SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rrp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.77A 1v54N-4rrpM:
undetectable
1v54W-4rrpM:
undetectable		 1v54N-4rrpM:
13.87
1v54W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		5 / 12 GLY M   8
VAL M 109
LEU M   6
LEU M  12
LEU M  97
 None
 1.06A 1ya4C-4rrpM:
undetectable		 1ya4C-4rrpM:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.71A 2dyrN-4rrpM:
undetectable
2dyrW-4rrpM:
undetectable		 2dyrN-4rrpM:
13.87
2dyrW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.77A 2eijN-4rrpM:
undetectable
2eijW-4rrpM:
undetectable		 2eijN-4rrpM:
13.87
2eijW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.74A 2eikN-4rrpM:
undetectable
2eikW-4rrpM:
undetectable		 2eikN-4rrpM:
13.87
2eikW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.74A 2eilN-4rrpM:
undetectable
2eilW-4rrpM:
undetectable		 2eilN-4rrpM:
13.87
2eilW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 6 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.81A 2einN-4rrpM:
undetectable
2einW-4rrpM:
undetectable		 2einN-4rrpM:
13.87
2einW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.76A 3ablA-4rrpM:
undetectable
3ablJ-4rrpM:
undetectable		 3ablA-4rrpM:
13.87
3ablJ-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.77A 3ablN-4rrpM:
undetectable
3ablW-4rrpM:
undetectable		 3ablN-4rrpM:
13.87
3ablW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 6 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.78A 3ag1N-4rrpM:
undetectable
3ag1W-4rrpM:
undetectable		 3ag1N-4rrpM:
13.87
3ag1W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.69A 3ag3N-4rrpM:
undetectable
3ag3W-4rrpM:
undetectable		 3ag3N-4rrpM:
13.87
3ag3W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 8 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.78A 3asnN-4rrpM:
undetectable
3asnW-4rrpM:
undetectable		 3asnN-4rrpM:
13.87
3asnW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 6 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.84A 3wg7N-4rrpM:
undetectable
3wg7W-4rrpM:
undetectable		 3wg7N-4rrpM:
13.87
3wg7W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.91A 5b1bN-4rrpM:
undetectable
5b1bW-4rrpM:
undetectable		 5b1bN-4rrpM:
13.87
5b1bW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.91A 5b3sN-4rrpM:
undetectable
5b3sW-4rrpM:
undetectable		 5b3sN-4rrpM:
13.87
5b3sW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		3 / 3 ASN M  13
ALA M  16
ARG M 137
 None
 0.78A 5cvtB-4rrpM:
undetectable		 5cvtB-4rrpM:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		5 / 12 VAL M 130
ALA M  81
PRO M  79
ILE M 139
ILE M 135
 None
 1.13A 5hbsA-4rrpM:
undetectable		 5hbsA-4rrpM:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.75A 5iy5A-4rrpM:
undetectable
5iy5J-4rrpM:
undetectable		 5iy5A-4rrpM:
13.87
5iy5J-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.82A 5iy5N-4rrpM:
undetectable
5iy5W-4rrpM:
undetectable		 5iy5N-4rrpM:
13.87
5iy5W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 6 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.93A 5z86N-4rrpM:
undetectable
5z86W-4rrpM:
undetectable		 5z86N-4rrpM:
13.87
5z86W-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 6 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.87A 5zcoN-4rrpM:
undetectable
5zcoW-4rrpM:
undetectable		 5zcoN-4rrpM:
13.87
5zcoW-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		5 / 12 ILE M   9
VAL M 132
LEU M  89
GLY M 110
LEU M  42
 None
 1.26A 6a7pA-4rrpM:
undetectable		 6a7pA-4rrpM:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.87A 6nmfA-4rrpM:
undetectable
6nmfJ-4rrpM:
undetectable		 6nmfA-4rrpM:
13.87
6nmfJ-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 7 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.93A 6nmpA-4rrpM:
undetectable
6nmpJ-4rrpM:
undetectable		 6nmpA-4rrpM:
13.87
6nmpJ-4rrpM:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rrp ANTIGEN ASF1P
(Saccharomyces
cerevisiae) 		4 / 5 ILE M   9
ARG M 108
THR M  43
LEU M  42
 None
 0.92A 6nmpN-4rrpM:
undetectable
6nmpW-4rrpM:
undetectable		 6nmpN-4rrpM:
13.87
6nmpW-4rrpM:
18.94