SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rsw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 12 PRO A 310
ALA A 247
LEU A 251
ALA A 249
ILE A 277
 None
 1.25A 2jjpA-4rswA:
undetectable		 2jjpA-4rswA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 12 ILE A 234
LEU A 278
GLY A 299
LEU A 251
GLY A 304
 None
 1.09A 3vasB-4rswA:
undetectable		 3vasB-4rswA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4rsw HOPA1
(Pseudomonas
syringae) 		3 / 3 THR A 259
ASN A 281
SER A 257
 None
 0.68A 4tvtA-4rswA:
undetectable		 4tvtA-4rswA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4rsw HOPA1
(Pseudomonas
syringae) 		3 / 3 TYR A 279
ARG A 216
LYS A 262
 None
 1.17A 4wq5B-4rswA:
undetectable		 4wq5B-4rswA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4rsw HOPA1
(Pseudomonas
syringae) 		4 / 7 THR A 273
ASP A 274
TYR A 149
GLY A 334
 None
 0.92A 5hwaA-4rswA:
undetectable		 5hwaA-4rswA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 4rsw HOPA1
(Pseudomonas
syringae) 		3 / 3 LYS A 220
GLN A 175
ASN A 179
 None
 0.86A 5l2tA-4rswA:
undetectable		 5l2tA-4rswA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4rsw HOPA1
(Pseudomonas
syringae) 		3 / 3 THR A 250
MET A 252
HIS A 255
 None
 1.02A 5uunA-4rswA:
undetectable		 5uunA-4rswA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 10 PRO A 187
LEU A 174
LYS A 220
ILE A 204
GLY A 201
 None
 1.46A 6dlzA-4rswA:
undetectable
6dlzD-4rswA:
undetectable		 6dlzA-4rswA:
13.73
6dlzD-4rswA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 10 ILE A 204
GLY A 201
PRO A 187
LEU A 174
LYS A 220
 None
 1.46A 6dlzB-4rswA:
undetectable
6dlzC-4rswA:
undetectable		 6dlzB-4rswA:
13.73
6dlzC-4rswA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 10 PRO A 187
LEU A 174
LYS A 220
ILE A 204
GLY A 201
 None
 1.46A 6dm1A-4rswA:
undetectable
6dm1D-4rswA:
undetectable		 6dm1A-4rswA:
13.73
6dm1D-4rswA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4rsw HOPA1
(Pseudomonas
syringae) 		5 / 10 ILE A 204
GLY A 201
PRO A 187
LEU A 174
LYS A 220
 None
 1.46A 6dm1B-4rswA:
undetectable
6dm1C-4rswA:
undetectable		 6dm1B-4rswA:
13.73
6dm1C-4rswA:
13.73