SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 HIS A  18
THR A  90
HIS A  86
HIS A  69
TYR A  94
 NI  A 201 ( 3.4A)
None
TRS  A 202 (-3.4A)
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
 1.18A 1j36A-4rt5A:
undetectable		 1j36A-4rt5A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 HIS A  18
THR A  90
HIS A  86
HIS A  69
TYR A  94
 NI  A 201 ( 3.4A)
None
TRS  A 202 (-3.4A)
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
 1.18A 1j36B-4rt5A:
undetectable		 1j36B-4rt5A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.51A 4ir0A-4rt5A:
6.7
4ir0B-4rt5A:
6.5		 4ir0A-4rt5A:
23.72
4ir0B-4rt5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.53A 4ir0A-4rt5A:
6.7
4ir0B-4rt5A:
6.5		 4ir0A-4rt5A:
23.72
4ir0B-4rt5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.49A 4jd1A-4rt5A:
6.6
4jd1B-4rt5A:
6.5		 4jd1A-4rt5A:
23.72
4jd1B-4rt5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.54A 4jd1A-4rt5A:
6.6
4jd1B-4rt5A:
6.5		 4jd1A-4rt5A:
23.72
4jd1B-4rt5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.49A 4jh3A-4rt5A:
6.3
4jh3B-4rt5A:
6.3		 4jh3A-4rt5A:
23.18
4jh3B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.50A 4jh3A-4rt5A:
6.3
4jh3B-4rt5A:
6.3		 4jh3A-4rt5A:
23.18
4jh3B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.54A 4jh4A-4rt5A:
6.4
4jh4B-4rt5A:
6.3		 4jh4A-4rt5A:
23.18
4jh4B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.51A 4jh4A-4rt5A:
6.4
4jh4B-4rt5A:
6.3		 4jh4A-4rt5A:
23.18
4jh4B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.52A 4jh5A-4rt5A:
6.4
4jh5B-4rt5A:
6.3		 4jh5A-4rt5A:
23.18
4jh5B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 11 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.48A 4jh5A-4rt5A:
6.4
4jh5B-4rt5A:
6.3		 4jh5A-4rt5A:
23.18
4jh5B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 10 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.51A 4jh6A-4rt5A:
6.3
4jh6B-4rt5A:
6.3		 4jh6A-4rt5A:
23.18
4jh6B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 10 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.49A 4jh6A-4rt5A:
6.3
4jh6B-4rt5A:
6.3		 4jh6A-4rt5A:
23.18
4jh6B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 10 HIS A  69
TYR A  94
GLU A 104
HIS A  18
ALA A  59
 NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
NI  A 201 ( 3.4A)
None
 0.52A 4jh8A-4rt5A:
6.4
4jh8B-4rt5A:
6.3		 4jh8A-4rt5A:
23.18
4jh8B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 10 HIS A  18
ALA A  59
HIS A  69
TYR A  94
GLU A 104
 NI  A 201 ( 3.4A)
None
NI  A 201 ( 3.2A)
TRS  A 202 (-4.9A)
NI  A 201 ( 2.8A)
 0.50A 4jh8A-4rt5A:
6.4
4jh8B-4rt5A:
6.3		 4jh8A-4rt5A:
23.18
4jh8B-4rt5A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4rt5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Planctopirus
limnophila) 		5 / 12 PHE A  53
LEU A  56
LEU A  60
ALA A  42
VAL A  30
 None
 1.10A 4wnwB-4rt5A:
undetectable		 4wnwB-4rt5A:
11.68