SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rth'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 4rth MEMBRANE-EXTRINSIC
PROTEIN OF
PHOTOSYSTEM II PSBP
(Zea
mays) 		5 / 12 LEU A  87
LEU A  88
GLY A  89
GLN A  91
GLN A  64
 None
 1.23A 1p93A-4rthA:
undetectable		 1p93A-4rthA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4rth MEMBRANE-EXTRINSIC
PROTEIN OF
PHOTOSYSTEM II PSBP
(Zea
mays) 		3 / 3 TYR A 127
THR A  72
GLU A  78
 None
 0.70A 4df3A-4rthA:
undetectable		 4df3A-4rthA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4rth MEMBRANE-EXTRINSIC
PROTEIN OF
PHOTOSYSTEM II PSBP
(Zea
mays) 		3 / 3 TYR A 127
THR A  72
GLU A  78
 None
 0.71A 4df3B-4rthA:
undetectable		 4df3B-4rthA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4rth MEMBRANE-EXTRINSIC
PROTEIN OF
PHOTOSYSTEM II PSBP
(Zea
mays) 		4 / 6 PHE A  80
VAL A  84
TYR A  86
ILE A  62
 None
 0.81A 5iwuA-4rthA:
2.1		 5iwuA-4rthA:
19.08