SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rnw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H60_A_STRA500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 9 THR A 136
TYR A 181
HIS A 290
TYR A 295
TYR A  75
 FMN  A 401 (-3.7A)
EPE  A 402 ( 3.8A)
FMN  A 401 ( 3.5A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.78A 1h60A-4rnwA:
7.4		 1h60A-4rnwA:
28.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ABA_A_STRA1500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 9 THR A 136
TYR A 181
HIS A 290
TYR A 295
TYR A  75
 FMN  A 401 (-3.7A)
EPE  A 402 ( 3.8A)
FMN  A 401 ( 3.5A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.75A 2abaA-4rnwA:
31.8		 2abaA-4rnwA:
28.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 LEU A 126
ILE A 121
VAL A  57
PHE A 383
HIS A 385
 None
 1.35A 2qo4A-4rnwA:
undetectable		 2qo4A-4rnwA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 ASP A 224
LEU A 226
PHE A 173
ASN A 183
ASP A 182
 None
None
None
EDO  A 406 (-3.9A)
EDO  A 406 (-4.1A)
 1.43A 2x2iA-4rnwA:
7.1		 2x2iA-4rnwA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 7 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.83A 3bjwB-4rnwA:
undetectable		 3bjwB-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 7 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.84A 3bjwF-4rnwA:
undetectable		 3bjwF-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 7 VAL A 273
LYS A 277
ILE A 280
GLY A 283
 None
 0.89A 3bjwH-4rnwA:
undetectable		 3bjwH-4rnwA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.39A 3nt1A-4rnwA:
undetectable		 3nt1A-4rnwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.41A 3nt1B-4rnwA:
undetectable		 3nt1B-4rnwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 ASN A 350
PHE A 349
PHE A 222
MET A 242
ALA A 220
 None
EDO  A 403 ( 3.9A)
EDO  A 409 ( 4.7A)
None
None
 1.44A 3nuvA-4rnwA:
undetectable		 3nuvA-4rnwA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 11 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.33A 3pghB-4rnwA:
undetectable		 3pghB-4rnwA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.33A 3pghC-4rnwA:
undetectable		 3pghC-4rnwA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.33A 3pghD-4rnwA:
undetectable		 3pghD-4rnwA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 VAL A 384
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.06A 3rr3A-4rnwA:
undetectable		 3rr3A-4rnwA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.28A 3rr3C-4rnwA:
undetectable		 3rr3C-4rnwA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.28A 3rr3D-4rnwA:
undetectable		 3rr3D-4rnwA:
22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPW_A_NCAA412_0
(OLD YELLOW ENZYME
2.6 (OYE2.6), NADPH
DEHYDROGENASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 9 THR A 136
HIS A 290
TYR A 295
PHE A 349
TYR A  75
 FMN  A 401 (-3.7A)
FMN  A 401 ( 3.5A)
EPE  A 402 (-4.4A)
EDO  A 403 ( 3.9A)
EPE  A 402 ( 3.7A)
 0.37A 3upwA-4rnwA:
37.2		 3upwA-4rnwA:
34.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 6 TYR A  75
ARG A 139
ASP A  70
TYR A  82
 EPE  A 402 ( 3.7A)
None
None
None
 1.23A 3wfaA-4rnwA:
2.2
3wfaB-4rnwA:
7.4		 3wfaA-4rnwA:
20.25
3wfaB-4rnwA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 7 THR A 136
TRP A 215
HIS A 290
ASN A 293
TYR A 295
TYR A  75
 FMN  A 401 (-3.7A)
None
FMN  A 401 ( 3.5A)
EDO  A 403 ( 3.7A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.27A 4a3uA-4rnwA:
31.4		 4a3uA-4rnwA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 7 THR A 136
TRP A 215
HIS A 290
ASN A 293
TYR A 295
TYR A  75
 FMN  A 401 (-3.7A)
None
FMN  A 401 ( 3.5A)
EDO  A 403 ( 3.7A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.26A 4a3uB-4rnwA:
31.4		 4a3uB-4rnwA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 7 THR A 136
TRP A 215
HIS A 290
ASN A 293
TYR A 295
 FMN  A 401 (-3.7A)
None
FMN  A 401 ( 3.5A)
EDO  A 403 ( 3.7A)
EPE  A 402 (-4.4A)
 0.22A 4awuA-4rnwA:
8.0		 4awuA-4rnwA:
27.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 6 THR A 136
HIS A 290
TYR A 295
TYR A  75
 FMN  A 401 (-3.7A)
FMN  A 401 ( 3.5A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.19A 4df2A-4rnwA:
37.1		 4df2A-4rnwA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 6 TYR A 181
HIS A 290
TYR A 295
TYR A  75
 EPE  A 402 ( 3.8A)
FMN  A 401 ( 3.5A)
EPE  A 402 (-4.4A)
EPE  A 402 ( 3.7A)
 0.86A 4df2A-4rnwA:
37.1		 4df2A-4rnwA:
34.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 GLN A 192
ILE A 199
TYR A 156
PRO A 134
ILE A 167
 None
None
None
FMN  A 401 (-3.7A)
None
 1.30A 4drhD-4rnwA:
undetectable		 4drhD-4rnwA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 VAL A 384
LEU A 341
VAL A 367
GLY A 369
ALA A 368
 None
 1.10A 4otyA-4rnwA:
undetectable		 4otyA-4rnwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 ALA A 284
SER A 279
GLY A 335
GLY A 340
LEU A 214
 None
 1.27A 4uilH-4rnwA:
undetectable
4uilL-4rnwA:
undetectable		 4uilH-4rnwA:
19.85
4uilL-4rnwA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 11 ALA A 172
VAL A 210
ASP A 285
SER A 279
GLY A 283
 None
 0.79A 4xp4A-4rnwA:
0.3		 4xp4A-4rnwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 ALA A 220
GLY A 218
GLY A 179
ALA A 236
LEU A 297
 None
 0.95A 5c0oG-4rnwA:
undetectable		 5c0oG-4rnwA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 LEU A 214
GLN A 213
GLY A 340
ASN A 293
VAL A 216
 None
FMN  A 401 (-3.0A)
None
EDO  A 403 ( 3.7A)
None
 1.36A 5d0yA-4rnwA:
undetectable		 5d0yA-4rnwA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		6 / 12 VAL A 384
LEU A 341
LEU A 386
VAL A 367
GLY A 369
ALA A 368
 None
 1.37A 5jvzA-4rnwA:
undetectable		 5jvzA-4rnwA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		3 / 3 GLU A 154
TYR A 155
ARG A 159
 None
 0.83A 5uunA-4rnwA:
undetectable		 5uunA-4rnwA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		3 / 3 GLU A 154
TYR A 155
ARG A 159
 None
 0.84A 5uunB-4rnwA:
undetectable		 5uunB-4rnwA:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		7 / 8 THR A 136
TRP A 215
HIS A 290
ASN A 293
TYR A 295
PHE A 349
TYR A  75
 FMN  A 401 (-3.7A)
None
FMN  A 401 ( 3.5A)
EDO  A 403 ( 3.7A)
EPE  A 402 (-4.4A)
EDO  A 403 ( 3.9A)
EPE  A 402 ( 3.7A)
 0.38A 5v4vA-4rnwA:
9.4		 5v4vA-4rnwA:
60.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		7 / 8 THR A 136
TRP A 215
HIS A 290
ASN A 293
TYR A 295
PHE A 349
TYR A  75
 FMN  A 401 (-3.7A)
None
FMN  A 401 ( 3.5A)
EDO  A 403 ( 3.7A)
EPE  A 402 (-4.4A)
EDO  A 403 ( 3.9A)
EPE  A 402 ( 3.7A)
 0.37A 5v4vB-4rnwA:
7.9		 5v4vB-4rnwA:
60.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 8 GLY A  63
ARG A 162
GLN A 161
ASP A  58
 None
 1.08A 5vlmA-4rnwA:
undetectable		 5vlmA-4rnwA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 8 LEU A 343
ILE A  15
ALA A 320
LEU A 324
 None
 0.78A 5y7pC-4rnwA:
undetectable		 5y7pC-4rnwA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 4 GLY A 180
ARG A 228
ASN A 225
LEU A 226
 None
None
EDO  A 406 (-3.7A)
None
 1.27A 6b58A-4rnwA:
undetectable		 6b58A-4rnwA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 ASP A  10
ASN A   9
PHE A  11
PRO A 389
GLY A  24
 None
None
None
None
FMN  A 401 (-3.3A)
 1.30A 6gnfA-4rnwA:
undetectable		 6gnfA-4rnwA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 VAL A  32
ASN A   9
PHE A  11
PRO A 389
GLY A  24
 None
None
None
None
FMN  A 401 (-3.3A)
 1.35A 6gnfA-4rnwA:
undetectable		 6gnfA-4rnwA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		5 / 12 VAL A  32
ASP A  10
ASN A   9
PRO A 389
GLY A  24
 None
None
None
None
FMN  A 401 (-3.3A)
 1.12A 6gnfC-4rnwA:
undetectable		 6gnfC-4rnwA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4rnw NADPH DEHYDROGENASE
1
(Saccharomyces
pastorianus) 		4 / 6 PRO A  54
ILE A  83
TYR A 155
GLU A 154
 None
 1.04A 6gqiA-4rnwA:
undetectable		 6gqiA-4rnwA:
22.80