SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4rsj CHROMOSOME PARTITION
PROTEIN SMC
(Pyrococcus
furiosus) 		4 / 4 ILE A 530
LEU A 526
VAL A 553
ALA A 560
 None
 0.99A 1mz9A-4rsjA:
2.7		 1mz9A-4rsjA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4rsj CHROMOSOME PARTITION
PROTEIN SMC
(Pyrococcus
furiosus) 		5 / 12 ALA A 563
GLY A 521
ILE A 606
GLY A 524
LEU A 529
 None
 1.18A 4n48B-4rsjA:
undetectable		 4n48B-4rsjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4rsj CHROMOSOME PARTITION
PROTEIN SMC
(Pyrococcus
furiosus) 		5 / 12 ALA A 563
GLY A 521
PHE A 577
ILE A 606
GLY A 524
 None
 1.23A 4n48B-4rsjA:
undetectable		 4n48B-4rsjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4rsj CHROMOSOME PARTITION
PROTEIN SMC
(Pyrococcus
furiosus) 		4 / 4 ARG A 627
ILE A 630
TYR A 643
ILE A 649
 None
 1.32A 5odhG-4rsjA:
undetectable		 5odhG-4rsjA:
17.59