SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rsx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 ARG A 359
ALA A 137
LYS A 138
GLU A 141
 None
 1.12A 1e7cA-4rsxA:
2.1		 1e7cA-4rsxA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ASP A 278
GLY A 265
ILE A 221
ILE A 238
 None
 0.81A 1n49D-4rsxA:
undetectable		 1n49D-4rsxA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 4 LEU A 177
THR A 176
ILE A 268
HIS A 273
 None
 1.25A 2jfaB-4rsxA:
undetectable		 2jfaB-4rsxA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLN A 233
GLY A 368
SER A 340
LEU A 364
SER A 316
 None
 1.26A 3d91B-4rsxA:
undetectable		 3d91B-4rsxA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 151
TYR A 152
ILE A 154
GLN A 157
 None
 0.98A 3hgxA-4rsxA:
undetectable		 3hgxA-4rsxA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ALA A 140
LEU A 349
SER A 363
LEU A 360
ALA A 348
 None
 1.21A 4zbrA-4rsxA:
2.0		 4zbrA-4rsxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4rsx TYPE III EFFECTOR
HOPA1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A 174
LEU A 248
LEU A 177
ILE A 256
TYR A 219
 None
 1.23A 5ienB-4rsxA:
undetectable		 5ienB-4rsxA:
23.35