA A 129;ALA A 125;VAL A  65;LEU A  82;VAL A  66","CYC A 201 ( 3.7A);CYC A 201 (-3.4A);CYC A 201 (-4.1A);None;None","1.44A","5eb5B-4rmpA:undetectable","5eb5B-4rmpA:14.31"]]