SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.19A 1p6kA-4rsoA:
undetectable		 1p6kA-4rsoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.18A 1p6kB-4rsoA:
undetectable		 1p6kB-4rsoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.17A 1rs6A-4rsoA:
undetectable		 1rs6A-4rsoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.19A 1rs6B-4rsoA:
undetectable		 1rs6B-4rsoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.16A 1rs7B-4rsoA:
undetectable		 1rs7B-4rsoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.18A 1zzqA-4rsoA:
undetectable		 1zzqA-4rsoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.18A 1zzqB-4rsoA:
undetectable		 1zzqB-4rsoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.17A 1zzuA-4rsoA:
undetectable		 1zzuA-4rsoA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.18A 1zzuB-4rsoA:
undetectable		 1zzuB-4rsoA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 PHE A 286
PHE A 315
PHE A 413
 None
 0.82A 2od9A-4rsoA:
undetectable		 2od9A-4rsoA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 PHE A 286
PHE A 315
PHE A 413
 None
 0.82A 2qqgA-4rsoA:
undetectable		 2qqgA-4rsoA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 TRP A 281
GLN A 646
TRP A 247
 None
 1.34A 2vqyA-4rsoA:
undetectable		 2vqyA-4rsoA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.21A 3n62B-4rsoA:
undetectable		 3n62B-4rsoA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 TYR A 426
HIS A 428
ARG A 734
 None
 1.04A 4e7bC-4rsoA:
undetectable		 4e7bC-4rsoA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 TYR A 555
THR A 491
VAL A 540
ILE A 542
 None
 0.78A 4l4cB-4rsoA:
undetectable		 4l4cB-4rsoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.44A 4v2yA-4rsoA:
undetectable		 4v2yA-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.43A 4v2yB-4rsoA:
undetectable		 4v2yB-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.46A 4v2zA-4rsoA:
undetectable		 4v2zA-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.40A 4v2zB-4rsoA:
undetectable		 4v2zB-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.45A 4v30A-4rsoA:
undetectable		 4v30A-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.33A 4v30B-4rsoA:
undetectable		 4v30B-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 6 LEU A 352
TYR A 354
PRO A 353
TYR A 377
 None
 1.29A 4z4gA-4rsoA:
undetectable		 4z4gA-4rsoA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.44A 5amiA-4rsoA:
undetectable		 5amiA-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 8 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.45A 5amiB-4rsoA:
undetectable		 5amiB-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.44A 5amjA-4rsoA:
undetectable		 5amjA-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.41A 5amjB-4rsoA:
undetectable		 5amjB-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.40A 5amkB-4rsoA:
undetectable		 5amkB-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.46A 5oh1A-4rsoA:
undetectable		 5oh1A-4rsoA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.39A 5oh1B-4rsoA:
undetectable		 5oh1B-4rsoA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.44A 5oh3A-4rsoA:
undetectable		 5oh3A-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		4 / 7 PRO A 310
PHE A 638
TRP A 619
TYR A 354
 None
 1.41A 5oh3B-4rsoA:
undetectable		 5oh3B-4rsoA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 CYH A 483
MET A 524
ASN A 570
 None
 1.18A 5qh8A-4rsoA:
undetectable		 5qh8A-4rsoA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		3 / 3 GLN A 299
TYR A 701
ASN A 303
 None
 0.95A 6dwdC-4rsoA:
undetectable		 6dwdC-4rsoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4rso CAPSID PROTEIN VP1
(Non-human
primate
Adeno-associated
virus) 		5 / 12 GLY A 616
GLY A 637
ALA A 620
PHE A 417
PHE A 308
 None
 1.00A 6nj9K-4rsoA:
undetectable		 6nj9K-4rsoA:
18.46