SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.92A 1v54A-4rq9A:
undetectable
1v54J-4rq9A:
undetectable		 1v54A-4rq9A:
18.92
1v54J-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 7 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.96A 1v54N-4rq9A:
undetectable
1v54W-4rq9A:
undetectable		 1v54N-4rq9A:
18.92
1v54W-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.94A 2dyrA-4rq9A:
undetectable
2dyrJ-4rq9A:
undetectable		 2dyrA-4rq9A:
18.92
2dyrJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 7 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.96A 2dyrN-4rq9A:
undetectable
2dyrW-4rq9A:
undetectable		 2dyrN-4rq9A:
18.92
2dyrW-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.92A 2dysA-4rq9A:
undetectable
2dysJ-4rq9A:
undetectable		 2dysA-4rq9A:
18.92
2dysJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.98A 2dysN-4rq9A:
undetectable
2dysW-4rq9A:
undetectable		 2dysN-4rq9A:
18.92
2dysW-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.91A 2eijA-4rq9A:
undetectable
2eijJ-4rq9A:
undetectable		 2eijA-4rq9A:
18.92
2eijJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.88A 2eilA-4rq9A:
undetectable
2eilJ-4rq9A:
undetectable		 2eilA-4rq9A:
18.92
2eilJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 8 ASP A 208
TYR A 177
GLY A 185
PRO A 205
 BLA  A 401 (-3.6A)
BLA  A 401 ( 4.5A)
None
None
 0.83A 2ys6A-4rq9A:
undetectable		 2ys6A-4rq9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 1.03A 2zxwA-4rq9A:
undetectable
2zxwJ-4rq9A:
undetectable		 2zxwA-4rq9A:
18.92
2zxwJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 1.00A 3abmA-4rq9A:
undetectable
3abmJ-4rq9A:
undetectable		 3abmA-4rq9A:
18.92
3abmJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 8 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.91A 3ag3N-4rq9A:
undetectable
3ag3W-4rq9A:
undetectable		 3ag3N-4rq9A:
18.92
3ag3W-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.94A 3asnA-4rq9A:
undetectable
3asnJ-4rq9A:
undetectable		 3asnA-4rq9A:
18.92
3asnJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		4 / 6 LEU A 123
ARG A 118
THR A  46
LEU A  45
 None
 0.94A 3asoA-4rq9A:
undetectable
3asoJ-4rq9A:
undetectable		 3asoA-4rq9A:
18.92
3asoJ-4rq9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		5 / 10 VAL A 165
ALA A 191
SER A 273
LEU A 276
VAL A 161
 None
SRT  A 402 (-3.7A)
BLA  A 401 (-2.5A)
None
None
 1.16A 4eilB-4rq9A:
undetectable		 4eilB-4rq9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		5 / 10 LEU A  89
LEU A  95
ALA A 112
LEU A  68
LEU A 119
 None
 1.21A 4p65A-4rq9A:
undetectable
4p65B-4rq9A:
undetectable
4p65F-4rq9A:
undetectable
4p65H-4rq9A:
undetectable		 4p65A-4rq9A:
5.49
4p65B-4rq9A:
6.69
4p65F-4rq9A:
6.69
4p65H-4rq9A:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		5 / 12 ASP A 105
LEU A  84
SER A 126
LEU A 121
LEU A  56
 None
None
GOL  A 415 ( 4.3A)
None
None
 1.18A 6ew0F-4rq9A:
undetectable		 6ew0F-4rq9A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 4rq9 PHOTORECEPTOR-HISTID
INE KINASE BPHP
(Stigmatella
aurantiaca) 		5 / 12 ASP A 105
LEU A  84
SER A 126
LEU A 121
LEU A  56
 None
None
GOL  A 415 ( 4.3A)
None
None
 1.19A 6ew0G-4rq9A:
undetectable		 6ew0G-4rq9A:
14.47