SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 169
ILE A 203
ALA A 207
SER A 209
LEU A 210
 None
 1.14A 1eqgA-4rniA:
undetectable		 1eqgA-4rniA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 169
ILE A 203
ALA A 207
SER A 209
LEU A 210
 None
 1.17A 1eqgB-4rniA:
undetectable		 1eqgB-4rniA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  75
GLY A  71
VAL A  67
LEU A 109
LEU A 131
 None
 0.99A 1nhzA-4rniA:
undetectable		 1nhzA-4rniA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 169
ILE A 203
ALA A 207
SER A 209
LEU A 210
 None
 1.09A 2aylB-4rniA:
undetectable		 2aylB-4rniA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  30
ASP A  31
ARG A  34
MET A 245
 None
 1.43A 3qx3A-4rniA:
undetectable		 3qx3A-4rniA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  30
ASP A  31
ARG A  34
MET A 245
 None
 1.39A 3qx3B-4rniA:
undetectable		 3qx3B-4rniA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  78
LEU A 117
LEU A  75
ASN A  98
ILE A 113
 None
 1.21A 3wdmC-4rniA:
undetectable		 3wdmC-4rniA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 147
LEU A 150
ILE A 157
ASN A  98
LEU A 136
 None
 0.90A 4lmnA-4rniA:
undetectable		 4lmnA-4rniA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 227
LEU A 228
ALA A 200
GLN A 222
 None
 1.10A 6b89B-4rniA:
undetectable		 6b89B-4rniA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4rni MOTILITY REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  83
LEU A  82
ALA A  38
GLN A  27
 None
 1.06A 6b89A-4rniA:
1.5		 6b89A-4rniA:
12.74